Atherosclerotic Cardiovascular Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia [Phase 2]
Phase 2 study of olezarsen (formerly AKCEA-APOCIII-LRx) in adults with hypertriglyceridemia and atherosclerotic cardiovascular disease or se…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a) [Phase 3]
Phase 3 study evaluating Muvalaplin for reducing major cardiovascular events in adults with elevated lipoprotein(a) and ASCVD. The trial is …
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD [Phase 3]
Phase 3 clinical trial update evaluating Lp(a) lowering with pelacarsen (TQJ230) plus background inclisiran in participants with elevated Lp…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease [Phase 3]
Phase 3 clinical trial update for inclisiran to prevent cardiovascular events in people with established atherosclerotic cardiovascular dise…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD [Phase 3]
Phase 3 clinical trial update for pelacarsen (TQJ230) evaluating Lp(a) lowering in Black/African American and Hispanic participants with ele…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
Verve Therapeutics reports long-term follow-up data from participants treated with its investigational gene-editing therapy for cardiovascul…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a) [Phase 2]
Phase 2 clinical trial to evaluate Kylo-11 in patients with atherosclerotic cardiovascular disease and elevated lipoprotein(a) is currently …
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon [Phase 4]
Phase 4 MIRAGE study evaluating the Mamba sirolimus-eluting PTCA balloon for coronary artery disease has completed, reporting clinical outco…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial [Phase 3]
The update concerns the Phase 3 OCEAN(a) outcomes trial evaluating olpasiran to reduce lipoprotein(a)-driven cardiovascular events in patien…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure [Phase 2]
Phase 2 study of AZD0780 evaluating effect on ambulatory blood pressure in patients with atherosclerotic cardiovascular disease has complete…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia [Phase 3]
Phase 3 clinical trial of olezarsen (ISIS 678354) in participants with hypertriglyceridemia and atherosclerotic cardiovascular disease, or w…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Step-Aerobics Versus Core Exercise for Non-HDL Cholesterol Reduction in Sedentary Women [NA]
A completed trial compared step-aerobics versus core exercise for reducing non-HDL cholesterol in sedentary women.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease. [Phase 4]
Phase 4 trial comparing LDL-cholesterol lowering with Inclisiran versus Bempedoic acid in patients with atherosclerotic cardiovascular disea…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Comparative Study Between Antihyperlipidemic Agents in Treatment of Cardiovascular Diseases [Phase 2, Phase 3]
This document reports the completion of a Phase 2/3 comparative trial of antihyperlipidemic agents for cardiovascular diseases. The sponsor …
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Lipoprotein (a) and Vascular Regenerative Cell Content
This clinical trial update indicates completion of a study examining lipoprotein(a) and vascular regenerative cell content sponsored by the …
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Barriers to Optimal LDL-C Targets in Patients With Atherosclerotic Cardiovascular Disease
This completed clinical trial investigates barriers to achieving target LDL-C levels in patients with coronary artery disease and other athe…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease. [Phase 1]
A Phase 1b study evaluating AZD4144 in participants with established atherosclerotic cardiovascular disease and chronic kidney disease has c…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial [NA]
A randomized Ez-PAVE trial in patients with atherosclerotic cardiovascular disease compares LDL-C targets of <70 mg/dL versus <55 mg/dL usin…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Study of HRS-5346 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events [Phase 2]
Phase 2 study evaluating HRS-5346 in adults with elevated lipoprotein(a) at high cardiovascular risk has completed.
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease [Phase 4]
Clinical trial update for VictORION-INCLUSION, a Phase 4 study evaluating inclisiran for cholesterol management in patients with atheroscler…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)
A completed trial comparing tirzepatide to sitagliptin in adults with type 2 diabetes and cardiovascular risk evaluates comparative effectiv…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies [Phase 3]
Phase 3 study evaluating a fixed-dose combination of obicetrapib and ezetimibe added to existing lipid-modifying therapy has completed. Resu…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Protective Effect of 5-Alpha Reductase Inhibitors on Atherosclerotic Cardiovascular Disease in Populations With BPH: Evidence From UK Biobank Cohort and Chinese Single Center Database Studies
Completed analyses from UK Biobank and a Chinese single-center database suggest that use of 5-alpha reductase inhibitors may be associated w…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies [Phase 3]
Phase 3 randomized study evaluating obicetrapib added to maximum tolerated lipid-modifying therapies has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients [Phase 4]
Phase 4 trial evaluating the effectiveness and safety of adding ezetimibe early to atorvastatin in very high-risk patients with atherosclero…