Autonomic Failure
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CLINICAL_TRIALS trial_result · 2026-08-07Clinical Trial Results: Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients [EARLY_Phase 1]
Early-phase trial comparing midodrine to abdominal compression in autonomic failure patients assessing cardiovascular risk markers.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: CPAP for the Treatment of Supine Hypertension [NA]
This clinical trial update indicates that a study is recruiting to evaluate CPAP for the treatment of supine hypertension in autonomic failu…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: [18F]F-DOPA Imaging in Patients With Autonomic Failure [Phase 1]
Phase 1 imaging trial of [18F]F-DOPA in autonomic failure syndromes (including Parkinson's disease, multiple system atrophy, and dementia wi…
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CLINICAL_TRIALS other · 2026-01-16Clinical Trial Update: Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension [NA]
Ongoing clinical trial assessing overnight heat-stress effects in autonomic failure patients with supine hypertension; recruitment is curren…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients [EARLY_Phase 1]
A Phase 1 clinical trial is evaluating midodrine versus abdominal compression for cardiovascular risk markers in autonomic failure, and the …
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Automated Abdominal Binder for Orthostatic Hypotension [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating an automated abdominal binder to treat orthostatic hypotension is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure [NA]
A clinical trial is investigating whether raising the head of the bed affects lying blood pressure in people with autonomic failure and its …
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Treatment of Supine Hypertension in Autonomic Failure (CPAP) [NA]
This entry notes a clinical trial evaluating CPAP therapy for treating supine hypertension in patients with autonomic failure, and the study…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure [Phase 1]
Phase 1 clinical trial evaluating the effects of midodrine and droxidopa on splanchnic capacitance in autonomic failure; currently recruitin…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms [NA]
This clinical trial update describes a Vanderbilt-led study evaluating accelerometer-based quantification of symptoms in neurogenic orthosta…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System
Enrollment by invitation is ongoing for a prodromal Parkinson's disease model confined to the peripheral nervous system.
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: CO2 Rebreathing in nOH: A Proof-of-Concept Pilot Study [NA]
The clinical trial update reports a proof-of-concept pilot study on CO2 rebreathing for neurogenic orthostatic hypotension and autonomic fai…
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CLINICAL_TRIALS trial_result · 2022-11-30Clinical Trial Update: Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure [Phase 3]
Phase 3 open-label extension studying TD-9855 for symptomatic neurogenic orthostatic hypotension due to primary autonomic failure was termin…
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CLINICAL_TRIALS trial_result · 2022-09-14Clinical Trial Update: Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure [Phase 3]
Phase 3 trial assessing ampRELOXetine (TD-9855) for symptomatic neurogenic orthostatic hypotension due to primary autonomic failure has comp…
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: Local Heat Stress in Autonomic Failure Patients With Supine Hypertension [NA]
Clinical trial about local heat stress in autonomic failure patients with supine hypertension has completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-14Clinical Trial Update: Mechanisms of Hypoglycemia Associated Autonomic Failure [Phase 2]
Phase 2 clinical trial update on mechanisms of hypoglycemia-associated autonomic failure in diabetes patients.
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Treatment of Orthostatic Hypotension in Autonomic Failure [Phase 1]
A Phase 1 clinical trial at Vanderbilt University evaluating treatment for orthostatic hypotension in autonomic failure has completed.
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) [Phase 3]
This update reports the Phase 3 results of droxidopa in patients with symptomatic neurogenic orthostatic hypotension.
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CLINICAL_TRIALS trial_result · 2014-05-16Clinical Trial Update: A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa [Phase 3]
Phase 3 clinical trial of droxidopa for neurogenic orthostatic hypotension has completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: Abdominal Compression in Orthostatic Hypotension [NA]
This clinical trial update reports the completion of a Mayo Clinic-sponsored study evaluating abdominal compression as a treatment for ortho…
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304) [Phase 3]
Phase 3 clinical study of droxidopa (NOH) completed; results posted in 2014 for patients with neurogenic orthostatic hypotension and related…