Bone Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-12-01Clinical Trial Update: Rapid Radiation Therapy for Painful Osseous Metastatic Disease [NA]
A completed clinical trial investigating rapid radiation therapy for painful osseous metastatic disease (bone metastases) with results poste…
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: Diagnostic Performance and Safety of 18F-NaF-PET/CT in Bone Metastases Compared With 99mTc⁃MDP-BS±SPECT [Phase 3]
Phase 3 clinical trial comparing 18F-NaF-PET/CT to 99mTc-MDP-BS±SPECT for diagnostic performance and safety in bone metastases; study comple…
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CLINICAL_TRIALS trial_result · 2022-10-13Clinical Trial Update: Telemonitoring After Surgery to Preserve Limb Function in Optimizing Mobility in Cancer Survivors With Skeletal Metastases [NA]
Clinical trial on telemonitoring after surgery to preserve limb function in cancer survivors with skeletal metastases has been terminated; r…
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: Efficacy of Sr-89 for Differentiated Thyroid Cancer With Bone Metastases [Phase 4]
Phase 4 trial update on the efficacy of Strontium-89 (Sr-89) for differentiated thyroid cancer with bone metastases.
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FDA approval · 2022-04-05FDA Approved: ZOLEDRONIC ACID — Supplemental Application (Sagent Pharmaceuticals)
The FDA approved a supplemental application for Zoledronic acid submitted by Sagent Pharmaceuticals, updating regulatory labeling per the su…
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CLINICAL_TRIALS trial_result · 2022-02-25Clinical Trial Update: Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis [Phase 1, Phase 2]
Phase 1/2 trial investigating dasatinib combined with zoledronic acid for breast cancer with bone metastases; study completed with results p…
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CLINICAL_TRIALS trial_result · 2021-11-08Clinical Trial Update: A Randomized Trial Evaluating Rapid Delivery of Dose Escalated Hypofractionated Radiotherapy for Patients Diagnosed With Bone Metastases for Effective Palliation of Symptoms [Phase 2, Phase 3]
A randomized study evaluating rapid delivery of dose-escalated hypofractionated radiotherapy for palliation in patients with bone metastases…
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: The Combination Therapy With Ra-223 and Enzalutamide [Phase 2]
Phase 2 trial update on combining Ra-223 with Enzalutamide for castration-resistant prostate cancer with bone metastases.
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer [Phase 2]
A Phase 2 clinical trial evaluating morphine analgesia after radiofrequency ablation of painful bone metastases in cancer patients; the stud…
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Open Label Extension In Cancer Patients [Phase 2]
Open-label extension study in cancer patients (Phase 2) completed; results posted in 2021.
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EMA approval · 2020-11-20EMA Authorised: Zoledronic acid medac (zoledronic acid monohydrate) — medac Gesellschaft für klinische Spezialpräparate mbH
The EMA authorised zoledronic acid monohydrate (Zoledronic acid medac) for use in fractures/bone-related conditions and cancer, under the ma…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Dexamethasone vs Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy for Bone Metastases [Phase 3]
Phase 3 trial assessing dexamethasone versus placebo to prevent radiation-induced pain flare after palliative radiotherapy for bone metastas…
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FDA approval · 2020-10-20FDA Approved: ZOLEDRONIC ACID — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for Zoledronic acid from Hikma Pharmaceuticals USA Inc., indicating regulatory approval for the spon…
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FDA approval · 2020-10-19FDA Approved: ZOLEDRONIC ACID — Supplemental Application (Mylan Institutional LLC)
FDA approved a supplemental application for zoledronic acid from Mylan Institutional LLC under an abbreviated new drug application (ANDA), e…
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CLINICAL_TRIALS trial_result · 2020-09-22Clinical Trial Update: To Evaluate the Efficacy and Safety of QL1206 and Xgeva in Patients With Bone Metastases From Solid Tumors [Phase 3]
Phase 3 trial evaluating QL1206 and Xgeva for bone metastases from solid tumors.
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer [Phase 2]
Phase 2 trial evaluating MRI as a measurement tool for the effect of cabozantinib in patients with castration-resistant prostate cancer.
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain [NA]
Clinical trial update for ExAblate Conformal Bone System in metastatic bone tumors shows terminated status with posted results.
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FDA approval · 2020-02-21FDA Approved: ZOLEDRONIC ACID — Supplemental Application (Dr. Reddy's Laboratories Limited)
The FDA approved a supplemental application for Zoledronic acid from Dr. Reddy's Laboratories Limited, authorizing a generic product through…
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FDA approval · 2020-02-21FDA Approved: ZOLEDRONIC ACID — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for zoledronic acid submitted by BluePoint Laboratories (ANDA205279).
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases [Phase 2]
A phase 2 randomized trial compares high-dose vs standard-dose stereotactic radiotherapy for pain control in patients with bone metastases.
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Lazanda in Cancer Patients Receiving Palliative Radiation [Phase 2]
Phase 2 clinical trial update for Lazanda used in cancer patients receiving palliative radiation, terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-07-09Clinical Trial Update: Androgen Deprivation Therapy +/- Radium-223 Dichloride in Metastatic Prostate Cancer With Bone Metastases [Phase 2]
Phase 2 trial evaluating androgen deprivation therapy with or without Radium-223 dichloride in metastatic prostate cancer with bone metastas…
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: 18F-NaF PET Imaging for Bone Scintigraphy [Phase 3]
Phase 3 trial update on 18F-NaF PET imaging for bone scintigraphy in patients with bone metastases from breast or prostate cancer.
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer
A clinical trial evaluating dual-energy CT to detect bone metastases in cancer patients has been terminated.
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cells [Phase 2]
Phase 2 clinical trial evaluating denosumab for ER+/PR+ and/or HER2-negative metastatic breast cancer with bone metastases and detectable ci…