Brain Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-11-24Clinical Trial Update: A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects [Phase 1, Phase 2]
Phase 1/2 trial update assessing safety, tolerability, and pharmacokinetics of oral dabrafenib in children and adolescents with brain neopla…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain Metastases [Phase 2]
A Phase 2 trial evaluating hippocampal-avoiding whole brain irradiation with a simultaneous integrated boost for brain metastases has comple…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab [Phase 2]
Phase 2 clinical trial evaluating oral pazopanib plus oral topotecan given in a metronomic antiangiogenic regimen for recurrent glioblastoma…
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CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: Hypovitaminosis D in Neurocritical Patients [Phase 2, Phase 3]
Phase 2/3 trial on vitamin D supplementation for neurocritical patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-12Clinical Trial Update: Study of Karenitecin (BNP1350) in Patients With Brain Tumors [Phase 2]
Phase 2 study of Karenitecin (BNP1350) in patients with brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma [Phase 1, Phase 2]
Phase I/II trial comparing bevacizumab alone versus bevacizumab plus TPI-287 for recurrent glioblastoma; trial terminated with results poste…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas [Phase 1, Phase 2]
Phase I/II trial of intramural DTI-015 for recurrent malignant gliomas has been completed.
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery [NA]
A completed clinical trial evaluating preoperative Vitamin D supplementation in brain tumor patients reports therapeutic benefit.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma [Phase 1]
This is a terminated Phase 1 open-label study evaluating convection-enhanced delivery of IL-13-PE38QQR in pediatric diffuse infiltrating bra…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Functional Outcomes of The Bobath Approach on Patients With Brain Tumors: Comparison With Stroke Patients
A completed clinical trial evaluates the functional outcomes of the Bobath approach in patients with brain tumors and compares them to strok…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors [Phase 2]
Phase 2 results update on Gefitinib for patients with recurrent or progressive brain and central nervous system tumors. The trial status is …
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Spectrum of Serum Sodium Disturbances in Patients With Non-sellar/Suprasellar Supratentorial Tumors
This clinical trial investigates the spectrum of serum sodium disturbances in patients with non-sellar/suprasellar supratentorial brain tumo…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: A Comparative Study Between Laryngeal Mask Airway and Magensium Sulphate in Attenuating Systemic Stress Response During Emergence of Patients Undergoing Supratentorial Tumours. [NA]
A completed clinical trial comparing use of a laryngeal mask airway versus magnesium sulfate to attenuate systemic stress response during em…
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Quantitative MRI in Assessing Disease in Patients With Brain Tumors [NA]
The trial evaluating quantitative MRI for assessing disease in patients with brain tumors (NCT02269111) has been terminated.
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Improving Surgical Outcomes in Patients With Low Grade Gliomas Using Advanced Pre- and Intra-operative MRI
A completed clinical trial update assessing whether advanced pre- and intra-operative MRI improves surgical outcomes for patients with low-g…
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Perampanel in Seizure Patients With Primary Glial Brain Tumors [Phase 4]
Phase 4 study of perampanel for seizures in patients with primary glial brain tumors completed; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases [Phase 1]
Phase I clinical trial evaluating ABT-888 (veliparib) in combination with whole-brain radiation therapy for patients with brain metastases h…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Fluid Therapy During Brain Tumor Resection in Children [Phase 2]
A Phase 2 trial evaluating fluid therapy during pediatric brain tumor resection has completed.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy [Phase 1]
Phase 1 clinical trial evaluating metabolic manipulation in combination with radiotherapy for recurrent brain tumors, sponsored by Sheba Med…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS [EARLY_Phase 1]
An early-phase clinical trial update evaluating ferumoxytol-enhanced MRI to measure inflammation in patients with brain tumors and other CNS…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial [Phase 1]
Phase I dose-escalation study evaluating the safety and feasibility of combining fractionated stereotactic radiosurgery with bevacizumab for…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: 18F-FET PET in Childhood Brain Tumours [Phase 2]
Phase 2 clinical trial evaluating 18F-FET PET imaging in childhood brain tumors.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Gene Therapy for the Treatment of Brain Tumors [Phase 1]
Phase 1 gene therapy trial for brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Hyperbaric Oxygen Stimulation for Patients With Brain Malignancies After Radiation Therapy. [NA]
The clinical trial evaluating hyperbaric oxygen stimulation for brain malignancies after radiation therapy was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143) [Phase 2]
Phase 2 study P02143 evaluating temozolomide for brain metastases from non-small-cell lung cancer has been terminated. The sponsor is Merck …