Cerebrospinal Fluid Leak
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Efficacy and Safety Evaluation of Absorbable and Moldable Skull Base Support Plates in Extended Endoscopic Endonasal Transsphenoidal Surgery: A Prospective, Randomized, Controlled Study [Phase 2]
This Phase 2 randomized trial evaluates absorbable and moldable skull base support plates used during extended endoscopic endonasal transsph…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery [NA]
This document reports a recruiting clinical trial evaluating a novel RADA16 peptide hydrogel during endoscopic skull base surgery to assess …
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: CraniSeal Post Approval Study [Phase 4]
Phase 4 post-approval clinical trial update for CraniSeal. The study evaluating CraniSeal for cerebrospinal fluid leaks is currently recruit…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks [NA]
An ongoing clinical trial that is currently recruiting to compare internal nasal splint-supported free graft versus nasoseptal flap for endo…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: NoSeal Trial: Comparing Sealants Versus No Sealant for Preventing CSF Leak After Endonasal Skull Base Surgery [NA]
An ongoing clinical trial evaluating whether using sealants after endonasal skull base surgery reduces cerebrospinal fluid leaks compared wi…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: A Prospective, Randomized, Controlled Multi-center Study of ArtiFascia® Dural Repair Patch Compared With Commercially Available Dural Substitutes. To Evaluate the Safety and Effectiveness of ArtiFascia® in Subjects Requiring Dural Repair. [NA]
A multicenter randomized trial comparing ArtiFascia Dural Repair Patch with standard dural substitutes to evaluate safety and effectiveness …
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Safety and Efficacy Evaluation of ArtiFix® Sealant Graft in Subjects Requiring Dural Repair Following Neurosurgery [NA]
A planned clinical trial to evaluate the safety and efficacy of ArtiFix Sealant Graft for dural repair after neurosurgery, with study recrui…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Suturable DuraGen™ PMCF Study
This post-market clinical follow-up study evaluating Suturable DuraGen for preventing cerebrospinal fluid leaks has been completed.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Hemopatch Safety and Efficacy Evaluation Versus Standard Practice for Sealing the Dura in Cerebrospinal Fluid Leaks [NA]
Completed clinical trial evaluating Hemopatch versus standard practice for sealing the dura to prevent cerebrospinal fluid leaks. The evalua…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Evaluate the Safety and Efficacy of Dura Sealant Patch in Reducing CSF Leakage Following Elective Cranial Surgery [NA]
A completed clinical trial evaluating the safety and efficacy of the Dura Sealant Patch to reduce cerebrospinal fluid leaks after elective c…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage [NA]
A clinical trial at National Taiwan University Hospital is evaluating whether a polyglycolic acid mesh can prevent cerebrospinal fluid leaka…
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CLINICAL_TRIALS trial_result · 2023-07-14Clinical Trial Update: The Paediatric EVICEL® Neuro Study [Phase 3]
Phase 3 pediatric study of EVICEL for cerebrospinal fluid leak was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment [Phase 2]
Phase 2 randomized trial evaluating CT fluoroscopy-guided targeted autologous blood and fibrin glue patching for cerebrospinal fluid leaks; …
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Efficacy and Safety of FS VH S/D 500 S-apr (Tisseel) as an Adjunct to Sutured Dural Repair in Cranial Surgery [Phase 3]
Phase 3 trial evaluating FS VH S/D 500 S-apr (Tisseel) as an adjunct to sutured dural repair in cranial surgery for cerebrospinal fluid leak…
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CLINICAL_TRIALS withdrawal · 2019-02-12Clinical Trial Update: Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics [Phase 4]
A Phase 4 trial evaluating a sphenopalatine ganglion nerve block for postdural puncture headache (with cerebrospinal fluid leak) in obstetri…
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: The EVICEL® Neurosurgery Phase III Study [Phase 3]
Phase III study update for EVICEL in neurosurgery completed; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose [NA]
A completed clinical trial evaluating Cone Beam CT at lower dose for diagnosis in select ENT indications; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Mobilisation Algorithm After Incidental Durotomy [NA]
Clinical trial update on a mobilisation algorithm after incidental durotomy in patients with cerebrospinal fluid leak. The current status of…
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CLINICAL_TRIALS trial_result · 2016-08-24Clinical Trial Update: Value of Radionuclide Cisternography
The document reports on a completed clinical trial evaluating the usefulness of radionuclide cisternography for diagnosing cerebrospinal flu…
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: TASALL - TachoSil® Against Liquor Leak [Phase 3]
Phase 3 trial evaluating TachoSil for preventing cerebrospinal fluid leaks has completed, with results posted.