Bone Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-11-14Clinical Trial Update: ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain [NA]
A completed clinical trial evaluating ExAblate MR-guided focused ultrasound for palliation of pain in bone metastases and multiple myeloma; …
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Standard Dose Versus High Dose and Versus Extended Standard Dose Radium-223 Dichloride in Castration-resistant Prostate Cancer Metastatic to the Bone [Phase 2]
Phase 2 trial comparing standard dose, high dose, and extended standard dose of Radium-223 dichloride in metastatic castration-resistant pro…
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FDA approval · 2018-06-29FDA Approved: ZOLEDRONIC ACID — Original Application (Gland Pharma Limited)
The FDA approved an Original Application for a generic zoledronic acid product by Gland Pharma Limited.
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CLINICAL_TRIALS trial_result · 2018-06-08Clinical Trial Update: Safety, Tolerability and PK/PD of JMT103 in Patients With Bone Metastases From Tumors [Phase 1]
Phase 1 clinical trial update assessing safety, tolerability and PK/PD of JMT103 in patients with bone metastases from tumors.
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: MR Guided Focused Ultrasound Surgery in the Treatment of Pain From Bone Tumors w/ the ExAblate 2000 Strappable System [NA]
Clinical trial evaluating MR-guided focused ultrasound surgery with the ExAblate 2000 Strappable System for pain management in bone metastas…
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CLINICAL_TRIALS research · 2018-06-04Clinical Trial Update: A Pilot Study to Enhance F18 FDG-PET Imaging of Prostate Cancers With the Metabolic Inhibitor Ranolazine [NA]
Pilot study evaluating whether the metabolic inhibitor ranolazine can enhance F18 FDG-PET imaging of prostate cancer.
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CLINICAL_TRIALS research · 2018-04-20Clinical Trial Update: Short Course Radiation Therapy in Palliative Treatment of Complicated Bone Metastases [NA]
This is a clinical trial update describing a short course of radiation therapy for palliative treatment of complicated bone metastases; the …
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: First-In Man (FIM) Study MR-Linac [NA]
The document reports a completed first-in-man study of the MR-Linac radiotherapy device for treating bone metastases.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Short Course Radiotherapy in Complicated Bone Metastases Palliation [NA]
A completed clinical trial evaluating short-course radiotherapy for palliation in patients with complicated bone metastases.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma [Phase 3]
Phase 3 trial comparing denosumab with zoledronic acid for bone disease in multiple myeloma completed; results posted in 2018.
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CLINICAL_TRIALS research · 2018-03-05Clinical Trial Update: Evaluation of the Ability of CT-based Finite Element Analysis (CTFEA) to Predict Fractures in Patients With Metastases: a Randomized Controlled Study. [NA]
This clinical trial update describes a randomized controlled study evaluating whether CT-based finite element analysis (CTFEA) can predict f…
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CLINICAL_TRIALS trial_result · 2017-12-13Clinical Trial Update: Cryosurgery and Radiation Therapy in Treating Patients With Painful Bone Metastases [NA]
A terminated clinical trial evaluating cryosurgery plus radiation therapy for painful bone metastases; results posted in 2017.
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CLINICAL_TRIALS research · 2017-11-27Clinical Trial Update: Double-bed SPECT/CT for Bone Scintigraphy in Initial Staging of Cancer Patients
Clinical trial update on using double-bed SPECT/CT imaging for bone scintigraphy in the initial staging of cancer patients with bone metasta…
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: Hypofractionated Radiotherapy (16/2) for the Palliation of Complicated Bone Metastases in Patients With KPS [Phase 2]
Phase 2 trial results evaluating a hypofractionated radiotherapy regimen (16 fractions of 2 Gy) for palliation of complicated bone metastase…
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CLINICAL_TRIALS trial_result · 2017-09-15Clinical Trial Update: Correlation of MR Thermal Imaging to Actual Size of Ablation During Laser Ablation Therapy [Phase 4]
Phase 4 clinical trial assessing correlation between MR thermal imaging and actual ablation size during laser ablation therapy in advanced c…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: MR-HIFU for Bone Metastases [NA]
A completed clinical trial evaluated MRI-guided high-intensity focused ultrasound (MR-HIFU) for bone metastases; the study status is COMPLET…
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CLINICAL_TRIALS withdrawal · 2017-08-16Clinical Trial Update: A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease. [Phase 2]
Phase 2 trial of intravenous ibandronate (Bondronat) in breast cancer patients with metastatic bone disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: A Study to Determine the Safety, Tolerability, Pharmacokinetics and Dynamic Effects of Different Doses of the Study Drug EMD 525797 in Prostate Cancer [Phase 1]
A completed Phase 1 study evaluated safety, tolerability, pharmacokinetics, and dynamic effects of different doses of EMD 525797 in prostate…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: NaF Positron Emission Tomography/Computed Tomography (PET/CT)Imaging to Assess Treatment Responsiveness to TAK-700 in Patients With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastasis [Phase 2]
Phase 2 trial update investigating NaF PET/CT imaging to assess treatment response to TAK-700 in castration-resistant prostate cancer with b…
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CLINICAL_TRIALS trial_result · 2017-06-02Clinical Trial Update: Efficacy and Safety of Zoledronic Acid in the Treatment of Bone Metastases-related Pain in Patients With Prostate Cancer [Phase 3]
Phase 3 trial evaluating the efficacy and safety of zoledronic acid for bone metastases-related pain in patients with prostate cancer.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions [Phase 4]
Phase 4 trial evaluating the efficacy and tolerability of zoledronic acid combined with radiotherapy in patients with advanced osteolytic bo…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With Metastatic Hormone-Resistant Prostate Cancer [Phase 1]
A Phase 1 trial assessing imaging-based response to Radium-223 dichloride in metastatic, hormone-resistant prostate cancer; the study has be…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Dose Escalation Study of Radium-223 Dichloride in Patients With Advanced Skeletal Metastases [Phase 1]
A Phase 1 dose-escalation study of Radium-223 dichloride in patients with advanced skeletal metastases has completed.
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: S0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone Metastases That Did Not Respond to Previous Hormone Therapy [Phase 3]
Phase 3 trial of docetaxel and prednisone with or without atrasentan in metastatic prostate cancer with bone metastases after hormone therap…
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CLINICAL_TRIALS other · 2017-04-12Clinical Trial Update: The STAR™ Tumor Ablation Registry
A clinical trial registry update notes that Merit Medical's STAR Tumor Ablation Registry (NCT02419703) has been terminated.