Articular Cartilage Defect
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle [NA]
This completed trial compares a collagen-based modified microfracture technique to standard microfracture for ankle articular cartilage defe…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems [Phase 4]
A Phase 4 pilot trial aims to characterize platelet-rich plasma prepared by two different systems for knee osteoarthritis and cartilage dama…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee [NA]
This update describes a clinical trial comparing two methods for treating large chondral and osteochondral defects of the knee, currently no…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Introduction of ACI for Cartilage Repair [NA]
Clinical trial update introduces Autologous Chondrocyte Implantation (ACI) for cartilage repair, with recruitment ongoing for articular cart…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: The Biomechanical Outcomes of Autologous Chondrocyte Implantation
This study evaluates the biomechanical outcomes of autologous chondrocyte implantation for articular cartilage defects. It is currently recr…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: NOVOCART 3D Treatment Following Microfracture Failure [Phase 3]
This update indicates that Aesculap Biologics' NOVOCART 3D is in a Phase 3 trial for articular cartilage defects after microfracture failure…
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CLINICAL_TRIALS trial_result · 2023-08-28Clinical Trial Update: Phase 2 Clinical Trial of CartiLife® in the United States [Phase 2]
Phase 2 clinical trial update for CartiLife in the United States; current status is unknown for articular cartilage defect and degeneration.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Human Umbilical Cord Mesenchymal Stem Cell Transplantation in Articular Cartilage Defect [Phase 1]
Phase 1 trial evaluating transplantation of human umbilical cord mesenchymal stem cells for articular cartilage defects and osteoarthritis; …
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Follow-Up Study of CARTISTEM® Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect [Phase 3]
A completed Phase 3 trial comparing CARTISTEM to microfracture for knee articular cartilage injury/defect.
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Protected Versus Early Weight Bearing Post Microfracture Surgery [NA]
This clinical trial update compares protected versus early weight bearing after microfracture surgery for articular cartilage defects. The s…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: DeNovo NT Natural Tissue Graft Stratified Knee Study [NA]
Clinical trial update for DeNovo NT Natural Tissue Graft in knee cartilage defect patients; current status not specified.
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: DeNovo NT Ankle LDC Study
Clinical trial update for the DeNovo NT Ankle LDC study by Zimmer Orthobiologics; conditions include osteochondral lesions of the talus and …
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Cartilage Autograft Implantation System (CAIS) for the Repair of Knee Cartilage Through Cartilage Regeneration [NA]
The clinical trial NCT00881023 evaluating the Cartilage Autograft Implantation System (CAIS) for repairing knee articular cartilage defects …
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CLINICAL_TRIALS research · 2015-10-15Clinical Trial Update: Mesenchymal Stem Cells in a Clinical Trial to Heal Articular Cartilage Defects [Phase 1]
Phase 1 clinical trial investigating mesenchymal stem cells to heal articular cartilage defects; current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Comparison of Efficacy and Safety of Microfracture and Modified Microfracture [Phase 4]
Phase 4 trial update comparing efficacy and safety of Microfracture and Modified Microfracture for articular cartilage defects and osteoarth…
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CLINICAL_TRIALS trial_result · 2015-01-27Clinical Trial Update: Results at 10 to 14 Years After Microfracture in the Knee
Long-term results (10–14 years) from knee microfracture for articular cartilage defects.
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CLINICAL_TRIALS research · 2013-11-14Clinical Trial Update: A Study to Compare Two Techniques for Articular Cartilage Repair:ACIC Vs. MCIC [NA]
A clinical trial comparing two articular cartilage repair techniques (ACIC vs MCIC) in patients with articular cartilage defects. The curren…
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CLINICAL_TRIALS trial_result · 2012-08-21Clinical Trial Update: A Study to Evaluate the Safety of Augment™ Bone Graft [NA]
The report notes completion of a clinical trial evaluating the safety of Augment Bone Graft for articular cartilage defects.
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CLINICAL_TRIALS research · 2009-05-01Clinical Trial Update: The Use of Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Articular Cartilage Defects [Phase 2, Phase 3]
Update on a trial using autologous bone marrow mesenchymal stem cells to treat articular cartilage defects. The study is listed as Phase 2 a…