Atypical Hemolytic Uremic Syndrome
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS [Phase 4]
Phase 4 post-marketing clinical trial evaluating ravulizumab in patients with atypical Hemolytic Uremic Syndrome (aHUS) is currently recruit…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS) [Phase 3]
Phase 3 trial update describes switching study participants with atypical hemolytic uremic syndrome from anti-C5 antibody therapy to iptacop…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Ravulizumab Outcomes in Polish Patients With aHUS
A clinical trial evaluating ravulizumab outcomes in Polish patients with atypical hemolytic uremic syndrome is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome [Phase 3]
A Phase 3 safety and efficacy trial of OMS721 in patients with atypical hemolytic uremic syndrome has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Eculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in China [Phase 3]
Phase 3 trial of eculizumab in pediatric and adult participants with atypical hemolytic uremic syndrome in China has completed and results w…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU) [Phase 3]
A Phase 3 trial evaluating personalized spacing of eculizumab infusions guided by therapeutic pharmacological monitoring in atypical hemolyt…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea
A retrospective study from South Korea evaluates clinical outcomes in atypical hemolytic uremic syndrome patients according to the treatment…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients [Phase 2]
Phase 2 clinical trial update evaluating eculizumab for thrombotic microangiopathy/atypical hemolytic uremic syndrome–associated multiple or…
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Study of Ravulizumab in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS) [Phase 3]
Phase 3 trial in children and adolescents with atypical hemolytic uremic syndrome (aHUS) completed, with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS) [Phase 3]
Phase 3 trial of ALXN1210 in treatment-naïve adults and adolescents with atypical hemolytic uremic syndrome has completed with results poste…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Evaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and Treatment
A terminated clinical trial investigating predictors of disease progression in atypical hemolytic uremic syndrome, including genetics and bi…
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CLINICAL_TRIALS trial_result · 2019-12-06Clinical Trial Update: Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS [Phase 4]
Phase 4 study evaluating an algorithm-based strategy for discontinuing eculizumab in children and adults with atypical hemolytic uremic synd…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS) [Phase 2]
Phase 2 trial assessing the safety and efficacy of eculizumab in Japanese patients with atypical hemolytic uremic syndrome (aHUS) has comple…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: aHUS Observational Long Term Follow-Up
An observational long-term follow-up trial for atypical hemolytic uremic syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome [Phase 2]
This update reports results from an open-label, multicenter Phase 2 trial of eculizumab in pediatric patients with atypical hemolytic-uremic…
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CLINICAL_TRIALS trial_result · 2015-04-24Clinical Trial Update: An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome [Phase 2]
Phase 2 open-label, multi-center trial of eculizumab in adults with atypical hemolytic uremic syndrome has completed and results were posted…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS) [Phase 2]
Phase 2 open-label trial evaluating eculizumab in adult patients with plasma therapy-sensitive atypical Hemolytic Uremic Syndrome; results w…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS [Phase 2]
Open-label Phase 2 trial of the complement inhibitor eculizumab in adolescent patients with plasma therapy–sensitive atypical hemolytic urem…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS [Phase 2]
This ClinicalTrials.gov update reports results from a Phase 2 open-label controlled trial of eculizumab in adolescents with plasma-therapy-r…
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CLINICAL_TRIALS trial_result · 2014-12-01Clinical Trial Update: Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS [Phase 2]
Phase 2 open-label trial of eculizumab in adult patients with plasma therapy-resistant atypical hemolytic uremic syndrome completed, with re…
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CLINICAL_TRIALS trial_result · 2012-12-24Clinical Trial Update: To Characterize the Safety and Tolerability of Eculizumab in Two Japanese aHUS Patients
This update reports on the safety and tolerability of eculizumab in two Japanese patients with atypical hemolytic uremic syndrome (aHUS). Th…