Daily Headache

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches [Phase 3]

  A multi-center Phase 3 randomized controlled trial is evaluating intravenous ketamine for efficacy and safety in chronic daily headaches and…

• CLINICAL_TRIALS research · 2025-07-23
  Clinical Trial Update: Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics

  A clinical trial update on a Stanford study investigating headache chronification using imaging, deep phenotyping, and proteomics; the study…

• CLINICAL_TRIALS trial_result · 2023-06-15
  Clinical Trial Update: Effect of Intranasal Oxytocin on Headache in Chronic Daily Headache [NA]

  A completed clinical trial investigating intranasal oxytocin for reducing headache in chronic daily headache; results posted in 2023.

• CLINICAL_TRIALS trial_result · 2021-12-29
  Clinical Trial Update: Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines [Phase 4]

  Phase 4 trial comparing sphenopalatine ganglion nerve block to amitriptyline (Elavil) for transformed migraines was terminated, with results…

• CLINICAL_TRIALS trial_result · 2017-05-04
  Clinical Trial Update: Propofol Injection for Daily Headache [Phase 2]

  A Phase 2 trial evaluating propofol injections for chronic daily headache and analgesic rebound headache has completed.

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• CLINICAL_TRIALS trial_result · 2017-05-02
  Clinical Trial Update: Yoga Training for Returning Veterans With Headache [NA]

  A UCLA-sponsored clinical trial evaluating yoga training for returning veterans with post-traumatic headache and chronic daily headache has …

• CLINICAL_TRIALS trial_result · 2017-02-23
  Clinical Trial Update: Nutrition for Chronic Daily Headache [NA]

  A completed clinical trial evaluating nutrition for chronic daily headache; no specific results are provided in the update.

• CLINICAL_TRIALS trial_result · 2016-03-09
  Clinical Trial Update: Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents [NA]

  A completed UCLA-sponsored clinical trial evaluated peer mentorship as an intervention to promote effective pain self-management in adolesce…

• CLINICAL_TRIALS trial_result · 2011-05-19
  Clinical Trial Update: Evaluation of the Effectiveness of Topiramate in Preventing the Transformation From Episodic Migraine to Chronic Daily Headache. [Phase 4]

  Phase 4 trial assessing whether topiramate can prevent episodic migraine from converting into chronic daily headache; the study has complete…

• CLINICAL_TRIALS trial_result · 2010-10-29
  Clinical Trial Update: Do Patients With Chronic Daily Headache Have Continuous Headache or Moments of Headache Relief?

  This clinical trial update reports results from a completed study investigating whether patients with Chronic Daily Headache experience cont…

• CLINICAL_TRIALS trial_result · 2009-07-02
  Clinical Trial Update: Atkins Diet for Difficult-to-Control Headaches in Teenagers [Phase 1]

  A Phase 1 clinical trial evaluating the Atkins Diet for teenagers with chronic daily headache has completed.