Autosomal Dominant Polycystic Kidney Disease
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CLINICAL_TRIALS trial_result · 2023-02-06Clinical Trial Update: Study of the Efficacy and Safety of Tesevatinib in Subjects With ADPKD [Phase 2]
Phase 2 trial evaluating the efficacy and safety of tesevatinib in autosomal dominant polycystic kidney disease (ADPKD) has completed with r…
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CLINICAL_TRIALS trial_result · 2023-02-06Clinical Trial Update: Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease [Phase 3]
Clinical trial update for lixivaptan in autosomal dominant polycystic kidney disease (ADPKD) in Phase 3; the study was terminated with resul…
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CLINICAL_TRIALS trial_result · 2023-01-03Clinical Trial Update: Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease) [Phase 3]
Phase 3 trial evaluating tolvaptan in children and adolescents with autosomal dominant polycystic kidney disease has completed with posted r…
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CLINICAL_TRIALS trial_result · 2022-12-05Clinical Trial Update: The ELiSA Study - Evaluation of Lixivaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
Phase 2 study evaluating lixivaptan for autosomal dominant polycystic kidney disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-11-08Clinical Trial Update: A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease [Phase 1, Phase 2]
Phase 1/2 study of KD019 in autosomal dominant polycystic kidney disease completed; safety, pharmacokinetics, and dose-escalation results ha…
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Tolvaptan-Octreotide LAR Combination in ADPKD [Phase 2]
Phase 2 trial update evaluating a Tolvaptan-Octreotide LAR combination in autosomal dominant polycystic kidney disease has completed.
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CLINICAL_TRIALS trial_result · 2022-10-06Clinical Trial Update: Long-term Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) With Venglustat [Phase 3]
Phase 3 trial of venglustat for Autosomal Dominant Polycystic Kidney Disease has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2022-08-09Clinical Trial Update: Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease [Phase 2]
Phase 2 clinical trial investigating metformin as a novel therapy for autosomal dominant polycystic kidney disease has completed with result…
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CLINICAL_TRIALS trial_result · 2022-06-16Clinical Trial Update: Evaluating the Safety and effectivenesS in Adult KorEaN Patients Treated With Tolvaptan for Management of Autosomal domInAnt poLycystic Kidney Disease [Phase 4]
Phase 4 clinical trial evaluating safety and effectiveness of tolvaptan in adult Korean patients with autosomal dominant polycystic kidney d…
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CLINICAL_TRIALS trial_result · 2022-01-18Clinical Trial Update: A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX [Phase 2]
Phase 2 trial evaluating bardoxolone methyl in rare chronic kidney diseases has completed, with results posted January 18, 2022. Diseases st…
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: Tolvaptan Extension Study in Participants With ADPKD [Phase 3]
Phase 3 extension study update for Tolvaptan in autosomal dominant polycystic kidney disease (ADPKD) with completed status and results poste…
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CLINICAL_TRIALS trial_result · 2020-03-02Clinical Trial Update: Pasireotide LAR in Severe Polycystic Liver Disease [Phase 2]
Phase 2 clinical trial of pasireotide LAR in severe polycystic liver disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 3]
Phase 3 clinical trial update on mineralocorticoid antagonism and endothelial dysfunction in autosomal dominant polycystic kidney disease (A…
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CLINICAL_TRIALS trial_result · 2019-01-17Clinical Trial Update: A Study to Investigate the Long-term Safety and Efficacy of Tolvaptan in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Trial 156-04-251 in Japan] [Phase 3]
This clinical trial update reports long-term safety and efficacy results from an extension of a Phase 3 study of tolvaptan in autosomal domi…
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CLINICAL_TRIALS trial_result · 2018-12-10Clinical Trial Update: The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients [Phase 3]
Phase 3 trial evaluating everolimus for reducing total native kidney volume in recipients with autosomal dominant polycystic kidney disease …
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: Metformin vs Tolvaptan for Treatment of Autosomal Dominant Polycystic Kidney Disease [Phase 3]
A Phase 3 trial comparing metformin to tolvaptan for autosomal dominant polycystic kidney disease is in progress, with status currently unkn…
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Subacute Effect of Tolvaptan on Total Kidney Volume in Adult Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 4]
Phase 4 clinical trial update evaluating subacute effect of Tolvaptan on total kidney volume in adults with autosomal dominant polycystic ki…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease [Phase 3]
A Phase 3 clinical trial update for pulsed oral sirolimus in autosomal dominant polycystic kidney disease is reported, with status currently…
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: 8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 2]
Phase 2 trial update for tolvaptan dose forms in autosomal dominant polycystic kidney disease (ADPKD) with completed status and results post…
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CLINICAL_TRIALS trial_result · 2018-08-08Clinical Trial Update: Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease [Phase 3]
Phase 3 trial assessing efficacy and safety of tolvaptan in adults with autosomal dominant polycystic kidney disease (late stage 2 to early …
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) (2) [Extension of Study 156-05-002] [Phase 3]
Phase 3 long-term extension study of OPC-41061 in autosomal dominant polycystic kidney disease (ADPKD) completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001] [Phase 2]
Phase 2 long-term administration study extension for OPC-41061 in autosomal dominant polycystic kidney disease completed with results posted…
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Dose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD [Phase 2]
Phase 2 dose-finding study evaluating a new formulation of tolvaptan in adults with autosomal dominant polycystic kidney disease; results we…
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CLINICAL_TRIALS trial_result · 2018-03-20Clinical Trial Update: The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease [NA]
This clinical trial update reports the completion of a study evaluating the impact of high and low sodium intake on urinary Aquaporin-2 leve…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Efficacy Study of Water Drinking on PKD Progression.
A completed clinical trial evaluating whether increased water intake affects progression of autosomal dominant polycystic kidney disease.