Botulism
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CLINICAL_TRIALS trial_result · 2026-06-18Clinical Trial Results: Tolerability and Immunogenicity of a Single 40-ug Dose of rBV A/B for the Production of BabyBIG® [Phase 2]
Phase 2 trial assessing tolerability and immunogenicity of a single 40-µg dose of rBV A/B for BabyBIG production in botulism.
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric Patients [Phase 4]
An update on a Phase 4 pharmacokinetic study of botulism antitoxin heptavalent (BT-011) in pediatric patients, currently enrolling by invita…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Pilot Study on the Usefulness of 3,4-diaminopyridine in the Treatment of Botulism [Phase 2, Phase 3]
The document reports the completion of a Phase 2/Phase 3 pilot clinical trial evaluating 3,4-diaminopyridine for botulism.
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Tolerability and Immunogenicity of a Single 40-ug Dose of rBV A/B for the Production of BabyBIG® [Phase 2]
Phase 2 trial update reports tolerability and immunogenicity of a single 40-µg dose of rBV A/B used in the production of BabyBIG.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Effect of Amifampridine on Neuromuscular Transmission in Patients Treated With OnabotulinumtoxinA [Phase 1]
Phase 1 study evaluating the effect of amifampridine on neuromuscular transmission in patients treated with onabotulinumtoxinA. The trial st…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Study of the Drug B11-FC (Botulism Treatment) [Phase 1, Phase 2]
This clinical trial update notes that B11-FC is being studied as a botulism treatment in Phase 1/Phase 2 and has not yet recruited.
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CLINICAL_TRIALS trial_result · 2021-10-19Clinical Trial Update: Tolerability and Immunogenicity of rBV A/B for the Production of BabyBIG® [Phase 2]
Phase 2 trial evaluating tolerability and immunogenicity of rBV A/B for producing BabyBIG® has completed with results posted.
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CLINICAL_TRIALS withdrawal · 2018-12-04Clinical Trial Update: Phase 3, Randomized, Safety, Lot Consistency and Clinical Benefit Study of Recombinant Botulinum Vaccine A/B [Phase 3]
Phase 3 trial investigating a recombinant botulinum vaccine (A/B) for botulism was withdrawn.
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Safety, Tolerability, and Immunogenicity Study of Investigational Recombinant Botulinum Vaccine A/B (rBV A/B) in Volunteers Previously Immunized With Investigational Pentavalent Botulinum Toxoid [Phase 2]
A Phase 2 safety, tolerability, and immunogenicity study of an investigational recombinant botulinum vaccine A/B in volunteers previously im…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Study of Human Botulism Immunoglobulin in Infants With Botulism [NA]
The clinical trial evaluating Human Botulism Immunoglobulin in infants with botulism has completed.
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Phase 1 PK Study of XOMA 3AB [Phase 1]
A Phase 1 pharmacokinetic study of XOMA 3AB for botulism sponsored by NIAID has been completed.
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: Study to Evaluate the Safety, Tolerability and Immunogenicity of Recombinant Botulinum Vaccine A/B in Healthy Adults [Phase 1]
A Phase 1 trial evaluated the safety, tolerability, and immunogenicity of Recombinant Botulinum Vaccine A/B in healthy adults and has comple…
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CLINICAL_TRIALS trial_result · 2011-12-02Clinical Trial Update: Double Blind, Safety and Immunogenicity Study of Recombinant Botulinum Vaccine A/B [Phase 2]
This clinical trial update reports completion of a Phase 2, double-blind safety and immunogenicity study of Recombinant Botulinum Vaccine A/…
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CLINICAL_TRIALS trial_result · 2008-10-24Clinical Trial Update: Treatment of Survivors After Botulism Outbreak
A completed clinical trial update examining treatments for survivors of a botulism outbreak, including patients with respiratory failure.
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CLINICAL_TRIALS trial_result · 2006-11-08Clinical Trial Update: Botulism Outbreak in Thailand (Episode II)
This is a completed clinical trial update on the botulism outbreak in Thailand (Episode II). The sponsor is the Department of Medical Servic…