Central Nervous System Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab [Phase 2]
Phase 2 clinical trial evaluating oral pazopanib plus oral topotecan given in a metronomic antiangiogenic regimen for recurrent glioblastoma…
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CLINICAL_TRIALS trial_result · 2019-12-10Clinical Trial Update: A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors [Phase 2]
Phase 2 trial evaluating pomalidomide monotherapy in children and young adults with recurrent or progressive primary brain tumors, including…
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma [Phase 1, Phase 2]
Phase I/II trial comparing bevacizumab alone versus bevacizumab plus TPI-287 for recurrent glioblastoma; trial terminated with results poste…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: High-Dose Trivalent Influenza Vaccine in Inducing Immune Response Patients With Central Nervous System Tumors [Phase 1]
Phase 1 trial evaluating whether a high-dose trivalent influenza vaccine can induce an immune response in patients with central nervous syst…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Trivalent Influenza Vaccine in Preventing Flu in Patients With Central Nervous System Tumors
Completed clinical trial evaluating whether a trivalent influenza vaccine prevents influenza in patients with central nervous system neoplas…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors [Phase 2]
Phase 2 results update on Gefitinib for patients with recurrent or progressive brain and central nervous system tumors. The trial status is …
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas [NA]
A completed clinical trial evaluating radiation therapy or combination chemotherapy for progressive low-grade gliomas in patients, as report…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Interdisciplinary Rehabilitation of Patients With Glioma During Anti-cancer Treatment [NA]
A completed clinical trial assessing interdisciplinary rehabilitation for glioma patients during anti-cancer treatment.
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis [Phase 1]
Phase 1 clinical trial update on an imaging probe for use in cell and gene therapy trials targeting brain neoplasms and rheumatoid arthritis…
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CLINICAL_TRIALS research · 2016-07-19Clinical Trial Update: Retrospective Study of MRI in Pediatric Patients
This document reports a completed retrospective study evaluating MRI use in pediatric patients with central nervous system diseases, includi…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma [Phase 1]
This clinical trial update reports the completion of a Phase I study evaluating 5-fluorouracil in children and young adults with recurrent e…
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors [Phase 1]
A Phase 1 clinical trial assessing the combination of everolimus and bevacizumab in pediatric patients with recurrent solid tumors and CNS m…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors [Phase 1]
This document reports the completion of a Phase 1 trial evaluating combination chemotherapy plus gene therapy in patients with brain neoplas…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Cytochlor, Tetrahydrouridine, and External-Beam Radiation Therapy in Treating Patients With Cancer That Has Spread to the Brain [Phase 1]
A Phase 1 study evaluating Cytochlor and tetrahydrouridine with external-beam radiation therapy for brain and central nervous system tumors …
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma [Phase 1]
Phase 1 trial evaluating the safety and dosage of combining irinotecan and temozolomide in patients with recurrent primary malignant glioma …
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors [Phase 2]
A Phase 2 clinical trial evaluating radiation therapy for progressive or recurrent malignant brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors [Phase 2]
Phase 2 clinical trial evaluating temozolomide followed by radiation therapy in children with newly diagnosed malignant CNS tumors has compl…
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Coproporphyrine Isomers and Methotrexate Elimination
This completed clinical trial update investigates coproporphyrin isomer profiles and methotrexate elimination in patients with Central Nervo…
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CLINICAL_TRIALS withdrawal · 2012-06-11Clinical Trial Update: Perfusion Magnetic Resonance Imaging in Measuring the Growth of Blood Vessels in Newly Diagnosed Brain Tumors [NA]
The clinical trial investigating perfusion MRI to measure blood vessel growth in newly diagnosed brain tumors has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-04-27Clinical Trial Update: Safety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) Malignancy [Phase 1]
Phase 1 safety study of high-dose temozolomide in relapsed or refractory central nervous system malignancies has been terminated.
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CLINICAL_TRIALS trial_result · 2011-10-04Clinical Trial Update: Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor [Phase 2]
Phase 2 clinical trial evaluating irinotecan followed by radiation therapy and temozolomide in children with newly diagnosed brain tumors; s…
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CLINICAL_TRIALS trial_result · 2011-06-30Clinical Trial Update: Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors [Phase 1]
A Phase 1 trial of topotecan in young patients with neoplastic meningitis due to leukemia, lymphoma, or solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2011-03-28Clinical Trial Update: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Brain Cancer [Phase 1]
This Phase 1 trial evaluated chemotherapy followed by peripheral stem cell transplantation or bone marrow transplantation in patients with b…
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CLINICAL_TRIALS research · 2010-10-27Clinical Trial Update: CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan [Phase 2]
Phase 2 clinical trial update evaluating CT-322 with irinotecan for recurrent glioblastoma multiforme; sponsored by Adnexus (a Bristol-Myers…
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CLINICAL_TRIALS trial_result · 2010-06-11Clinical Trial Update: Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma [Phase 1]
This Phase 1 trial of gene therapy and chemotherapy in patients with advanced solid tumors and Non-Hodgkin lymphoma was terminated, with no …