Chorioamnionitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: IL-6 and Lactates in Cord Blood and Neonatal Outcomes
A clinical trial registry entry studying IL-6 and lactate levels in cord blood to predict neonatal outcomes in pregnancies with fetal infect…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Amniotic Fluid & the Preterm Gut
Recruitment is ongoing for a study examining amniotic fluid and the preterm gut. The study targets several associated neonatal conditions, i…
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CLINICAL_TRIALS withdrawal · 2025-08-03Clinical Trial Update: Treatment of Chorioamnionitis After Delivery [NA]
The clinical trial 'Treatment of Chorioamnionitis After Delivery' (NCT00814905) has been withdrawn.
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Comparing Infectious Morbidity Among Women With Meconium-stained Amniotic Fluid at Term, Between Those Treated With Prophylactic Antibiotics Zinacef vs. Placebo [NA]
This clinical trial compares prophylactic Zinacef (cefuroxime) vs placebo to prevent infectious morbidity in term pregnancies with meconium-…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT) [Phase 4]
A Phase 4 randomized trial is planned to compare dipyrone (metamizole) with acetaminophen for intrapartum fever, including chorioamnionitis …
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Selective Use of Antibiotics in Neonates Born to Mothers With Suspected Chorioamnionitis
Completed clinical trial evaluating selective antibiotic use in neonates born to mothers with suspected chorioamnionitis. The study was spon…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy [Phase 2]
Phase 2 trial completion evaluating maternal treatment of bacterial vaginosis during pregnancy and its effects on preterm birth, birth weigh…
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CLINICAL_TRIALS withdrawal · 2018-10-23Clinical Trial Update: Intrapartum Fever: Antibiotics Versus no Treatment [Phase 4]
A Phase 4 trial evaluating antibiotics versus no treatment for intrapartum fever has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-10-10Clinical Trial Update: N-acetylcysteine in Intra-amniotic Infection/Inflammation [Phase 1, Phase 2]
Clinical trial update on N-acetylcysteine for intra-amniotic infection/inflammation (labor premature, PPROM) spanning Phase 1 and Phase 2; s…
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Treatment Utility of Postpartum Antibiotics in Chorioamnionitis [Phase 4]
Phase 4 trial evaluating whether postpartum antibiotics reduce endometritis in women with chorioamnionitis; the study was terminated and res…
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: Intrapartum Study of Sterile and Clean Gloves [NA]
A completed clinical trial comparing sterile versus clean gloves used during intrapartum care, sponsored by the Medical University of South …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Infant Immune Response to Bacterial Infection
This entry notes the completion of a NICHD-sponsored clinical trial investigating how prematurity and histologic chorioamnionitis affect the…
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CLINICAL_TRIALS other · 2017-05-12Clinical Trial Update: Closure of Skin in ChorioAmnionitis Research Pilot Study [NA]
A pilot study on skin closure in chorioamnionitis has been closed; current status of the trial is unknown.
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis [Phase 2, Phase 3]
A clinical trial comparing ampicillin/sulbactam to ampicillin/gentamicin for chorioamnionitis completed Phase 2 and Phase 3, with results po…
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CLINICAL_TRIALS trial_result · 2016-12-19Clinical Trial Update: Chorioamnionitis and Proinflammatory S100A12
A completed clinical trial sponsored by the Catholic University of the Sacred Heart studied chorioamnionitis affecting fetus or newborn and …
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CLINICAL_TRIALS trial_result · 2016-11-28Clinical Trial Update: Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term [Phase 2, Phase 3]
Phase 2/3 trials evaluating antibiotic prophylaxis for prelabor rupture of membranes at term have completed enrollment. The study examines m…
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety of N-acetylcysteine in maternal chorioamnionitis with potential brain injury outcomes; study comp…
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Perinatal Infections in Pakistan
This completed clinical trial in Pakistan, sponsored by NICHD Global Network for Women's and Children's Health, studied perinatal infections…
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CLINICAL_TRIALS trial_result · 2013-07-19Clinical Trial Update: Kinetics of Inflammation Markers in Maternal Plasma: Study of the Correlation With the Diagnosis of Chorioamnionitis in Women Hospitalized for Spontaneous Rupture of the Fetal Membranes [NA]
A clinical trial investigating the kinetics of inflammation markers in maternal plasma to diagnose chorioamnionitis in women with spontaneou…
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CLINICAL_TRIALS research · 2013-01-29Clinical Trial Update: Early Identification of Brain Insult in Chorioamnionitis
A clinical trial update from Sheba Medical Center about a study aiming to identify early brain insult in infants exposed to chorioamnionitis…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis [NA]
This clinical trial update reports on the comparison of once-daily versus 8-hour dosing of gentamicin for intrapartum chorioamnionitis, with…
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CLINICAL_TRIALS research · 2006-11-30Clinical Trial Update: Changes in Blood Flow in MCA of Fetuses to Mothers Having Clinical Chorioamnionitis
A clinical trial is studying changes in fetal middle cerebral artery blood flow in pregnancies with clinical chorioamnionitis; the current s…