Autosomal Dominant Polycystic Kidney Disease
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease
A clinical trial update on PKD1 gene variant groups in autosomal dominant polycystic kidney disease, sponsored by Vertex, with the study cur…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Lanreotide In Polycystic Kidney Disease Study [Phase 3]
A Phase 3 clinical trial evaluating lanreotide for autosomal dominant polycystic kidney disease (ADPKD) has completed.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Phase 1 Study Evaluating Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants [Phase 1]
A Phase 1 clinical trial evaluating VX-407 for safety, tolerability, and pharmacokinetics in healthy participants has completed, with Autoso…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: A Possible Founding PKD2 Mutation Associated With Variable Phenotypes of ADPKD in Bergamo Province
A completed clinical trial from the Mario Negri Institute reports a potential founder PKD2 mutation associated with variable phenotypes in A…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Mass Balance and Absolute Bioavailability Study of JMKX003142 In Healthy Volunteers [Phase 1]
A Phase 1 mass-balance and absolute bioavailability study of the investigational drug JMKX003142 in healthy volunteers to characterize pharm…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Safety of RotigotiNe in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
A Phase 2 trial safety update for RotigotiNe in autosomal dominant polycystic kidney disease, with the study not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Probenecid (PB) to Treat Hereditary Nephrogenic Diabetes Insipidus (NDI), ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration [Phase 2]
Phase 2 clinical trial evaluating probenecid for hereditary nephrogenic diabetes insipidus, with autosomal dominant polycystic kidney diseas…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Descriptive Analysis of Preimplantation Genetic Test (PGT)in Couples With Polycystic Kidney Disease (PKD). In the ADPKD Subgroup Evaluation of Outcomes and Complications Comparing Couples in Which the Father is Affected With Couples in Which the Mother is Affected
This completed clinical trial update provides a descriptive analysis of preimplantation genetic testing (PGT) in couples affected by autosom…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD
Post-marketing surveillance study of tolvaptan in autosomal dominant polycystic kidney disease has completed and posted its results.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Outcome of ADPKD With Octreotide LAR
An update on a clinical trial evaluating octreotide long-acting release for autosomal dominant polycystic kidney disease (ADPKD). The trial …
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Treatment of Vascular Stiffness in ADPKD [Phase 4]
A Phase 4 clinical trial evaluating treatments for vascular stiffness in autosomal dominant polycystic kidney disease has completed.
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
A Phase 2 clinical trial evaluating pravastatin with alkali therapy in adults with autosomal dominant polycystic kidney disease has complete…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Samsca PMS in ADPKD Patients
A completed post-marketing safety surveillance study of Samsca (tolvaptan) in patients with autosomal dominant polycystic kidney disease.
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease [NA]
This completed clinical trial evaluated the effect of beetroot juice on reducing hypertension in autosomal dominant polycystic kidney diseas…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating the safety and pharmacology of RGLS8429 in adults with autosomal domi…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Feasibility of Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
Phase 2 feasibility study of empagliflozin in autosomal dominant polycystic kidney disease; the trial is currently active but not recruiting…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Study of Tamibarotene in Patients With ADPKD [Phase 2]
Phase 2 clinical trial evaluating tamibarotene for Autosomal Dominant Polycystic Kidney Disease (ADPKD) is currently active but not recruiti…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Genetic Testing in Autosomal Dominant Polycystic Kidney Disease
A completed clinical trial update reporting results from genetic testing in autosomal dominant polycystic kidney disease.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Renal Denervation in ADPKD- RDN-ADPKD Study [NA]
The Renal Denervation in Autosomal Dominant Polycystic Kidney Disease (ADPKD) study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 2]
Phase 2 study evaluating GLPG2737 for Autosomal Dominant Polycystic Kidney Disease was terminated, with results posted on 2024-08-22.
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON [Phase 3]
Phase 3 trial of bardoxolone methyl in autosomal dominant polycystic kidney disease was terminated with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE) [Phase 3]
The Phase 3 extended access program for bardoxolone methyl in chronic kidney disease was terminated, with results posted in March 2024. The …
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Treat Autosomal Dominant Polycystic Kidney Disease With Oral Ketone Ester? [Phase 2]
Phase 2 clinical trial exploring an oral ketone ester for autosomal dominant polycystic kidney disease (ADPKD).
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Atorvastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
Phase 2 clinical trial investigating atorvastatin with alkali therapy in autosomal dominant polycystic kidney disease and chronic kidney dis…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease [Phase 3]
Phase 3 trial assessing safety of lixivaptan in adults with autosomal dominant polycystic kidney disease previously treated with tolvaptan; …