Brain Metastasis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Mind-Body Intervention in Glioma Couples [NA]
Clinical trial update for a mind-body intervention targeting glioma patients and their partners. The study is currently active but not recru…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Stereotactic Radiotherapy in Oligometastatic Brain Disease: a Randomised Phase III Study Comparing Hypofractionated Stereotactic Radiation Therapy (3*10 Gy) to the Historical Single-dose Radiosurgery (1*20 to 25 Gy) With Medico-economic Evaluation. [NA]
Clinical trial update for a Phase III randomized study comparing hypofractionated stereotactic radiotherapy (3x10 Gy) to historical single-d…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Evaluation of Neoadjuvant Stereotactic Radiosurgery (SRS) and Multi-fraction SRS Alone for the Treatment of Large Brain Metastases [Phase 3]
Phase 3 trial evaluating neoadjuvant stereotactic radiosurgery and multi-fraction SRS for large brain metastases; status not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis [Phase 2]
Phase 2 clinical trial investigating MRI-guided adaptive stereotactic radiotherapy to eliminate planning target volume margins in non-small …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Evaluating Biomarkers of Cognitive Dysfunction in Patients With Cancer
A clinical trial update on evaluating biomarkers of cognitive dysfunction in cancer patients, with status NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Phase I/II Study of Intrathecal/Ommaya T-DXd in HER2-Expressing Breast Cancer With Leptomeningeal/Brain Metastases [Phase 1, Phase 2]
Phase I/II study investigating intrathecal administration of trastuzumab deruxtecan (T-DXd) via Ommaya for HER2-expressing breast cancer wit…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors [Phase 1]
Phase 1 study evaluating panobinostat with stereotactic radiation therapy for brain tumors, including recurrent glioma, high-grade meningiom…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
Completed results from a clinical trial evaluating robotic laser ablation with the NeuroBlate system for treating brain tumors and epileptic…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor [NA]
This entry describes a clinical trial evaluating intraoperative radiation therapy for malignant brain tumors, including glioblastoma, which …
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery [Phase 1, Phase 2]
Clinical trial comparing T-DM1 alone versus T-DM1 with metronomic temozolomide in HER2-positive breast cancer brain metastases after stereot…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Evaluation of the Use of Trental and Vitamin E For Prophylaxis of Radiation Necrosis [Phase 2]
Phase 2 clinical trial evaluating Trental (pentoxifylline) and vitamin E for prophylaxis of radiation necrosis in brain metastasis patients;…
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CLINICAL_TRIALS trial_result · 2021-12-30Clinical Trial Update: Seizure Prophylaxis in Patients With Glioma or Brain Metastasis [Phase 2]
Phase 2 trial update on seizure prophylaxis in patients with glioma or brain metastasis; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-04-13Clinical Trial Update: Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer [Phase 2]
Phase 2 trial evaluating whole-brain radiation therapy or stereotactic radiosurgery with or without lapatinib for brain metastases from HER2…
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer [Phase 4]
A single-arm Phase 4 clinical trial assessing brain metastasis in patients with HER2-positive breast cancer.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial update for patupilone in patients with brain metastasis from non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-Brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer [Phase 3]
Phase 3 trial evaluating whether hippocampal avoidance during whole-brain radiation reduces cognitive toxicity after surgical resection of a…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors [Phase 1]
Phase 1 feasibility and dose-escalation study using intracerebral microdialysis to assess the neuropharmacodynamics of temsirolimus in patie…
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CLINICAL_TRIALS withdrawal · 2017-08-10Clinical Trial Update: NovoTTF-100A Therapy for Refractory CNS Involved Small Cell Lung Cancer [Phase 2]
The Phase 2 trial of NovoTTF-100A Therapy for refractory CNS-involved small cell lung cancer (including brain metastases) has been withdrawn…
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CLINICAL_TRIALS withdrawal · 2014-02-04Clinical Trial Update: Exclusive Hypofractionated Stereotactic Radiotherapy in Non-resectable Single Brain Metastasis [Phase 2]
A Phase 2 study of exclusive hypofractionated stereotactic radiotherapy for a non-resectable single brain metastasis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis [Phase 2]
Phase 2 trial of Vorinostat with concurrent whole brain radiotherapy for brain metastasis was terminated.
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CLINICAL_TRIALS trial_result · 2011-09-27Clinical Trial Update: Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating temozolomide with radiation therapy for brain metastases from non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2010-09-06Clinical Trial Update: A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases [Phase 3]
A Phase 3 trial comparing radiosurgery with surgical resection for solitary brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2009-07-28Clinical Trial Update: Pemetrexed Plus Cisplatin for Brain Metastasis of Advanced Non - Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 study evaluating pemetrexed plus cisplatin for brain metastases in advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2008-02-22Clinical Trial Update: Efficacy of Gefitinib for Brain Metastasis of Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating Gefitinib for brain metastases in non-small cell lung cancer; the update notes the trial status as UN…