B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Sequential Infusion of Anti-CD19 and Anti-CD20 CAR-T Cells Against Relapsed and Refractory B-cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 study assessing sequential infusion of CD19- and CD20-directed CAR-T cells in relapsed or refractory B-cell lymphoma.
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CLINICAL_TRIALS research · 2017-06-23Clinical Trial Update: A Study Evaluating UCART019 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update on UCART019 for relapsed/refractory CD19+ leukemia and lymphoma (Phase 1/2) conducted by Chinese PLA General Hospital.
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CLINICAL_TRIALS other · 2017-05-17Clinical Trial Update: CD19 CART Cells for Patients With Relapse and Refractory CD19+ B-cell Lymphoma. [Phase 1, Phase 2]
This document provides an update on a Phase 1/Phase 2 clinical trial evaluating CD19 CAR-T cells in patients with relapse or refractory CD19…
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CLINICAL_TRIALS research · 2017-04-28Clinical Trial Update: CAR T Cells for Refractory B Cell Malignancy [Phase 1, Phase 2]
This entry reports an ongoing Phase 1/Phase 2 trial of CAR T cell therapy for refractory B-cell malignancies, including B-cell leukemia and …
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: The Safety and Efficacy of CART-19 Cells in Relapse and Refractory Patients With CD19+ B-cell Lymphoma [Phase 1]
This Phase 1 trial evaluates the safety and preliminary efficacy of CART-19 autologous CAR-T cells in patients with relapsed or refractory C…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Treatment of Aggressive Localized Lymphoma [Phase 3]
A Phase 3 clinical trial evaluating a treatment for aggressive localized B-cell lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed/Refractory Marginal Zone Lymphoma [Phase 2]
Phase 2 trial update for a Bruton's Tyrosine Kinase inhibitor in relapsed/refractory marginal zone lymphoma and B-cell lymphoma has complete…
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: Anti-CD19:TCRζ Chimeric Antigen Receptor-T Cells in the Treatment for CD19+ B Cell Lymphoma [Phase 4]
This document reports a Phase 4 clinical trial of anti-CD19:TCRζ CAR-T cells for CD19-positive B-cell lymphoma. The current status is UNKNOW…
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CLINICAL_TRIALS research · 2016-11-16Clinical Trial Update: Pilot Study of Anti-CD20-CAR-engineered T Cells in Patients With Chemotherapy Resistant or Refractory CD20+ Lymphoma [Phase 1, Phase 2]
Pilot Phase 1/2 clinical trial evaluating anti-CD20 CAR-T cells in patients with chemotherapy-resistant or refractory B-cell lymphoma. The t…
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CLINICAL_TRIALS withdrawal · 2016-10-14Clinical Trial Update: R-CHOP-B Bevacizumab for Diffuse Large B Cell Lymphoma [Phase 2]
A phase 2 trial of R-CHOP-B (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone plus Bevacizumab) for diffuse large B-cell ly…
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: CD19-redirected Autologous Cells (CAR-CD19 T Cells) [Phase 1]
Phase 1 clinical trial update on autologous CAR-CD19 T cells targeting CD19-positive malignant B-cell leukemia and lymphoma.
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial of Brentuximab Vedotin in relapsed or refractory non-Hodgkin lymphoma has completed and results have been posted. The study …
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CLINICAL_TRIALS trial_result · 2016-08-17Clinical Trial Update: Safety and Efficacy of Bexxar Therapy in the Treatment of Relapsed/Residual B-Cell Lymphoma After Autologous Transplant [Phase 1]
This Phase 1 trial update reports on the safety and preliminary efficacy of Bexxar (tositumomab) in patients with relapsed or residual B-cel…
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma) [Phase 1]
A Phase 1 clinical trial of ASP3026 in patients with advanced malignancies, including solid tumors and B-cell lymphoma, has completed.
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CLINICAL_TRIALS research · 2016-06-28Clinical Trial Update: Chimeric Antigen Receptor T Cells (CART) Therapy in Refractory/Relapsed B Cell Hematologic Malignancies [NA]
Clinical trial update regarding Chimeric Antigen Receptor T Cells (CART) therapy for refractory/relapsed B-cell hematologic malignancies.
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CLINICAL_TRIALS trial_result · 2016-06-24Clinical Trial Update: Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in Hematological Malignancies [Phase 1]
Phase 1 study of a dual PI3K Delta/Gamma inhibitor in B-cell and T-cell lymphomas has completed, assessing safety and preliminary efficacy.
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: High Dose, Absorbed Dose Adjusted 90Y-ibritumomab With Peripheral Blood Stem Cells (PBSC) Support in B-cell Lymphoma [Phase 1, Phase 2]
This clinical trial update reports the completion of Phase 1/2 testing of high-dose, absorbed-dose-adjusted 90Y-ibritumomab tiuxetan with pe…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Lower Dose Decitabine Based Therapy in Patients With Refractory and/or Chemotherapy Resistant Solid Tumors or B Cell Lymphomas [Phase 1, Phase 2]
Clinical trial update on a lower-dose decitabine-based therapy for patients with refractory or chemotherapy-resistant solid tumors and B-cel…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor
A completed clinical trial evaluated granulocyte-colony stimulating factor (G-CSF) for prevention of chemotherapy-induced febrile neutropeni…
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CLINICAL_TRIALS withdrawal · 2015-03-30Clinical Trial Update: A Phase I Study of Intrathecal Rituximab in Patients With Lymphomatous Meningitis [Phase 1]
The Phase I study of intrathecal rituximab for lymphomatous meningitis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-01-29Clinical Trial Update: Dose Escalation Study of Clofarabine in Patients With Relapsed or Refractory Low Grade or Intermediate-Grade B-Cell Lymphoma [Phase 1]
This Phase 1 dose-escalation trial evaluated clofarabine in patients with relapsed or refractory low-grade or intermediate-grade B-cell lymp…
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CLINICAL_TRIALS trial_result · 2014-12-30Clinical Trial Update: Study for Evaluation of Efficacy and Safety of SH L 749 to Indolent B-cell Non-Hodgkin's Lymphoma [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating the efficacy and safety of SH-L-749 in indolent B-cell non-Hodgk…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: A Phase I Study of the Chimeric Anti-CD40 Monoclonal Antibody ChiLob 7/4 to Treat Advanced Malignancies Refractory to Conventional Anti-cancer Treatment [Phase 1]
Phase I study of ChiLob 7/4, a chimeric anti-CD40 monoclonal antibody, in patients with advanced cancers refractory to conventional treatmen…
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CLINICAL_TRIALS research · 2014-10-20Clinical Trial Update: Evaluation of 4th Generation Safety-designed CAR T Cells Targeting High-risk and Refractory B Cell Lymphomas [Phase 1, Phase 2]
This update covers a Phase 1/Phase 2 evaluation of fourth-generation safety-designed CAR T cells targeting high-risk and refractory B-cell l…
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: AZD6738 First Time in Patient Multiple Ascending Dose Study [Phase 1]
AZD6738 (berzosertib) was studied in a first-in-patient, multiple ascending-dose Phase 1 trial in relapsed/refractory hematologic cancers in…