Cancer

• CLINICAL_TRIALS trial_result · 2017-08-03
  Clinical Trial Update: Romanian-Swiss Research Programme IZERZO

  The Romanian-Swiss IZERZO clinical trial program has completed. It is sponsored by the Cantonal Hospital of St. Gallen and studied patients …

• CLINICAL_TRIALS trial_result · 2017-08-02
  Clinical Trial Update: A Study To Test The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer Patients [Phase 1]

  Phase 1 study to evaluate how PF-00299804 affects the pharmacokinetics of dextromethorphan in cancer patients. The trial is completed and re…

• CLINICAL_TRIALS trial_result · 2017-08-01
  Clinical Trial Update: Individual Dose-escalated Bi-daily Subcutaneously (sc) Ghrelin in Cancer Cachexia: a Phase I/II Study [Phase 1, Phase 2]

  Phase I/II clinical trial evaluating dose-escalated subcutaneous ghrelin for cancer cachexia has completed. The study enrolled patients with…

• CLINICAL_TRIALS trial_result · 2017-07-31
  Clinical Trial Update: A Dose Escalation Study of the Safety and Pharmacokinetics of GSK1363089 (Formerly XL880) Administered Orally to Subjects With Solid Tumors [Phase 1]

  Phase 1 dose-escalation study evaluating the safety and pharmacokinetics of the oral agent GSK1363089 (XL880) in subjects with solid tumors;…

• CLINICAL_TRIALS trial_result · 2017-07-28
  Clinical Trial Update: Cancer and Disorders of Cognitive Functions and Quality of Life: "Cognitive Rehabilitation in Patients Suffering From Cancer and Treated With Chemotherapy" [NA]

  The document reports the completion of a clinical trial evaluating cognitive rehabilitation for cancer patients who received chemotherapy.

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• CLINICAL_TRIALS trial_result · 2017-07-26
  Clinical Trial Update: Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors [Phase 1]

  Phase 1 clinical trial update reporting safety and pharmacology data for SNX-5422 in combination with carboplatin and paclitaxel in patients…

• CLINICAL_TRIALS trial_result · 2017-07-26
  Clinical Trial Update: Demonstration of the "SPECT/CT System With CZT Detectors" Imaging Performance in a Clinical Setting [NA]

  This clinical trial update reports the completed demonstration of a SPECT/CT system with CZT detectors in a clinical cancer setting. It focu…

• CLINICAL_TRIALS trial_result · 2017-07-24
  Clinical Trial Update: Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam [Phase 1]

  A Phase 1 study evaluating whether dabrafenib changes the pharmacokinetics of rosuvastatin and midazolam after a single dose; the trial stat…

• CLINICAL_TRIALS trial_result · 2017-07-24
  Clinical Trial Update: A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors [Phase 1]

  A completed Phase 1 study evaluating the safety and pharmacokinetics of KTN3379 in adults with advanced tumors.

• CLINICAL_TRIALS trial_result · 2017-07-21
  Clinical Trial Update: Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With Cancer [Phase 2]

  Phase 2 trial comparing ceftazidime-avibactam to standard of care in febrile neutropenic adults with cancer was terminated; results were pos…

• CLINICAL_TRIALS trial_result · 2017-07-21
  Clinical Trial Update: Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors [Phase 3]

  Phase 3 trial evaluating memantine to prevent cognitive/functional side effects in patients with brain metastases undergoing whole-brain rad…

• CLINICAL_TRIALS trial_result · 2017-07-21
  Clinical Trial Update: Effect of Sipjeondaebo-tang for Cancer Related Anorexia in Cancer Patients [NA]

  This update notes a completed clinical trial evaluating Sipjeondaebo-tang for cancer-related anorexia in cancer patients.

