Brainstem Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Tumor Treating Fields for the Treatment of Brainstem Gliomas [NA]
An Emory University-sponsored clinical trial is enrolling participants to evaluate Tumor Treating Fields therapy for brainstem gliomas, a su…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling [Phase 1]
Phase 1 clinical trial evaluating ex vivo drug sensitivity testing and multi-omics profiling in pediatric cancers. Recruitment is ongoing ac…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Study on The Sensitizing Effect of Sonodynamic Therapy on The Treatment of Brainstem Glioma With Radiotherapy and Chemotherapy and Survival Analysis [Phase 2]
Phase 2 clinical trial evaluating whether sonodynamic therapy sensitizes brainstem glioma to radiotherapy and chemotherapy, with planned sur…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: MCT for the Harvard/UCSF ROBIN Center [NA]
A clinical trial update showing recruitment is ongoing for an MCT study at the Harvard/UCSF ROBIN Center. The study targets glioma, pediatri…
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CLINICAL_TRIALS research · 2024-08-20Clinical Trial Update: Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
A clinical trial update describing molecular analyses of samples from patients with diffuse intrinsic pontine glioma and brainstem glioma to…
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CLINICAL_TRIALS trial_result · 2021-09-10Clinical Trial Update: First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/or Radiological Infiltrative Pattern of Progression [Phase 2]
Phase 2 trial evaluating first-line temozolomide alone for non-enhancing adult brainstem gliomas with diffuse infiltrative progression patte…
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma [Phase 2]
Phase 2 trial evaluating valproic acid with radiation and bevacizumab in pediatric high-grade gliomas and diffuse intrinsic pontine glioma h…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors [Phase 1]
This Phase 1 trial tests the safety of the p28 peptide in younger patients with recurrent or progressive central nervous system tumors and t…
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CLINICAL_TRIALS withdrawal · 2017-02-20Clinical Trial Update: Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas [EARLY_Phase 1]
Early-phase trial evaluating autologous stem cell collection and reinfusion in newly diagnosed high-grade gliomas has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 [Phase 1]
Phase I trial evaluating intratumoral GRm13Z40-2 T-cell therapy (genetically modified allogeneic CD8+ T cells expressing IL-13-Zetakine and …
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma [Phase 1]
Phase 1 clinical trial investigating an immunotherapy approach for brainstem glioma and glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2014-05-08Clinical Trial Update: ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors [Phase 2]
Completed Phase 2 trial evaluating ANGIOCOMB, an antiangiogenic therapy, in pediatric patients with diffuse brainstem and thalamic tumors.
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CLINICAL_TRIALS trial_result · 2013-12-03Clinical Trial Update: A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas [Phase 2]
A Phase 2 trial evaluating capecitabine with concomitant radiation therapy for newly diagnosed pediatric brainstem gliomas; results were pos…
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment [Phase 2]
Phase 2 trial evaluating oxaliplatin in young patients with recurrent solid tumors that have not responded to prior treatment has completed.…
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: RO4929097 in Treating Patients With Recurrent Invasive Gliomas [Phase 1]
Phase 1 trial update for RO4929097 in recurrent invasive gliomas has been terminated.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction [Phase 1]
Phase 1 clinical trial evaluating erlotinib in patients with solid tumors and liver or kidney dysfunction has been completed.
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CLINICAL_TRIALS trial_result · 2013-01-15Clinical Trial Update: Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma [Phase 2]
Phase 2 trial evaluating bevacizumab combined with irinotecan in pediatric patients with recurrent or progressive brain tumors including gli…
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CLINICAL_TRIALS trial_result · 2012-07-09Clinical Trial Update: Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children [Phase 3]
Phase 3 trial comparing hypofractionated radiotherapy with conventional radiotherapy for diffuse intrinsic pontine glioma in children has co…
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CLINICAL_TRIALS trial_result · 2009-08-07Clinical Trial Update: Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma [Phase 1]
Phase 1 safety study of Tarceva (erlotinib) in children with refractory/relapsed malignant brain tumors and brainstem glioma has completed.