Atherosclerotic Cardiovascular Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients. [Phase 3]
Phase 3 clinical trial evaluating Inclisiran to prevent cardiovascular events in high-risk individuals for primary prevention of atheroscler…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis [Phase 2]
A Phase 2 clinical trial is evaluating IL-1β inhibition to reduce vascular inflammation in individuals with TET2 clonal hematopoiesis; the s…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD [Phase 3]
Phase 3 clinical trial update for pelacarsen (TQJ230) evaluating Lp(a) lowering in Black/African American and Hispanic participants with ele…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Observational Study of ASCVD Risks of Type 2 Diabetes in East China
This completed observational study in East China examines ASCVD risk in individuals with type 2 diabetes, with data related to liraglutide e…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages [NA]
This clinical trial from the National University Health System, Singapore, is recruiting to test whether temporal self-regulation theory-bas…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial sponsored by Brigham and Women's Hospital is recruiting to prevent cardiovascular disease and diabetic kidney disea…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis [Phase 2]
Phase 2 study evaluating ABP-745 for efficacy, safety, and population pharmacokinetics in patients with atherosclerosis and ASCVD.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis [Phase 2, Phase 3]
Clinical trial update describing a combined dose-finding and cardiovascular outcomes study of CSL300 (clazakizumab) in adults with end-stage…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
Verve Therapeutics reports long-term follow-up data from participants treated with its investigational gene-editing therapy for cardiovascul…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD [Phase 3]
A Phase 3 study is evaluating whether lowering lipoprotein(a) with pelacarsen (TQJ230) reduces major cardiovascular events in patients with …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVD [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating TB-500 (Thymosin Beta-4 17-23 fragment) for cardiovascular biomarkers in stable atherosclerotic car…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a) [Phase 2]
Phase 2 clinical trial to evaluate Kylo-11 in patients with atherosclerotic cardiovascular disease and elevated lipoprotein(a) is currently …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of the Determinants of Coronary Atherosclerosis in Familial Hypercholesterolemia (ATHERO-FH Study) [NA]
Enrollment is ongoing for the ATHERO-FH Study, a clinical trial investigating determinants of coronary atherosclerosis in people with famili…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Impact of the Corrie Lipids Digital Health Program on Lipid Optimization [NA]
An ongoing Johns Hopkins University study is evaluating the Corrie Lipids digital health program to optimize lipid management and reduce LDL…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Comparative Effects of Carnivore and Mediterranean-style Diets on LDL Aggregation and Cardiometabolic Health [NA]
This clinical trial compares carnivore- and Mediterranean-style diets to evaluate their effects on LDL aggregation and cardiometabolic healt…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: The Belgian REAL (BE.REAL) Registry
The BE.REAL Belgian registry update for Atherosclerotic Cardiovascular Disease is sponsored by Novartis, and the registry is currently activ…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon [Phase 4]
Phase 4 MIRAGE study evaluating the Mamba sirolimus-eluting PTCA balloon for coronary artery disease has completed, reporting clinical outco…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Optimizing Non-statin Agents for ASCVD
This clinical trial update shows a University of Texas at Austin study recruiting participants to optimize non-statin therapies for managing…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial [Phase 3]
The update concerns the Phase 3 OCEAN(a) outcomes trial evaluating olpasiran to reduce lipoprotein(a)-driven cardiovascular events in patien…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: ASCVD Management Using CCTA in Prostate Cancer Patients on ADT [NA]
A clinical trial is recruiting to evaluate using coronary CT angiography to manage ASCVD risk in prostate cancer patients undergoing androge…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Patients [EARLY_Phase 1]
Early-phase, placebo-controlled study to evaluate single and multiple ascending doses of UDP-003 in healthy participants and patients with a…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors [NA]
A Duke University trial evaluating cardiometabolic prevention strategies for high-risk cardiovascular patients with uncontrolled risk factor…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease
A clinical trial evaluating evolocumab (Repatha) plus standard of care versus standard of care alone on major cardiovascular events in Chine…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
This clinical trial update describes INTERCEPT-ASCVD, a Brigham and Women's Hospital study evaluating incretin-based therapies for cardiovas…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure [Phase 2]
Phase 2 study of AZD0780 evaluating effect on ambulatory blood pressure in patients with atherosclerotic cardiovascular disease has complete…