Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Biomarker for Infection Risk in CLL and MM
This update describes a biomarker study to assess infection risk in patients with multiple myeloma and chronic lymphocytic leukemia. The tri…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies [Phase 1]
A Phase 1 clinical trial update for CD19-directed CAR-T cell therapy in patients with refractory or relapsed B lymphoid malignancies is curr…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL [Phase 2]
Phase 2 trial evaluating a combination of zanubrutinib, obinutuzumab, and sonrotoclax in previously untreated chronic lymphocytic leukemia a…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Zanubrutinib in Patients With Waldenström's Macroglobulinemia, Chronic Lymphocytic Leukemia, Marginal Zone Lymphoma and Follicular Lymphoma
This clinical trial update reports that recruitment is ongoing for a study evaluating zanubrutinib in patients with Waldenström's macroglobu…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19 [Phase 1]
A Phase 1 clinical trial update describing CD19-targeted CAR T-cell immunotherapy for high-risk or relapsed CD19+ acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Safety Study of CC312 in Adult Patients With Relapsed/Refractory CD19 Positive B-cell Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 safety study of CC312 in adults with relapsed/refractory CD19-positive B-cell hematologic mal…
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EMA approval · 2025-09-19EMA Authorised: Calquence (acalabrutinib;acalabrutinib maleate) — AstraZeneca AB
EMA authorised Calquence (acalabrutinib) for use in chronic lymphocytic leukemia and small lymphocytic lymphoma; the product is manufactured…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors [NA]
A recruiting clinical trial evaluating implanted loop recorders to detect and manage arrhythmias in patients receiving Bruton tyrosine kinas…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Global Trial in APG2575 for Patients With CLL/SLL [Phase 3]
Global Phase 3 trial of APG2575 in chronic lymphocytic leukemia and small lymphocytic lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies [Phase 1, Phase 2]
GT719 Injection is being studied in a Phase 1/2 trial for recurrent or refractory CD19-positive adult B-cell malignancies, with recruitment …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation [Phase 1]
Phase 1 trial evaluating Zanubrutinib in combination with Odronextamab for Richter transformation in transformed chronic lymphocytic leukemi…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Ibrutinib in Combination With GA101 (Obinutuzumab) in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Patients. [Phase 1, Phase 2]
This update reports results from a Phase 1/2 study evaluating the combination of ibrutinib with obinutuzumab (GA101) in previously untreated…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Augmented Virtual Reality for Reducing Pain, Stress, Anxiety and Improve Self Efficacy in Adult Cancer Patients Undergoing Chemotherapy in The West Bank [NA]
This completed clinical trial evaluated augmented virtual reality as a nonpharmacologic approach to reduce pain, stress, and anxiety and to …
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment
This clinical trial update describes a study assessing vaccine responses in patients who previously received CAR-T therapy for multiple myel…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
This clinical trial update reports on safety, efficacy, and pharmacokinetics of mosunetuzumab as a single agent and with atezolizumab in chr…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia [Phase 1]
Phase 1 trial of pitavastatin in combination with venetoclax for chronic lymphocytic leukemia or acute myeloid leukemia has completed.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas [Phase 1]
This entry provides an update on an ongoing Phase 1 trial of CD19-targeted CAR T-cells (CD19.20.22) for relapsed/refractory B-cell lymphomas…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I) [Phase 1]
Phase I clinical trial update for BR101801 in adults with advanced hematologic malignancies; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL [Phase 2]
A Phase 2 pilot study evaluating metformin therapy in patients with relapsed or untreated chronic lymphocytic leukemia; the trial status is …
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Clinico-hematological and Molecular Characteristics of Chronic Lymphocytic Leukemia Patients
Clinical trial update describing clinico-hematological and molecular characteristics of Chronic Lymphocytic Leukemia patients; the study is …
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CLINICAL_TRIALS other · 2025-09-08Clinical Trial Update: A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001) [Phase 1, Phase 2]
This clinical trial update indicates that Nemtabrutinib (MK-1026) is being studied for relapsed or refractory hematologic malignancies in a …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 clinical trial update describes modified CD19/CD20 CAR-T cells for recurrent or refractory B-cell lymphoma or chronic lymphocytic …
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Notch 1 Mutation in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patient
This ClinicalTrials.gov entry (NCT07157579) from Sohag University notes a study on Notch 1 mutation in chronic lymphocytic leukemia and non-…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Ibrutinib as Early Therapy in Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 study evaluating ibrutinib as early therapy for chronic lymphocytic leukemia and small lymphocytic leukemia; the trial is completed …
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Feasibility of a Whole-Food, Plant-Based Diet for Patients With Low-Risk Chronic Lymphocytic Leukemia (CLL) [NA]
This completed feasibility trial evaluated a whole-food, plant-based diet in patients with low-risk chronic lymphocytic leukemia (Stage A0),…