Choroideremia
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CLINICAL_TRIALS trial_result · 2026-07-06Clinical Trial Update: Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa [Phase 3]
Phase 3 long-term safety and efficacy follow-up study for BIIB111 in choroideremia and BIIB112 in X-linked retinitis pigmentosa has complete…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Study to Evaluate Safety of RTx-015 Injection in Retinitis Pigmentosa or Choroideremia Patients (ENVISION) [Phase 1]
ENVISION is a Phase 1 trial evaluating the safety of RTx-015 injection in patients with retinitis pigmentosa or choroideremia; the study is …
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) [Phase 1, Phase 2]
An early-phase (Phase 1/2) dose-escalation study is investigating intravitreal KIO-301 for Retinitis pigmentosa and choroideremia; the trial…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa [Phase 3]
This clinical trial update outlines long-term safety and efficacy follow-up for BIIB111 in choroideremia and BIIB112 for X-linked retinitis …
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia [Phase 1]
Phase 1 dose-escalation study evaluating intravitreal 4D-110 in patients with choroideremia.
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: High Resolution Retinal Imaging
A University of Pennsylvania-sponsored clinical trial using high-resolution retinal imaging is currently recruiting participants for several…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Inherited Retinal Degenerative Disease Registry
A Foundation Fighting Blindness–sponsored inherited retinal degenerative disease registry is currently recruiting participants to collect in…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration
This clinical trial update describes an observational study to assess endpoint feasibility and measurement properties in patients with retin…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Longitudinal Study of a Bionic Eye
Clinical trial update for a longitudinal study of a bionic eye, enrolling by invitation to investigate treatment for retinal degenerations.
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CLINICAL_TRIALS trial_result · 2023-12-07Clinical Trial Update: Efficacy and Safety of BIIB111 for the Treatment of Choroideremia [Phase 3]
Phase 3 trial updates the efficacy and safety of BIIB111 for treating choroideremia; results have been posted after completion.
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations [Phase 1, Phase 2]
Phase 1/2 safety and dose-escalation study of AAV2-hCHM for CHM-related choroideremia completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111 [Phase 2]
A Phase 2 safety study of retinal gene therapy BIIB111 for choroideremia has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: An Open Label Clinical Trial of Retinal Gene Therapy for Choroideremia [Phase 1, Phase 2]
An open-label Phase 1/2 clinical trial of retinal gene therapy for choroideremia has been completed.
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CLINICAL_TRIALS trial_result · 2021-08-05Clinical Trial Update: REP1 Gene Replacement Therapy for Choroideremia [Phase 2]
Phase 2 clinical trial update for REP1 gene replacement therapy in choroideremia has been completed.
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CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: THOR - Tübingen Choroideremia Gene Therapy Trial [Phase 2]
Phase 2 gene therapy trial for choroideremia completed, updating on THOR study in Tübingen.
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CLINICAL_TRIALS trial_result · 2019-07-29Clinical Trial Update: Choroideremia Gene Therapy Clinical Trial [Phase 2]
Phase 2 clinical trial update for a choroideremia gene therapy; study completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Gene Therapy for Blindness Caused by Choroideremia [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial update reports on a gene therapy being assessed for blindness caused by choroideremia, conducted by the…
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: Restoring Vision With the Intelligent Retinal Implant System (IRIS V1)in Patients With Retinal Dystrophy [NA]
A completed trial update on restoring vision with the Intelligent Retinal Implant System (IRIS V1) in patients with retinal dystrophy, inclu…
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Pilot Study of a Suprachoroidal Retinal Prosthesis [NA]
This update notes the completion of a pilot study of a suprachoroidal retinal prosthesis.
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia [Phase 1, Phase 2]
This clinical trial update reports on the short-term effects of simvastatin on the vision of males with choroideremia (Phase 1/Phase 2).
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CLINICAL_TRIALS research · 2010-03-03Clinical Trial Update: IRIS PILOT - Extended Pilot Study With a Retinal Implant System [NA]
An update on the IRIS PILOT Extended Pilot Study of a retinal implant system. The trial status is currently unknown.