Cancer
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CLINICAL_TRIALS trial_result · 2016-12-30Clinical Trial Update: The Sakakibara Health Integrative Profile Cohort Study
This document notes the completion of the Sakakibara Health Integrative Profile Cohort Study sponsored by the Sakakibara Heart Institute, fo…
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: Phase 2 Safety, Tolerability and Efficacy Study of CPI-613 in Cancer Patients [Phase 2]
The update indicates that the Phase 2 safety, tolerability, and efficacy study of CPI-613 in cancer patients has been terminated.
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer [Phase 3]
Phase 3 trial evaluating APF530 or Aloxi (palonosetron hydrochloride) in combination with dexamethasone to prevent chemotherapy-induced naus…
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients [Phase 1]
Completed Phase I dose-escalation trial of an allosteric AKT 1/2 inhibitor sponsored by Bayer in patients with cancer.
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CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety [Phase 1]
This Phase 1 study evaluated the effect of a single dose of NKTR-102 (etirinotecan pegol) on QTc interval and assessed pharmacokinetics and …
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents
Clinical trial update describing a study that uses catheter resistance monitoring to predict catheter-associated adverse events in children …
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CLINICAL_TRIALS trial_result · 2016-12-20Clinical Trial Update: RAPID-2. A Study to Evaluate the Effectiveness of Alternate Dosing of PROCRIT (Epoetin Alfa) in Maintaining Hemoglobin Levels in Patients With Chemotherapy Related Anemia [Phase 4]
The Phase 4 RAPID-2 trial evaluating alternate dosing of PROCRIT (epoetin alfa) to maintain hemoglobin in chemotherapy-induced anemia has be…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: A Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN) [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of an oxycodone/naloxone combination in Korean patients with chemotherapy-i…
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: The Copenhagen City Heart Study
A completed clinical trial update for the Copenhagen City Heart Study sponsored by Bispebjerg Hospital. The listed conditions include corona…
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Topical Sunscreen in Preventing Skin Rash in Patients Receiving Drugs Such as Erlotinib or Cetuximab for Cancer [Phase 3]
A Phase 3 trial evaluated whether topical sunscreen can prevent skin rash in cancer patients receiving EGFR inhibitors erlotinib or cetuxima…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: (Valerian) for Improving Sleep in Patients With Cancer Receiving Adjuvant Therapy [Phase 3]
Phase 3 trial evaluating valerian to improve sleep in cancer patients receiving adjuvant therapy has completed.
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: Web-based Study for Cancer Survivors [NA]
Completed web-based study for cancer survivors evaluating physical activity and dietary modification.
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CLINICAL_TRIALS research · 2016-11-25Clinical Trial Update: Assay Development for Cancer Biomarkers
A study update from King's College London on assay development for cancer biomarkers; no status or results are provided.
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CLINICAL_TRIALS research · 2016-11-18Clinical Trial Update: Blood Draw Validation for Ciprofloxacin Pharmacokinetic Research in Pediatric Cancer Patients [Phase 4]
Phase 4 update describing a validation study for blood sampling in ciprofloxacin pharmacokinetic research in pediatric cancer patients, incl…
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CLINICAL_TRIALS trial_result · 2016-11-11Clinical Trial Update: Polymorphisms in the Vitamin D System and Health
This clinical trial update reports completion of a study on polymorphisms in the vitamin D system and health outcomes, listing several condi…
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CLINICAL_TRIALS withdrawal · 2016-11-07Clinical Trial Update: Companion Study for Patients Who Completed Participation in a REGN2810 (Anti-PD-1) Clinical Study [Phase 1]
This notice describes a companion Phase 1 study for patients who completed participation in Regeneron's REGN2810 anti-PD-1 clinical trial, w…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Chemotherapy Toxicity Reduction Via Urea Cycle Support [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating whether supporting the urea cycle can reduce chemotherapy-relate…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Multiple Ascending Dose Study of R1507 in Patients With Advanced Solid Tumors. [Phase 1]
This Phase 1 multiple ascending dose study of R1507 in patients with advanced solid tumors has completed. The trial aimed to evaluate safety…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A First-In-Human Study of RO5503781 in Participants With Advanced Malignancies Except Leukemia [Phase 1]
This is a first-in-human Phase 1 study of RO5503781 in participants with advanced cancers excluding leukemia. The trial, sponsored by Hoffma…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Multiple Ascending Dose Study of the mTOR Inhibitor (RAD001) in Combination With R1507 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study to evaluate escalating doses of everolimus (RAD001) in combination with the IGF-1 receptor antibody R1507 in patients with adv…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5045337 in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial assessing RO5045337 in patients with solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5458640 in Patients With Advanced Solid Tumors [Phase 1]
Hoffmann-La Roche completed a Phase 1 study of RO5458640 in patients with advanced solid tumors (NCT01383733). The trial status is listed as…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5429083 in Patients With Metastatic and/or Locally Advanced, CD44-Expressing, Malignant Solid Tumors [Phase 1]
A Phase 1 study evaluating RO5429083 in patients with metastatic and/or locally advanced CD44-expressing malignant solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects [Phase 1]
Phase 1 study in healthy subjects to evaluate a formulation change and the effect of food on the bioavailability of ipatasertib (GDC-0068) s…
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CLINICAL_TRIALS trial_result · 2016-11-01Clinical Trial Update: A Multiple Ascending Dose Study of R1507 in Children and Adolescents With Advanced Solid Tumors. [Phase 1]
Roche's investigational antibody R1507 was studied in a phase 1 multiple ascending dose trial in children and adolescents with advanced soli…