• CLINICAL_TRIALS trial_result · 2017-07-17
  Clinical Trial Update: Mindfulness Based Stress Reduction: Supportive Treatment for Adult Patients With Cancer and Their Partners [NA]

  The Mindfulness Based Stress Reduction trial for adult cancer patients and their partners has completed. The clinical trial status is finish…

• CLINICAL_TRIALS trial_result · 2017-07-12
  Clinical Trial Update: Phase I, Dose-escalation Trial of BAY1187982 in Subjects With Advanced Solid Tumors Known to Express Fibroblast Growth Factor Receptor 2 (FGFR2) [Phase 1]

  A Phase I dose-escalation trial of BAY1187982 in FGFR2-expressing advanced solid tumors has been terminated.

• CLINICAL_TRIALS trial_result · 2017-07-11
  Clinical Trial Update: Open-label, Single Arm, Tumor Imaging and Dosimetry Study of I-124 PGN650 in Advanced Solid Tumors [EARLY_Phase 1]

  An early-phase, open-label, single-arm imaging and dosimetry study of the radiolabeled agent I-124 PGN650 in patients with advanced solid tu…

• CLINICAL_TRIALS trial_result · 2017-07-06
  Clinical Trial Update: Tinzaparin for Primary Treatment and Extended Secondary Prophylaxis of Venous Thromboembolism in Patients With Cancer [Phase 2]

  Phase 2 trial of tinzaparin for primary treatment and extended secondary prophylaxis of venous thromboembolism in cancer patients was termin…

• CLINICAL_TRIALS trial_result · 2017-07-02
  Clinical Trial Update: Effect of Tai Chi Vs. Structured Exercise on Physical Fitness and Stress in Cancer Survivors [Phase 2]

  Phase 2 trial comparing Tai Chi to structured exercise in cancer survivors evaluated effects on physical fitness and stress; the study is sp…

• CLINICAL_TRIALS trial_result · 2017-07-02
  Clinical Trial Update: Phase I Study of HeFi-1 to Treat Cancers With CD30 Protein [Phase 1]

  A Phase I trial of HeFi-1 for cancers expressing CD34? expressing CD30? Wait: The document states CD30 proteins; the summary is updated here…

• CLINICAL_TRIALS trial_result · 2017-07-02
  Clinical Trial Update: SNX-5422 to Treat Solid Tumor Cancers and Lymphomas [Phase 1]

  Phase 1 trial results for SNX-5422 in solid tumors and lymphomas have completed.

• CLINICAL_TRIALS trial_result · 2017-07-02
  Clinical Trial Update: A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing HIF-1a [Phase 1]

  This Phase 1 pilot trial evaluated the safety, tolerability, and preliminary activity of oral topotecan in patients with refractory advanced…

• CLINICAL_TRIALS trial_result · 2017-07-02
  Clinical Trial Update: Characterization of the Pharmacokinetics of Oral Selenium Compounds in Humans Before and Following Supplementation

  A completed clinical trial characterizes the pharmacokinetics of oral selenium compounds in humans before and after supplementation.

• CLINICAL_TRIALS trial_result · 2017-06-29
  Clinical Trial Update: Comparison of Prophylactic Antiviral Efficacy in Patients Undergoing Chemotherapy: Entecavir Versus Lamivudine [Phase 3]

  A completed Phase 3 trial comparing entecavir to lamivudine for antiviral prophylaxis in patients undergoing chemotherapy. The study include…

• CLINICAL_TRIALS trial_result · 2017-06-28
  Clinical Trial Update: Use of Propranolol to Reduce FDG Uptake in Brown Adipose Tissue in Pediatric Cancer Patients PET Scans

  A completed pediatric cancer trial evaluated the use of propranolol to reduce FDG uptake in brown adipose tissue during PET scans, potential…

• CLINICAL_TRIALS trial_result · 2017-06-26
  Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-012/KEYNOTE-012) [Phase 1]

  Phase 1 study of pembrolizumab (MK-3475) in advanced solid tumors has completed with posted results.

• CLINICAL_TRIALS trial_result · 2017-06-23
  Clinical Trial Update: Dose Escalation Study of Gemcitabine and ON 01910.Na in Solid Tumors [Phase 1]

  Completed Phase 1 dose-escalation trial evaluating the combination of gemcitabine and ON-01910.Na in patients with solid tumors.