Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Calquence CLL rr Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - All Patient Investigation
Post-marketing surveillance update for Calquence (acalabrutinib) in relapsed or refractory chronic lymphocytic leukemia, including small lym…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Cirmtuzumab Consolidation for Treatment of Patients With Detectable CLL on Venetoclax [Phase 2]
This update outlines a Phase 2 trial of Cirmtuzumab as consolidation therapy for patients with detectable chronic lymphocytic leukemia who a…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: 19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers [Phase 1]
This is a Phase 1 clinical trial update for a CAR T cell therapy (19(T2)28z1xx) in various B-cell cancers. The study is sponsored by Memoria…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial update assessing lenalidomide in combination with a vaccine therapy for patients with early-stage asymptomatic chroni…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Project to Improve Communication About Serious Illness - Pilot Study [NA]
Pilot study completed; results posted from a University of Washington project focused on improving communication about serious illness.
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of JNJ-64264681 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
This update reports the completion of a Phase 1 study evaluating JNJ-64264681 in participants with non-Hodgkin lymphoma and chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of JNJ-64264681 and JNJ-67856633 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
This is a completed Phase 1 clinical trial update for Janssen investigational agents JNJ-64264681 and JNJ-67856633 in participants with Non-…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in B-cell NHL and CLL [Phase 1]
A Phase 1 study evaluated the combination of the MALT1 inhibitor JNJ-67856633 with Ibrutinib in patients with chronic lymphocytic leukemia a…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL [Phase 3]
Phase 3 trial comparing acalabrutinib with obinutuzumab and venetoclax versus obinutuzumab and venetoclax in previously untreated high-risk …
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: LP-168 and Obinutuzumab for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Variants of This [Phase 2]
Phase 2 trial evaluating LP-168 in combination with obinutuzumab for chronic lymphocytic leukemia/small lymphocytic lymphoma and related var…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies [Phase 1, Phase 2]
Clinical trial update on CLIC-1901 for relapsed/refractory CD19-positive hematologic malignancies (Phase 1/Phase 2), currently recruiting.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Acalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia [Phase 1]
This clinical trial update describes a Phase 1 study of acalabrutinib in combination with ACP-319 for Chronic Lymphocytic Leukemia. The tria…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Anti CD19 CAR-T Combined With BTKi to Treat Newly Diagnosed High-risk CLL/SLL [NA]
This clinical trial update describes a study evaluating the combination of anti-CD19 CAR-T therapy with a BTK inhibitor to treat newly diagn…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL [Phase 2]
Phase 2 study evaluating the combination of acalabrutinib, venetoclax, and obinutuzumab as initial therapy for chronic lymphocytic leukemia;…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia
A clinical trial evaluating the role of SF3B1 mutation in assessing acute lymphoblastic leukemia and chronic lymphocytic leukemia; the study…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Phase I Dose Finding Study of MB-CART2219.1 [Phase 1]
This clinical trial update reports that a Phase I dose-finding study of MB-CART2219.1 is currently recruiting at University Hospital Tuebing…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated With Pirtobrutinib After Previous Treatment With Zanubrutinib [Phase 2]
A Phase 2 clinical trial examines clonal dynamics in chronic lymphocytic leukemia patients treated with pirtobrutinib after prior zanubrutin…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies [Phase 1]
Phase 1 clinical trial update on genetically engineered CAR T cells (EGFRt/19-28z/IL-12) for relapsed or refractory CD19+ hematologic malign…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: 64Cu-LLP2A for Imaging Hematologic Malignancies [EARLY_Phase 1]
Phase 1 imaging trial evaluating 64Cu-LLP2A in hematologic malignancies is currently recruiting, targeting multiple myeloma and various lymp…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Assesment of the Immune Response to RSV Vaccine in Patients With Myeloma, Lymphoma and Hematological Leukemia
This clinical trial update assesses the immune response to an RSV vaccine in patients with hematologic cancers, including multiple myeloma, …
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Ibrutinib in Treating Minimal Residual Disease in Patients With Chronic Lymphocytic Leukemia After Front-Line Therapy [Phase 2]
Phase 2 trial evaluating ibrutinib for achieving minimal residual disease negativity in patients with chronic lymphocytic leukemia after fro…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 1]
This clinical trial update announces a Phase 1 study of CAP-100 for relapsed/refractory chronic lymphocytic leukemia and small lymphocytic l…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: A Study of Clinical Outcomes in Chronic Lymphocytic Leukemia (CLL) Patients Treated With Venetoclax in Greece
This is a clinical trial update for a study of venetoclax in Chronic Lymphocytic Leukemia conducted in Greece. The study is currently active…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Study Venetoclax Effectiveness and Real-Life Treatment Management in Participants With Chronic Lymphocytic Leukemia
This clinical trial update discusses venetoclax effectiveness and real-life treatment management in chronic lymphocytic leukemia, with the s…