Autosomal Dominant Polycystic Kidney Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Dose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD [Phase 2]
Phase 2 dose-finding study evaluating a new formulation of tolvaptan in adults with autosomal dominant polycystic kidney disease; results we…
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CLINICAL_TRIALS research · 2018-05-14Clinical Trial Update: Dynamic Measurement of Renal Functional Reserve as a Predictor of Long-Term Renal Function [NA]
A clinical trial update exploring dynamic measurement of renal functional reserve to predict long-term kidney function, in adults with polyc…
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FDA approval · 2018-04-23FDA Approved: JYNARQUE — Original Application (Otsuka America Pharmaceutical, Inc.)
The FDA approved JYNARQUE (tolvaptan) from Otsuka for autosomal dominant polycystic kidney disease, marking the first drug approved to slow …
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CLINICAL_TRIALS trial_result · 2018-03-20Clinical Trial Update: The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease [NA]
This clinical trial update reports the completion of a study evaluating the impact of high and low sodium intake on urinary Aquaporin-2 leve…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Efficacy Study of Water Drinking on PKD Progression.
A completed clinical trial evaluating whether increased water intake affects progression of autosomal dominant polycystic kidney disease.
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 3]
Phase 3 trial evaluating the effect of statin therapy on disease progression in autosomal dominant polycystic kidney disease completed with …
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency [Phase 3]
Phase 3 clinical trial in autosomal dominant polycystic kidney disease with moderate to severe renal insufficiency has completed.
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Autosomal Dominant Polycystic Kidney Disease (ADPKD) Pain Study [NA]
The Mayo Clinic-sponsored clinical trial evaluating pain in autosomal dominant polycystic kidney disease has completed.
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CLINICAL_TRIALS research · 2017-08-17Clinical Trial Update: Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease
The CRISP study (NCT01039987) investigating radiologic imaging in Autosomal Dominant Polycystic Kidney Disease has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of tolvaptan in autosomal dominant polycystic kidney disease has completed, with results …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 2]
Open-label Phase 2 pilot study evaluating tolvaptan for efficacy, tolerability, and safety in autosomal dominant polycystic kidney disease. …
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Short-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 2]
Phase 2 trial update evaluating short-term renal hemodynamic effects of tolvaptan in autosomal dominant polycystic kidney disease.
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CLINICAL_TRIALS research · 2017-05-23Clinical Trial Update: Study of Lanreotide to Treat Polycystic Kidney Disease [Phase 3]
Phase 3 clinical trial evaluating lanreotide for autosomal dominant polycystic kidney disease, sponsored by University Medical Center Gronin…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease [Phase 2, Phase 3]
This clinical trial update notes completed Phase 2 and Phase 3 studies investigating diet as a potential treatment for Autosomal Dominant Po…
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CLINICAL_TRIALS withdrawal · 2017-03-29Clinical Trial Update: Repository Study of Autosomal Dominant Polycystic Kidney Disease
The repository study for autosomal dominant polycystic kidney disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Clinical Implications of DNA Analysis on ADPKD
A completed clinical trial update evaluating the clinical implications of DNA analysis for Autosomal Dominant Polycystic Kidney Disease (ADP…
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Effect of the Aquaretic Tolvaptan on Nitric Oxide System [Phase 2]
A Phase 2 trial evaluating tolvaptan's effect on the nitric oxide system in autosomal dominant polycystic kidney disease has completed.
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CLINICAL_TRIALS research · 2016-09-02Clinical Trial Update: Analysis of Clinical and Molecular Genetic Data Influencing the Evolution and Response to Therapy of ADPKD Patients (Autosomal Dominant Polycystic Kidney Disease)
Clinical trial update focusing on how clinical and molecular genetic data influence the evolution and response to therapy in autosomal domin…
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CLINICAL_TRIALS trial_result · 2016-06-17Clinical Trial Update: New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease
A completed Mayo Clinic-backed clinical trial evaluated new quantitative MRI parameters to assess kidney involvement in autosomal dominant p…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: High Water Intake to Slow Progression of Polycystic Kidney Disease [NA]
A completed trial examined whether high water intake could slow the progression of autosomal dominant polycystic kidney disease; results wer…
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CLINICAL_TRIALS trial_result · 2015-10-28Clinical Trial Update: Bosutinib For Autosomal Dominant Polycystic Kidney Disease [Phase 2]
A Phase 2 trial of bosutinib for autosomal dominant polycystic kidney disease has completed, and results were posted in October 2015.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: A New Diet for Patients With Autosomal Dominant Polycystic Disease (ADPKD) [NA]
A University of Kansas-sponsored trial tested a new diet for autosomal dominant polycystic kidney disease and has completed.
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: ADPKD Cohort Study
An Emory University–sponsored cohort study on Autosomal Dominant Polycystic Kidney Disease has completed.
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CLINICAL_TRIALS trial_result · 2015-06-23Clinical Trial Update: Everolimus on CKD Progression in ADPKD Patients [Phase 2, Phase 3]
A Phase 2/Phase 3 trial of everolimus for slowing CKD progression in autosomal dominant polycystic kidney disease has been terminated.
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: The Eurocyst Initiative: Building a Network of ADPKD Reference Centers Across Europe
An update on the Eurocyst Initiative to create a Europe-wide network of ADPKD reference centers. The sponsor is Andreas L. Serra, and the cu…