Lung Allograft Dysfunction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Targeting Interferon Gamma With Emapalumab to Lung Transplant Recipients With Interferon Gamma-high Acute Lung Allograft Dysfunction [Phase 2]
A Phase 2 clinical trial is evaluating emapalumab (anti-IFN-γ) for lung transplant recipients with interferon gamma-high acute lung allograf…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients [Phase 2]
A Phase 2 clinical trial is evaluating belumosudil to prevent chronic lung allograft dysfunction in high-risk lung transplant recipients and…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome. [Phase 2]
Phase 2 trial update for LAM-001 in lung transplant recipients with bronchiolitis obliterans syndrome and chronic lung allograft dysfunction…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction [Phase 3]
A Phase 3 clinical trial evaluating the effectiveness of belumosudil tablets in adults with chronic lung allograft dysfunction after lung tr…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD
This clinical trial is evaluating plasma and radiologic biomarkers of response to extracorporeal photopheresis in lung transplant recipients…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Prediction of Lung Transplant Outcome [NA]
An active-not-recruiting clinical trial focused on predicting outcomes after lung transplantation, including graft dysfunction and chronic a…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after single-…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Assessment of Chronic Lung Allograft Dysfunction Using Single-breath & Multi-breath Hyperpolarized Xenon-129 MRI
A clinical trial update noting the termination of a study evaluating single-breath and multi-breath Hyperpolarized Xenon-129 MRI to assess c…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: HP 129Xe MRI for Evaluation of CLAD in Lung Transplant Recipients [Phase 2]
Phase 2 study evaluating HP 129Xe MRI for assessment of chronic lung allograft dysfunction in lung transplant recipients has been terminated…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2) [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after double-lung tr…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Quantitative Parameters of HLA-DQ Antibodies in Lung Transplantation
A completed clinical trial update reporting quantitative parameters of HLA-DQ antibodies in lung transplantation, with relevance to antibody…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Unraveling Mechanism of Action of Extracorporeal Photopheresis in Heart and Lung Transplant Patients
This completed clinical trial examines the mechanism of action of extracorporeal photopheresis in heart and lung transplant recipients. It a…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Chronic Lung Allograft Dysfunction MRI Study [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating MRI-based assessment for Chronic Lung Allograft Dysfunction is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: Safety of Endobronchial Mesenchymal Stromal Cells in the Treatment of Chronic Lung Allograft Dysfunction [Phase 1]
A Phase 1 trial is evaluating the safety of endobronchial mesenchymal stromal cells for chronic lung allograft dysfunction and is currently …
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Trajectories of FEV1 After Lung Transplantation
A clinical trial update shows that a study on trajectories of FEV1 after lung transplantation is currently enrolling by invitation. The spon…
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Trial of Bone-marrow Derived Mesenchymal Stromal Cells (MSC) for New Onset Chronic Lung Allograft Dysfunction [Phase 2]
Phase 2 trial evaluating bone-marrow derived mesenchymal stromal cells for new onset chronic lung allograft dysfunction has been completed.
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CLINICAL_TRIALS trial_result · 2022-08-17Clinical Trial Update: Studying the Treatment Effect of Pirfenidone in Chronic Lung Allograft Dysfunction (STOP-CLAD) [Phase 2]
Phase 2 trial studying pirfenidone for chronic lung allograft dysfunction in lung transplant recipients was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: European Trial of Pirfenidone in BOS, A European Multi-center Study [Phase 2, Phase 3]
Phase 2/3 European trial of pirfenidone in Bronchiolitis Obliterans related to lung transplant (CLAD) has completed.
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Evaluation of Electrical Impedance Tomography for the Diagnosis of Chronic Rejection in Lung Transplants Recipients [NA]
Clinical trial completion evaluating electrical impedance tomography for diagnosing chronic rejection in heart-lung transplant recipients.
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction
A completed clinical trial evaluating breath volatile organic compound patterns in lung transplant patients with chronic lung allograft dysf…