Astrocytoma Idh-mutant
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma [Phase 1]
A Phase 1 trial evaluating Triapine in combination with radiation therapy for recurrent glioblastoma or astrocytoma has been suspended.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas [Phase 1, Phase 2]
Clinical trial update on a phase 1/2 study evaluating retifanlimab with or without difluoromethylornithine for progressive high-grade glioma…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the combination of ipilimumab and nivolumab in patients with recurrent gliom…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma [Phase 1]
A Phase 1 clinical trial update assessing Telaglenastat in combination with radiation therapy and temozolomide for IDH-mutant diffuse astroc…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma [Phase 2]
Clinical trial update for a Phase 2 study evaluating GI-102 alone or with pembrolizumab before surgery in patients with recurrent or progres…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy [Phase 1]
Phase 1 trial evaluating allogeneic adipose-derived mesenchymal stem cells for recurrent glioblastoma or recurrent astrocytoma in patients u…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance) [Phase 3]
Phase 3 trial SIGMA is investigating safusidenib as maintenance therapy for IDH1-mutant glioma and related astrocytoma/oligodendroglioma sub…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy [Phase 4]
A Phase 4 clinical trial sponsored by Mayo Clinic comparing telehealth and in-person assessments in glioma patients undergoing oral chemothe…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer [Phase 3]
A Phase 3 trial is planned to evaluate adding vorasidenib to temozolomide after radiation in patients with IDH-mutant, Grade 3 astrocytoma; …
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: A Multicentre, Retrospective-prospective Real-world Study: to Evaluate the Effectiveness and Safety of Vorasidenib in Patients With Isocitrate Dehydrogenase IDH1/2 Mutant Grade 2 Astrocytoma or Oligodendroglioma (VICTORIA Study)
This document describes a multicenter real-world study protocol to evaluate the effectiveness and safety of vorasidenib in patients with IDH…
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CLINICAL_TRIALS research · 2024-10-02Clinical Trial Update: Extensive Resection of Malignant Brain Tumors Using Advanced Imaging Techniques [NA]
The study evaluates extensive surgical resection of malignant brain tumors using advanced imaging techniques and is currently recruiting.