Bap1 Tumor Predisposition Syndrome

• CLINICAL_TRIALS research · 2026-04-24
  Clinical Trial Update: Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

  This prospective study evaluates high-resolution dual-energy CT imaging, noninvasive liquid biopsies, and minimally invasive surveillance fo…

• CLINICAL_TRIALS trial_result · 2026-04-17
  Clinical Trial Update: Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma [Phase 2]

  A Phase 2 trial of INQOVI (decitabine/cedazuridine) in patients with BAP1 tumor predisposition syndrome and subclinical, early-stage mesothe…

• CLINICAL_TRIALS withdrawal · 2026-03-17
  Clinical Trial Update: Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma [Phase 2]

  Phase 2 trial of APG-115 (Alrizomadlin) for BAP1 tumor predisposition syndrome with mesothelioma has been withdrawn.

• CLINICAL_TRIALS research · 2026-03-09
  Clinical Trial Update: Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

  An ongoing clinical trial is recruiting to study the frequency and clinical phenotype of BAP1 tumor predisposition syndrome and its associat…

• CLINICAL_TRIALS research · 2025-12-19
  Clinical Trial Update: Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

  This study is recruiting long-term follow-up of mesothelioma patients and their family members who carry germline mutations in BAP1 and othe…

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