Bronchiolitis Obliterans
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 trial of ruxolitinib for early lung dysfunction after hematopoietic stem cell transplant was terminated.
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Extension Trial on Efficacy / Safety of L-CsA + SoC in Treating BOS in Post Single or Double Lung Transplant (BOSTON-3) [Phase 3]
The Phase 3 extension trial BOSTON-3 evaluating liposomal cyclosporine A added to standard of care for bronchiolitis obliterans syndrome in …
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP) [Phase 2]
A Phase 2 clinical trial BEBOP evaluating belumosudil for prevention and treatment of bronchiolitis obliterans syndrome and bronchiolitis ob…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Treatment of Pediatric Bronchiolitis Obliterans by Airway Basal Stem Cells [EARLY_Phase 1]
An early-phase 1 trial evaluating the safety and feasibility of treating pediatric bronchiolitis obliterans with airway basal stem cells. Th…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Prospective Evaluations of Infectious Complication in Lung Transplant Recipients
Completed clinical trial evaluating infectious complications in lung transplant recipients.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating nintedanib for bronchiolitis obliterans syndrome and bronchiolitis obliterans after hematopoietic stem cel…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after single-…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Hp129 Xenon Imaging and BOS in Lung Transplantation [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Hp129 Xenon Imaging for detecting or characterizing Bronchiolitis Obliterans in lung transplant recipien…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation [Phase 3]
Phase 3 trial evaluating inhaled fluticasone propionate with salmeterol versus placebo to improve respiratory function in children over six …
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2) [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after double-lung tr…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients
The TRANSPIRE study is a longitudinal pediatric HSCT cohort investigating transplant-related lung injuries. It is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Bronchial Epithelium of Children With Post-infectious Bronchiolitis Obliterans [NA]
A clinical trial evaluating bronchial epithelium in children with post-infectious bronchiolitis obliterans is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: High Intensity Intervallic Training in Children With Bronchiolitis Obliterans [NA]
Clinical trial update on high intensity intervallic training for children with bronchiolitis obliterans; the study status is completed.
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Signature of the Host Response to a Respiratory Viral Infection, in the Prediction of Bronchiolitis Obliterans
This study investigates host-response signatures during respiratory viral infections to predict bronchiolitis obliterans in allogeneic hemat…
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Efficacy and Safety of Azithromycin in Patients With Bronchiolitis Obliterans [Phase 4]
A Phase 4 trial assessing the efficacy and safety of azithromycin in patients with bronchiolitis obliterans has completed.
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans [Phase 2]
Phase 2 extension study of cyclosporine inhalation solution in lung and hematopoietic stem cell transplant recipients with bronchiolitis obl…
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CLINICAL_TRIALS trial_result · 2020-04-10Clinical Trial Update: A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHD [Phase 2]
Phase 2 trial evaluating bortezomib for pulmonary chronic GVHD in bronchiolitis obliterans was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: European Trial of Pirfenidone in BOS, A European Multi-center Study [Phase 2, Phase 3]
Phase 2/3 European trial of pirfenidone in Bronchiolitis Obliterans related to lung transplant (CLAD) has completed.
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CLINICAL_TRIALS research · 2018-06-19Clinical Trial Update: Immune Mechanisms of Rejection in Human Lung Allografts
This clinical trial update summarizes research on immune mechanisms of rejection in human lung allografts, with relevance to bronchiolitis o…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Prospective Study for Transplant Optimization Using Functional Imaging (TROFI) [Phase 2]
Phase 2 prospective trial TROFI evaluating transplant optimization using functional imaging; the study sponsored by FLUIDDA nv has been term…
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant Recipients [Phase 1, Phase 2]
Phase 1/2 trial of aerosol liposomal cyclosporine for chronic rejection in lung transplant recipients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-10-04Clinical Trial Update: Targeted Therapy of Bronchiolitis Obliterans Syndrome [Phase 2]
Phase 2 clinical trial update for a targeted therapy in bronchiolitis obliterans; study completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: MSC for Treatment of Interstitial Lung Disease After Allo-HSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating mesenchymal stem cells for interstitial lung disease after allogeneic hematopoietic stem cell trans…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Transplant Optimization Using Functional Imaging [NA]
This is a completed clinical trial sponsored by FLUIDDA nv evaluating transplant optimization using functional imaging. The study addresses …
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Transplant Optimization Using Functional Imaging (TROFI) [NA]
The TROFI trial evaluating transplant optimization using functional imaging has completed, focusing on patients with bronchiolitis obliteran…