Bipolar Disorder
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
The AMBiGen trial, sponsored by the National Institute of Mental Health, completed an investigation into how the COVID-19 pandemic affected …
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: 'Thriving With Bipolar Disorder': Co-design and Evaluation of a Peer-Led Education Program Focused on Quality of Life [NA]
A clinical trial update describes a co-designed, peer-led education program for individuals with bipolar disorder, focused on improving qual…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Mechanisms of Transcutaneous Auricular Vagus Nerve Stimulation in Depression [NA]
A clinical trial investigates the mechanisms of transcutaneous auricular vagus nerve stimulation for depressive disorders and is currently r…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Investigation of Factors Associated With Preserved Cognitive Function in Bipolar Disorder
Clinical trial investigating factors linked to preserved cognitive function in individuals with bipolar disorder; currently active but not r…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness [NA]
This clinical trial update notes that enrollment is ongoing by invitation for a study evaluating a mobile health post-discharge intervention…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: App and Body Fat Scale in the Management of Overweight Patients [NA]
Trial status update for a study evaluating an app and body fat scale to manage overweight in patients with schizophrenia or bipolar disorder…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Mindfulness Psychoeducation for Bipolar Disorder Caregivers' Mindfulness, Burden, Quality of Life and Resilience [NA]
A clinical trial evaluating a mindfulness psychoeducation program for caregivers of individuals with bipolar disorder. The study will assess…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
This clinical trial update describes a study led by Douglas Mental Health University Institute examining behavioural development, long-term …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder [EARLY_Phase 1]
A Phase 1 clinical trial is recruiting to evaluate xenon inhalation therapy for major depressive disorder and bipolar disorder.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression [Phase 4]
A Phase 4 pilot study evaluating the efficacy of minocycline and N-acetylcysteine for bipolar depression has been suspended.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling [NA]
A Stanford University-sponsored trial investigates ketogenic metabolic therapy (ketogenic dieting) for schizophrenia, bipolar disorder, and …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Skills for Wellness [NA]
This is a clinical trial update for the Skills for Wellness study. It is currently recruiting participants with schizophrenia, bipolar disor…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
Clinical trial update announcing the CDRIN Maritimes Registry, a prospective registry for depression and trauma-related disorders, currently…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use [NA]
A clinical trial evaluating whether genetic counselling can prevent mental health problems associated with cannabis use; the study is curren…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Analysis of Early Neurodevelopmental Alterations in Bipolar Disorder Based on Cortical Organoid Models [NA]
An update on a clinical trial evaluating early neurodevelopmental alterations in bipolar disorder using cortical organoid models. The study …
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium [Phase 4]
Phase 4 clinical trial evaluating amiloride for nephrogenic diabetes insipidus in patients with bipolar disorder treated with lithium; trial…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Dallas 2K: A Natural History Study of Depression
Dallas 2K is a natural history study of depression sponsored by the University of Texas Southwestern Medical Center, currently recruiting.
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Cannabidiol for Bipolar Depression (CBD-BD) [Phase 3]
A Phase 3 clinical trial investigating cannabidiol (CBD) for bipolar depression is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder [NA]
A clinical trial is investigating intermittent theta burst stimulation (iTBS) as a way to improve emotion regulation in individuals with bip…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Open Label Extension Study of NCT06221852 [NA]
Open-label extension study NCT06221852 is currently enrolling by invitation. The sponsor is McLean Hospital and the study targets Bipolar I …
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Behavioural Activation for Bipolar Depression [NA]
A clinical trial at Reykjavik University is recruiting to evaluate behavioural activation as a treatment for bipolar depression.
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
An ongoing Mayo Clinic study recruiting participants to identify cerebral hemodynamic patterns in mood disorders and mild cognitive impairme…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Apathy-related Neurobehavioral Markers of Cognitive Decline in Old-age Bipolar Disorders: Proof-of-concept
A proof-of-concept clinical study exploring apathy-related neurobehavioral markers of cognitive decline in elderly individuals with bipolar …
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder [NA]
This clinical trial update indicates that a study assessing Acceptance and Commitment Therapy for depressive symptoms in Bipolar Disorder is…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Metacognitive Training With Bipolar Disorder Patients. [NA]
This document provides an update on a clinical trial evaluating metacognitive training for patients with bipolar disorder. The study is curr…