Biliary Atresia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-07Clinical Trial Results: Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating obeticholic acid versus placebo in pediatric biliary atresia post-hepatoportoenterostomy; study terminat…
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Update: Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD) [Phase 3]
Phase 3 trial update on the efficacy and safety of odevixibat in children with biliary atresia post-Kasai procedure (BOLD study).
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Kasai Portoenterostomy Timing and Outcomes in Biliary Atresia
A clinical trial evaluating the timing and outcomes of Kasai portoenterostomy in biliary atresia has completed.
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy [Phase 2, Phase 3]
A terminated Phase 2/3 clinical trial evaluating obeticholic acid versus placebo in pediatric biliary atresia patients after hepatoportoente…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia [Phase 1]
Phase 1 clinical trial evaluating the safety and outcomes of adding Umbilical Cord Mesenchymal Stem Cells to early Kasai portoenterostomy in…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai [Phase 2]
Phase 2 trial evaluating maralixibat in biliary atresia patients after Kasai procedure has completed; results were posted on 2025-02-17.
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
This update reports on the FORCE trial evaluating FibroScan, a non-invasive liver fibrosis assessment tool, in pediatric cholestatic liver d…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy [Phase 3]
A Phase 3 clinical trial evaluated norepinephrine to prevent intraoperative hypotension in infants undergoing Kasai portoenterostomy for bil…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation for Children Suffering From Biliary Atresia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating umbilical cord–derived mesenchymal stem cell transplantation in children with biliary atresia; the study…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia [Phase 2]
Phase 2 trial evaluating autologous bone marrow mononuclear cells for children with biliary atresia–related liver cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy [Phase 2]
Phase 2 clinical trial update evaluating N-acetylcysteine after Kasai Portoenterostomy for biliary atresia has completed with results posted…
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Pentoxifylline Therapy in Biliary Atresia [Phase 2]
Phase 2 clinical trial update for pentoxifylline therapy in biliary atresia; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-08Clinical Trial Update: Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia [Phase 2]
Phase 2 clinical trial exploring granulocyte-colony stimulating factor adjunct therapy for biliary atresia.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Safety Study of Intravenous Immunoglobulin (IVIG) Post-Portoenterostomy in Infants With Biliary Atresia [Phase 1, Phase 2]
Phase 1/2 trial evaluating the safety of intravenous immunoglobulin (IVIG) after portoenterostomy in infants with biliary atresia has comple…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy [NA]
A randomized, double-blinded, placebo-controlled trial evaluating corticosteroid therapy after portoenterostomy for biliary atresia has comp…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: the Correlation Between Non-invasive Indicators in Patients With Biliary Atresia
Clinical trial update reporting the relationship between non-invasive indicators and hepatic fibrosis status in patients with biliary atresi…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin [Phase 1]
Phase 1 study assessing the effects of vancomycin on gastrointestinal microbiota in patients with Primary Sclerosing Cholangitis and Biliary…
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Biliary Atresia, Hepatic Buffer Response and Sevoflurane
A completed clinical trial conducted at the Children's Hospital of Fudan University investigated biliary atresia and the hepatic buffer resp…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: Clinical Study About the Role of COX-2 Inhibitor in Liver Cirrhosis With Biliary Atresia [Phase 4]
A Phase 4 clinical trial evaluating a COX-2 inhibitor in biliary atresia with liver cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2014-07-22Clinical Trial Update: The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai Operation [NA]
This clinical trial update compares desflurane and sevoflurane for postoperative recovery and hepatic function in biliary atresia patients u…
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CLINICAL_TRIALS trial_result · 2013-08-21Clinical Trial Update: Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy [NA]
This clinical trial update reports on the use of probiotics to prevent cholangitis in children with biliary atresia after Kasai portoenteros…
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CLINICAL_TRIALS trial_result · 2010-02-05Clinical Trial Update: Survival With Own Liver of Conventional Versus Laparoscopic Kasai for Biliary Atresia [NA]
A completed clinical trial comparing conventional versus laparoscopic Kasai procedures for biliary atresia and its effect on survival with t…
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CLINICAL_TRIALS trial_result · 2009-01-22Clinical Trial Update: Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease [NA]
A completed clinical trial evaluating magnesium sulfate in children with reduced bone density due to chronic cholestatic liver disease, incl…
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CLINICAL_TRIALS trial_result · 2007-10-04Clinical Trial Update: RCT of Steroids Following Kasai Portoenterostomy for Biliary Atresia. [Phase 3]
A Phase 3 randomized trial is evaluating corticosteroid therapy after Kasai portoenterostomy for biliary atresia; the current status is unkn…