B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Combination of Rituximab and NK Immunotherapy for B Lymphoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating the combination of Rituximab with NK cell immunotherapy for recurrent B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a CD19 CAR-T cell therapy for treating B-cell malignancies, including acute lymphoblastic leukemia and…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Anti-CD19 CAR-T Therapy Bridging to HSCT for CD19+ B-Cell Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating anti-CD19 CAR-T therapy used as a bridging therapy to hematopoietic stem cell transplant for CD19…
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CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: Interleukin-7 and Chemokine (C-C Motif) Ligand 19-expressing CD19-CAR-T for Refractory/Relapsed B Cell Lymphoma. [Phase 2]
Phase 2 trial investigating IL-7 and CCL19-expressing CD19-CAR-T cells for refractory/relapsed B cell lymphoma; status and results not provi…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Study of Ibrutinib in Combination With Rituximab in Previously Untreated Subjects With Follicular Lymphoma [Phase 2]
Phase 2 trial evaluating ibrutinib in combination with rituximab in previously untreated follicular lymphoma shows completed status with pos…
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CLINICAL_TRIALS trial_result · 2019-03-15Clinical Trial Update: Study Evaluating The Safety And Tolerability Of Combination Therapy Inotuzumab Ozogamicin (CMC-544) And Rituximab [Phase 1]
Phase 1 study evaluating safety and tolerability of the combination of Inotuzumab Ozogamicin (CMC-544) and rituximab in lymphoma, B-cell ind…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Novel Autologou CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma [Phase 2]
This entry provides an update on a Phase 2 clinical trial of a novel autologous CAR-T therapy for relapsed/refractory B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell Lymphoma [Phase 1]
Phase 1 study of KA2237, a PI3K p110β/δ inhibitor, in B-cell lymphoma reports on safety, pharmacokinetics and pharmacodynamics.
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Study of ET190L1 ARTEMIS™ T Cells in Relapsed and Refractory CD19+ Non-Hodgkin's Lymphoma [Phase 1]
The Phase 1 study of ET190L1 ARTEMIS T Cells in relapsed and refractory CD19+ non-Hodgkin lymphoma has been terminated.
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CLINICAL_TRIALS research · 2019-01-31Clinical Trial Update: Study of Anti-CD19 iCAR NK Cells in Relapsed and Refractory B Cell Lymphoma [EARLY_Phase 1]
An early-phase 1 study evaluating anti-CD19 iCAR NK cells for relapsed and refractory B-cell lymphoma. The current sponsor-reported status i…
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CLINICAL_TRIALS research · 2019-01-31Clinical Trial Update: Study of Anti-CD19/CD22 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating anti-CD19/CD22 CAR NK cells in relapsed and refractory B-cell lymphoma; the current status is …
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Study of Anti-CD19 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma [EARLY_Phase 1]
An early Phase 1 study evaluating anti-CD19 CAR NK cells in relapsed and refractory B-cell lymphoma. The current trial status is unknown.
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CLINICAL_TRIALS research · 2019-01-30Clinical Trial Update: Study of Anti-CD22 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial investigating anti-CD22 CAR NK cells for relapsed and refractory B-cell lymphoma; the study status i…
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Anti-CD19 CAR-T Therapy Combine With HSCT to Treat MRD+ B-cell Malignancies [Phase 1, Phase 2]
A clinical trial update describes an anti-CD19 CAR-T therapy combined with hematopoietic stem cell transplantation for MRD-positive B-cell m…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: Association of Velcade to R-CHOP in the Treatment of B Cell Lymphoma [Phase 2]
A Phase 2 trial evaluating Velcade in combination with R-CHOP for B cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Optimized Donor Selection, Nonmyeloablative BMT for B-cell Lymphomas With Post-transplantation Cy and Rituximab [Phase 2]
Phase 2 trial update on optimized donor selection with nonmyeloablative bone marrow transplant using post-transplant cyclophosphamide and ri…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: The Clinical Research of Anti-CD20 CAR-T Cells in Patients With Refractory or Relapsed B Lymphocyte Lymphoma [Phase 1]
This document summarizes a Phase 1 trial evaluating anti-CD20 CAR-T cell therapy in patients with relapsed or refractory B-cell lymphoma. Th…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: CD19-targeted CAR-T Cell Therapy for MRD+ B-cell Malignancies After Autologous Stem Cell Transplantation [NA]
This clinical trial update discusses a CD19-targeted CAR-T cell therapy approach for minimal residual disease–positive B-cell lymphoma or le…
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CLINICAL_TRIALS research · 2018-05-30Clinical Trial Update: Cytoplasmic Activated PD-1 CAR T Cells in Refractory/Relapsed B Cell Lymphoma [Phase 1]
Phase 1 clinical trial update on Cytoplasmic Activated PD-1 CAR T Cells for relapsed/refractory B-cell non-Hodgkin lymphoma.
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Study Evaluating Inotuzumab Ozogamicin [CMC-544] Administered In Combination With Rituximab In Subjects With Non-Hodgkin's Lymphoma (NHL) [Phase 1, Phase 2]
Phase 1/2 study evaluating inotuzumab ozogamicin (CMC-544) in combination with rituximab in patients with B-cell non-Hodgkin lymphoma; resul…
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: A Phase IB Study Of The BTKi CC-292 Combined With Lenalidomide In Adults Patients With Relapsed/Refractory B-Cell Lymphoma [Phase 1]
A Phase 1B trial assessing the BTK inhibitor CC-292 in combination with lenalidomide in adults with relapsed/refractory B-cell lymphoma has …
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: A Feasibility and Safety Study of Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cell Immunotherapy for Relapsed or Refractory Leukemia and Lymphoma [Phase 1, Phase 2]
A feasibility and safety study evaluating universal dual-specificity CAR-T cells targeting CD19/CD20 or CD22 for relapsed or refractory B ce…
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: CD19-targeting 3rd Generation CAR T Cells for Refractory B Cell Malignancy - a Phase I/IIa Trial. [Phase 1, Phase 2]
A Phase I/IIa trial evaluating CD19-targeting third-generation CAR T cells for refractory B-cell malignancies has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Vaccination of Follicular Lymphomas With Tumor-Derived Immunoglobulin Idiotype [Phase 1]
A Phase 1 clinical trial evaluating vaccination with tumor-derived immunoglobulin idiotype for follicular lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Active Specific Immunotherapy for Follicular Lymphomas With Tumor-Derived Immunoglobulin Idiotype Antigen Vaccines [Phase 1]
A Phase 1 trial evaluated a tumor-derived immunoglobulin idiotype antigen vaccine for follicular lymphoma. The trial status indicates comple…