Brain Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) [NA]
This clinical trial update indicates recruitment for a study evaluating omental tissue autograft in patients with recurrent glioblastoma mul…
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CLINICAL_TRIALS withdrawal · 2024-09-03Clinical Trial Update: Multi-modality Localization of Eloquent Brain Function
The clinical trial 'Multi-modality Localization of Eloquent Brain Function' (NCT02795338) has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: FLT-PET Imaging of Brain Tumors in Children [Phase 2]
A Phase 2 trial evaluating FLT-PET imaging for brain tumors in children has completed, and the results have been posted.
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases [EARLY_Phase 1]
This early-phase trial evaluates 18F-FMAU PET/CT with MRI to detect brain tumors in patients with brain cancer or brain metastases. The stud…
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CLINICAL_TRIALS other · 2024-05-06Clinical Trial Update: Register for Longitudinal Recording of Brain Function
A clinical trial at University Hospital Heidelberg is recruiting patients with brain masses or lesions to longitudinally record brain functi…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating the specificity and sensitivity of 5-ALA fluorescence for detecting malignant brain tumors has completed with res…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Molecular Imaging of Brain Tumors Using Labeled Technetium-99m 1-Thio-D-Glucose. [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating molecular imaging of brain tumors using labeled Technetium-99m 1-thio-D-glucose has completed.
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: IORT After Surgical Resection of Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating intraoperative radiotherapy (IORT) after surgical resection of brain metastases is underway.
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CLINICAL_TRIALS trial_result · 2021-12-15Clinical Trial Update: 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients [Phase 4]
Phase 4 trial comparing 1 week versus 6 weeks of levetiracetam in patients with surgical brain tumors; results completed with results posted…
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CLINICAL_TRIALS trial_result · 2021-11-24Clinical Trial Update: A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects [Phase 1, Phase 2]
Phase 1/2 trial update assessing safety, tolerability, and pharmacokinetics of oral dabrafenib in children and adolescents with brain neopla…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain Metastases [Phase 2]
A Phase 2 trial evaluating hippocampal-avoiding whole brain irradiation with a simultaneous integrated boost for brain metastases has comple…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab [Phase 2]
Phase 2 clinical trial evaluating oral pazopanib plus oral topotecan given in a metronomic antiangiogenic regimen for recurrent glioblastoma…
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CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: Hypovitaminosis D in Neurocritical Patients [Phase 2, Phase 3]
Phase 2/3 trial on vitamin D supplementation for neurocritical patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-12Clinical Trial Update: Study of Karenitecin (BNP1350) in Patients With Brain Tumors [Phase 2]
Phase 2 study of Karenitecin (BNP1350) in patients with brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma [Phase 1, Phase 2]
Phase I/II trial comparing bevacizumab alone versus bevacizumab plus TPI-287 for recurrent glioblastoma; trial terminated with results poste…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas [Phase 1, Phase 2]
Phase I/II trial of intramural DTI-015 for recurrent malignant gliomas has been completed.
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FDA approval · 2018-10-16FDA Approved: CARMUSTINE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved the original ANDA for Carmustine (BiCNU) submitted by Amneal Pharmaceuticals LLC.
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FDA approval · 2018-09-11FDA Approved: CARMUSTINE — Original Application (Zydus Pharmaceuticals USA Inc.)
FDA approved Carmustine as an original ANDA for Zydus Pharmaceuticals USA Inc., authorizing a generic Carmustine formulation. The drug is us…
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery [NA]
A completed clinical trial evaluating preoperative Vitamin D supplementation in brain tumor patients reports therapeutic benefit.
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CLINICAL_TRIALS research · 2018-07-10Clinical Trial Update: Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial [Phase 2]
A Phase II clinical trial assesses the combination of bevacizumab and erlotinib in patients with non-small cell lung cancer that has metasta…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma [Phase 1]
This is a terminated Phase 1 open-label study evaluating convection-enhanced delivery of IL-13-PE38QQR in pediatric diffuse infiltrating bra…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Functional Outcomes of The Bobath Approach on Patients With Brain Tumors: Comparison With Stroke Patients
A completed clinical trial evaluates the functional outcomes of the Bobath approach in patients with brain tumors and compares them to strok…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors [Phase 2]
Phase 2 results update on Gefitinib for patients with recurrent or progressive brain and central nervous system tumors. The trial status is …
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Spectrum of Serum Sodium Disturbances in Patients With Non-sellar/Suprasellar Supratentorial Tumors
This clinical trial investigates the spectrum of serum sodium disturbances in patients with non-sellar/suprasellar supratentorial brain tumo…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: A Comparative Study Between Laryngeal Mask Airway and Magensium Sulphate in Attenuating Systemic Stress Response During Emergence of Patients Undergoing Supratentorial Tumours. [NA]
A completed clinical trial comparing use of a laryngeal mask airway versus magnesium sulfate to attenuate systemic stress response during em…