Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Safety, Pharmacokinetics (PK) of AKT and MEK Combination [Phase 1]
This Phase 1 trial reports safety and pharmacokinetic data for a combination of an AKT inhibitor and a MEK inhibitor in cancer patients.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Bioavailability and Food Effect of the Original Gelatin Formulation and Two New Formulations of Afuresertib in Normal Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetic study evaluating bioavailability and the effect of food on the original gelatin formulation and two new formulations…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors [Phase 1]
This Phase I study assesses the safety, pharmacokinetics, and pharmacodynamics of GSK2118436 (dabrafenib) in patients with solid tumors.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Determination of the Absolute Bioavailability of GSK2118436 Following a Single Oral Dose Co-Administered With an Intravenous Radiolabelled Microtracer of GSK2118436 in Subjects With BRAF Mutant Solid Tumors [Phase 1]
Phase 1 study update evaluating the absolute oral bioavailability of dabrafenib (GSK2118436) when co-administered with an intravenous radiol…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: GSK1120212 Food-effect Study [Phase 1]
Phase 1 food-effect study of GSK1120212 (trametinib) in cancer has been completed. The study evaluated whether food intake affects the drug'…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: A Study to Determine the Relative Bioavailability of the MEK Inhibitor, Trametinib, in Subjects With Solid Tumor Malignancies [Phase 1]
A Phase 1 study completed to determine the relative bioavailability of the MEK inhibitor trametinib in subjects with solid tumor malignancie…
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: A Study to Look at the Electrical Activity of the Heart in Subjects With Solid Tumor Cancers, Before and After Receiving the Study Treatment, GSK1120212 [Phase 1]
A Phase 1 trial evaluating the effect of trametinib (GSK1120212) on cardiac electrical activity in patients with solid tumors, assessed befo…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: An Absorption, Distribution, Metabolism and Excretion (ADME) Study of Single Oral Dose [14C] GSK2118436 in Subjects With BRAF Mutant Solid Tumors [Phase 1]
Completed Phase 1 ADME study evaluating pharmacokinetics of a single oral dose of [14C] GSK2118436 (dabrafenib) in patients with BRAF-mutant…
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CLINICAL_TRIALS withdrawal · 2017-11-09Clinical Trial Update: Dexamethasone in Preventing Hearing Loss in Patients Receiving Cisplatin [NA]
A clinical trial evaluating dexamethasone to prevent cisplatin-induced hearing loss in cancer patients has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: Physical Activity Advices to Prevent Loss of Autonomy in Cancer Treated Elderly Patients. An Intervention Randomized Study [NA]
A randomized intervention study assessing whether providing physical activity advice can prevent loss of autonomy in elderly cancer patients…
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: Impact of Elimination or Reduction of Dietary Animal Proteins on Cancer Progression and Survival - A Pilot Study
A completed pilot trial evaluating whether eliminating or reducing dietary animal proteins affects cancer progression and survival.
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function [Phase 1]
A Phase 1 pharmacokinetic study evaluating AMG 386 (trebananib) in cancer patients with normal and impaired renal function to assess how kid…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Pharmacokinetics and Metabolism Study in Healthy Male Participants [Phase 1]
Phase 1 pharmacokinetics and metabolism study conducted in healthy male participants sponsored by Bristol-Myers Squibb; the study has comple…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: A Psycho-educational Intervention for Symptom Cluster Management [NA]
Hanoi Medical University conducted a psycho-educational intervention trial for symptom cluster management in cancer patients. The trial stat…
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CLINICAL_TRIALS research · 2017-11-06Clinical Trial Update: Involvement of Patients and Relatives in the Course of Cancer Disease [NA]
A completed study examining how patients and their relatives are involved in the course of cancer during rehabilitation.
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Smart-phone Application to Promote Medication Adherence in Adolescents and Young Adults (AYA) With Cancer
This clinical trial update reports the completion and posting of results for a study evaluating a smartphone app designed to promote medicat…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Analgesia for Laparotomy in Cancer Patients: Quadratus Lumborum Block [NA]
A clinical trial evaluating quadratus lumborum block analgesia for laparotomy in cancer patients has completed.
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Increasing Implementation of Evidence-based Interventions at Low-wage Worksites [NA]
Clinical trial update indicating that the study on increasing implementation of evidence-based interventions at low-wage worksites has compl…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Advanced MRI Sequences for Radiation Therapy Treatment Planning
This completed clinical trial evaluated advanced MRI sequences to improve radiation therapy treatment planning. The results were posted on 2…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: American Ginseng in Treating Patients With Cancer-Related Fatigue [NA]
Update on a trial testing American ginseng for cancer-related fatigue in adults.
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: Methadone Associated With Morphine for Cancer Pain [NA]
A clinical trial update describes a study of using methadone in combination with morphine to treat cancer-related pain, with the current sta…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Assessing the Efficacy of a Psychosocial Intervention Program for Siblings of Children With Cancer [NA]
This clinical trial update notes the completion of a study evaluating a psychosocial intervention program for siblings of children with canc…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Mitochondrial Respiratory Function in Mammalian Skeletal Muscle
UTMB Galveston sponsored a study on mitochondrial respiratory function in mammalian skeletal muscle investigating cancer and cachexia. The t…
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Diabetes Prevention Program Outcomes Study [Phase 3]
Phase 3 trial update for the Diabetes Prevention Program Outcomes Study (DPPOS) with results posted in 2017.
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CLINICAL_TRIALS research · 2017-10-24Clinical Trial Update: A Study to Assess the Efficacy and Safety of Eltrombopag as a Rescue of Isolated Chemotherapy-induced Thrombocytopenia [Phase 3]
This update covers a Phase 3 study evaluating eltrombopag as rescue therapy for isolated chemotherapy-induced thrombocytopenia in patients w…