Beta-thalassemia
📧 Sign up to get email alerts when something new happens for Beta-thalassemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia [Phase 3]
Phase 3 trial comparing luspatercept to placebo in adults with beta-thalassemia requiring regular red blood cell transfusions; results poste…
-
FDA approval · 2019-11-20FDA Approved: DEFERASIROX — Original Application (Alembic Pharmaceuticals Limited)
FDA approved the Original Application for Deferasirox from Alembic Pharmaceuticals Limited (ANDA211824).
-
FDA approval · 2019-11-08FDA Approved: REBLOZYL — Original Application (Celgene Corporation)
The FDA approved the original application for Reblozyl (luspatercept) from Celgene. This adds a new biologic for adults with transfusion-dep…
-
CLINICAL_TRIALS trial_result · 2019-10-23Clinical Trial Update: Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload [Phase 2]
Phase 2 trial assessing safety and efficacy of deferasirox combined with desferoxamine in transfusion-dependent beta-thalassemia patients wi…
-
CLINICAL_TRIALS trial_result · 2019-06-28Clinical Trial Update: Gene Therapy for Transfusion Dependent Beta-thalassemia [Phase 1, Phase 2]
Phase 1/2 clinical trial update for a gene therapy targeting transfusion-dependent beta-thalassemia.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2019-05-23Clinical Trial Update: Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C Virus [Phase 4]
Phase 4 clinical trial evaluating hyalurnic acid levels in β-thalassemic children treated for hepatitis C.
-
CLINICAL_TRIALS research · 2019-01-30Clinical Trial Update: Detection Of β-thalassemia Carriers In Assiut [NA]
This clinical trial update from Assiut University concerns detection of beta-thalassemia carriers in Assiut. The status is unknown and no tr…
-
CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: the Efficacy and Safety of Sugammadex in Children 0-2 Years Old [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating the efficacy and safety of sugammadex in children aged 0-2 years for anesthesia-related use, wit…
-
CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: A Study of Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-Thalassemia [Phase 2]
Phase 2 trial update of Bitopertin (RO4917838) in adults with non-transfusion-dependent beta-thalassemia has completed.
-
CLINICAL_TRIALS trial_result · 2018-08-27Clinical Trial Update: L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension [Phase 4]
Phase 4 trial comparing L-arginine to sildenafil in children with beta thalassemia and pulmonary hypertension.
-
CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant [Phase 2]
Phase 2 clinical trial update on CD34+ selection for partially matched family or matched unrelated adult donor transplants in leukemia and l…
-
CLINICAL_TRIALS research · 2018-07-19Clinical Trial Update: The Use of CGMS to Detect Alterations of Blood Glucose in Thalassemic Patients [NA]
A completed clinical trial update examining the use of continuous glucose monitoring to detect blood glucose changes in patients with beta-t…
-
CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: A Study of EPEG in Beta Thalassemia Patients [Phase 1]
Phase 1 study of EPEG in beta-thalassemia patients has completed; results are not described in this update.
-
CLINICAL_TRIALS research · 2017-11-30Clinical Trial Update: Quality of Life and Treatment Satisfaction in β-Thalassemia Patients Receiving Deferasirox
An update on a clinical trial evaluating quality of life and treatment satisfaction in beta-thalassemia patients treated with deferasirox.
-
CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Gene Therapy of Beta Thalassemia Using a Self-inactivating Lentiviral Vector [NA]
This document is a clinical trial update for a beta-thalassemia gene therapy using a self-inactivating lentiviral vector, with the trial sta…
-
CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: The Efficacy and Safety of HYDROXYUREA in Management of Beta Thalassemia Patients in Karachi Pakistan [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of hydroxyurea in managing beta-thalassemia in Karachi, Pakistan.
-
CLINICAL_TRIALS trial_result · 2017-09-08Clinical Trial Update: Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically Modified [Phase 1, Phase 2]
Clinical trial update for autologous gene therapy for beta-thalassemia major in Phase 1/2.
-
CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias [Phase 2]
Phase 2 study of deferasirox for iron overload in beta-thalassemia patients who cannot be treated with deferoxamine, as well as related chro…
-
CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Genetic Factors Affecting the Severity of Beta Thalassemia
A completed clinical trial investigates how genetic factors influence the severity of beta-thalassemia.
-
CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Thalassemia Treatment Based on the Stem Cell Technology [NA]
This document provides a clinical trial update on a stem cell–based treatment for beta-thalassemia, but does not include status or result de…
-
CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: To Document the Burden of Illness on the Quality of Life and the Impact on Healthcare Utilization in (Beta) β-thalassemia Subjects Who Are Transfusion Dependent (TD) and Non-transfusion Dependent (NTD) Receiving Standard of Care
This completed clinical trial documents the burden of illness on quality of life and healthcare utilization among transfusion-dependent and …
-
CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis [Phase 3]
This clinical trial update announces the completion of a Phase 3 study evaluating deferasirox for long-term treatment in patients with beta-…
-
CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload [Phase 4]
Phase 4 trial assessing the efficacy of Deferasirox for iron chelation in transfusion-dependent chronic anemia due to myelodysplastic syndro…
-
CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients [NA]
This document reports a clinical trial evaluating amlodipine as an adjuvant to iron chelation to prevent cardiac iron overload in beta-thala…
-
CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia [Phase 2]
Phase 2 cord blood transplantation trial for sickle cell disease and beta-thalassemia has completed, with results reported from the complete…