Charcot-marie-tooth Disease
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for IPSC Generation and Biobanking
This clinical trial update describes the collection of biological samples from Charcot-Marie-Tooth disease patients and healthy controls to …
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: EVALUATION OF SERUM INFLAMMATORY CYTOKINE CONCENTRATION IN HEREDITARY SENSITIVOMOTOR NEUROPATHIES [NA]
This clinical trial update notes the completion of a study evaluating serum inflammatory cytokine concentrations in Charcot-Marie-Tooth dise…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Quantification of Nerve Stiffness in Neuropathies [NA]
A completed clinical trial update investigating quantification of nerve stiffness in inflammatory neuropathies including Chronic Inflammator…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
A clinical trial update reports completion of a genetics study on pediatric-onset motor neuron and neuromuscular diseases, including spinal …
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: The Impact of Charcot-Marie-Tooth Disease in the Real World
This entry notes the completion of a real-world clinical trial evaluating the impact of Charcot-Marie-Tooth disease.
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Natural History Study for Charcot Marie Tooth Disease
A clinical trial update indicates a natural history study for Charcot-Marie-Tooth disease is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: Impact of Sensory, Motor and Vestibular Deficit on the Postural Stability of CMT Patients
A clinical trial sponsored by IRCCS San Raffaele is recruiting to study how sensory, motor, and vestibular deficits affect postural stabilit…
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients [Phase 3]
Phase III trial evaluating PXT3003 for Charcot-Marie-Tooth Disease is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease [Phase 2]
Phase 2 trial of ACE-083 in Charcot-Marie-Tooth Disease was terminated; results were posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Extension Study to Evaluate the Long-Term Effects of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) and Charcot-Marie Tooth (CMT) Disease Types 1 and X (CMT1 and CMTX) [Phase 2]
Phase 2 extension study evaluating long-term effects of ACE-083 in facioscapulohumeral muscular dystrophy (FSHD) and Charcot-Marie-Tooth dis…
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study [Phase 2]
Phase 2 open-label pilot study of MD1003 (serendem) in demyelinating neuropathies completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)
A completed clinical trial update detailing the Disability Severity Index (DSI) and HMSN-R-ODS scales used to assess disability in Charcot-M…
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CLINICAL_TRIALS research · 2019-01-22Clinical Trial Update: Effect of Orthoses and Underfoot Vibration on Balance in Neuropathy
This clinical trial update describes a study evaluating whether foot orthoses and underfoot vibration affect balance in people with Charcot-…
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth Disease [NA]
The document reports a completed feasibility study (BALTiC) evaluating home-based balance training for people with Charcot-Marie-Tooth disea…
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CLINICAL_TRIALS trial_result · 2018-03-26Clinical Trial Update: Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease [Phase 2]
A Phase 2 clinical trial evaluating mexiletine for reducing muscle cramps in Charcot-Marie-Tooth disease has completed and results were post…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies
A completed clinical trial update assessing patient-reported outcomes measures for carpal tunnel therapies in patients with inherited neurop…
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Diffusion Tensor Imaging in Chronic Inflammatory Demyelinating Polyneuropathy (PIDC)
The study evaluating diffusion tensor imaging in chronic inflammatory demyelinating polyneuropathy and Charcot-Marie-Tooth disease has compl…
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CLINICAL_TRIALS research · 2017-06-14Clinical Trial Update: An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients
A completed clinical trial analysis (NCT02429947) examines which symptomatic domains are most relevant to people with Charcot-Marie-Tooth di…
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CLINICAL_TRIALS research · 2016-12-01Clinical Trial Update: Charcot-Marie-Tooth Disease (CMT) Infant Scale (INC-6611)
An update on a clinical trial evaluating the Charcot-Marie-Tooth Disease Infant Scale (INC-6611); current status is unknown.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Study of Electrical Impedance Myography (EIM) in ALS
This update reports on the completed clinical trial evaluating Electrical Impedance Myography (EIM) in amyotrophic lateral sclerosis and rel…
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CLINICAL_TRIALS research · 2015-01-30Clinical Trial Update: Survey of Current Management of Orthopaedic Complications in CMT Patients
A completed observational survey by University College London Hospitals examining current management of orthopedic complications in Charcot-…
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CLINICAL_TRIALS research · 2014-03-26Clinical Trial Update: Development and Validation of a Disability Severity Index for CMT
Development and validation of a Disability Severity Index to quantify functional impairment in Charcot-Marie-Tooth disease.
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CLINICAL_TRIALS trial_result · 2013-08-08Clinical Trial Update: Evaluation of the Analgesic Efficiency of the Transcutaneous Neurostimulation in the Charcot Syndrome Marie Tooth on the Pains of Lower Limbs [NA]
A clinical trial update evaluating the analgesic effectiveness of transcutaneous neurostimulation for lower-limb pain in Charcot-Marie-Tooth…
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CLINICAL_TRIALS trial_result · 2013-07-15Clinical Trial Update: Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the effects of Coenzyme Q10 on Charcot-Marie-Tooth disease has completed.
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CLINICAL_TRIALS research · 2011-02-04Clinical Trial Update: Treadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot-Marie-Tooth Neuropathy Type 1A (CMT1A) [Phase 2, Phase 3]
This entry reports a Phase 2/Phase 3 clinical trial update for the TreSPE rehabilitation program in Charcot-Marie-Tooth disease type 1A, wit…