Cancer
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CLINICAL_TRIALS safety_alert · 2025-12-24Clinical Trial Update: Risk of Reactivation of Occult Hepatitis B in Cancer Patients During Immunotherapy.
A clinical trial update warns of the risk of occult hepatitis B reactivation in cancer patients receiving immunotherapy, highlighting concer…
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CLINICAL_TRIALS safety_alert · 2025-05-25Clinical Trial Update: Benign Migratory Glossitis Associated With Antiangiogenic Drugs
A clinical trial update reports an association between antiangiogenic drugs and Benign Migratory Glossitis (Geographic Tongue) in cancer pat…
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EMA safety_alert · 2025-03-13Unregulated advanced therapy medicinal products pose serious risks to health
EMA warns that unregulated advanced therapy medicinal products pose serious health risks in the EU, including dendritic cell–based cancer th…
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EMA safety_alert · 2024-06-14Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 10-13 June 2024
PRAC started a safety review of metamizole and an investigation into potential links between CAR T-cell therapies and secondary cancers.
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EMA safety_alert · 2019-01-23No new patients should start treatment with Lartruvo after study shows cancer medicine does not prolong life
EMA advises that no new patients should start treatment with Larotrectinib? wait: article states Lartruvo (avelumab? actually Lartruvo is ol…
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EMA safety_alert · 2017-06-09PRAC concludes there is no evidence of a change in known risk of neutropenic enterocolitis with docetaxel
The EMA's Pharmacovigilance Risk Assessment Committee (PRAC) concluded there is no evidence of a change in the known risk of neutropenic ent…
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CLINICAL_TRIALS safety_alert · 2016-07-14Clinical Trial Update: Acute Pain Caused by Paclitaxel in Patients With Cancer
This update discusses acute pain and neurotoxicity observed with paclitaxel in cancer patients from a completed clinical trial.
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CLINICAL_TRIALS safety_alert · 2011-07-07Clinical Trial Update: Liver Function Test (LFT) Elevations in Cancer Patients and Users of Tyrosine Kinase Inhibitor (TKI) Drugs
A clinical trial update notes elevations in liver function tests among cancer patients and users of tyrosine kinase inhibitors, highlighting…
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CLINICAL_TRIALS safety_alert · 2010-09-24Clinical Trial Update: Maintenance Study on the Long Term Safety of XL999 [Phase 1]
A Phase 1 maintenance study evaluating the long-term safety of XL999 in patients with advanced cancer has completed.
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EMA safety_alert · 2010-02-18European Medicines Agency recommends contraindication for Regranex in patients with any pre-existing cancer
EMA recommends contraindicating Regranex (becaplermin) in patients with any pre-existing cancer.
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EMA safety_alert · 2008-06-26EMEA recommends a new warning for epoetins for their use in cancer patients
The EMA recommends a new warning for epoetins regarding their use in cancer patients to address safety concerns.