Biliary Tract Carcinoma

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer [Phase 2]

  A Phase 2 trial sponsored by Mayo Clinic compares at-home cancer-directed therapy to in-clinic treatment for patients with various advanced …

• CLINICAL_TRIALS research · 2026-01-21
  Clinical Trial Update: Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer [Phase 2]

  A Phase 2 clinical trial is evaluating olanzapine for cancer-associated appetite loss in patients with advanced esophageal, gastric, colorec…

• CLINICAL_TRIALS research · 2026-01-14
  Clinical Trial Update: GEMOX Combined With Donafenib and Tislelizumab in Advanced Biliary Tract Carcinoma [Phase 2]

  A Phase 2 clinical trial update evaluating GEMOX (gemcitabine + oxaliplatin) in combination with donafenib and tislelizumab for advanced bil…

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer [Phase 2]

  A Phase 2 trial evaluating different dosing schedules of selumetinib in combination with cisplatin and gemcitabine versus cisplatin/gemcitab…

• CLINICAL_TRIALS research · 2025-08-01
  Clinical Trial Update: Study of ZG005 in Combination With Platinum-Based Chemotherapy in Participants With Advanced Biliary Tract Carcinoma [Phase 2]

  A Phase 2 clinical trial evaluating ZG005 in combination with platinum-based chemotherapy for advanced biliary tract carcinoma, with the stu…

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• CLINICAL_TRIALS trial_result · 2024-10-15
  Clinical Trial Update: SBRT Sequential Surufatinib Combined With Immunotherapy for Biliary Tract Carcinoma [Phase 2]

  A Phase 2 trial examining SBRT followed by surufatinib with immunotherapy for biliary tract carcinoma is currently suspended.

• CLINICAL_TRIALS research · 2024-08-27
  Clinical Trial Update: A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies. [NA]

  A multicenter Phase II basket trial at Zhejiang Cancer Hospital is evaluating hypofractionated radiotherapy or SBRT followed by immunotherap…

• CLINICAL_TRIALS research · 2024-05-28
  Clinical Trial Update: Clinical Study of Irinotecan Hydrochloride Liposome Combined With Capecitabine for Second-line Treatment in Patients With Advanced or Metastatic Biliary Tract Carcinoma [Phase 2]

  This is a Phase 2 clinical trial evaluating irinotecan hydrochloride liposome in combination with capecitabine as second-line therapy for ad…

• CLINICAL_TRIALS trial_result · 2024-05-17
  Clinical Trial Update: Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer [Phase 1, Phase 2]

  A Phase 1/2 clinical trial update reports results for a combination of liposomal irinotecan, fluorouracil, leucovorin, and rucaparib in pati…

• CLINICAL_TRIALS trial_result · 2023-12-26
  Clinical Trial Update: Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966)-China Extension Study [Phase 3]

  Phase 3 China extension study comparing pembrolizumab plus gemcitabine/cisplatin against placebo plus gemcitabine/cisplatin as first-line tr…

• CLINICAL_TRIALS trial_result · 2023-10-13
  Clinical Trial Update: Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations [Phase 2]

  Phase 2 trial investigating olaparib for metastatic biliary tract cancer with aberrant DNA repair gene mutations.

• CLINICAL_TRIALS trial_result · 2023-08-15
  Clinical Trial Update: GP Chemotherapy in Combination With Anti-PD-1 and Anti-TIGIT in Unresectable Advanced BTC [Phase 2]

  A Phase 2 trial evaluating GP chemotherapy in combination with anti-PD-1 and anti-TIGIT in unresectable advanced biliary tract carcinoma is …

• CLINICAL_TRIALS trial_result · 2021-08-09
  Clinical Trial Update: GEMOX Combined With Donafenib and Tislelizumab in Biliary Tract Cancer [Phase 1, Phase 2]

  Clinical trial of GEMOX with donafenib and tislelizumab in biliary tract carcinoma is in Phase 1/2 with unknown results to date.

• CLINICAL_TRIALS trial_result · 2020-11-17
  Clinical Trial Update: First Line Gemcitabine, Cisplatin and MEK162 in Advanced Biliary Tract Carcinoma [Phase 1, Phase 2]

  A Phase 1/2 trial evaluating first-line gemcitabine, cisplatin, and MEK162 in advanced biliary tract carcinoma has completed with results po…