Arterial Occlusive Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD [NA]
This clinical trial update notes the completion of a study examining the role of microRNA-210 in regulating oxidative stress in patients wit…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation [Phase 1]
Phase 1 clinical and histological analysis of mesenchymal stem cells in amputation due to ischemia and peripheral arterial disease, with the…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Posterior Circulation Clot Burden Score (Pc-CBS) Predicts Clinical Outcome After Acute Ischemic Stroke Related to Posterior Circulation Occlusions : An Externally Validated Radiological Score
The study updates a completed trial evaluating the Posterior Circulation Clot Burden Score (Pc-CBS) and its external validation as a radiolo…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Follow-up Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-L)
A follow-up gene therapy trial for critical limb ischemia is currently enrolling by invitation, sponsored by Beijing Northland Biotech Co., …
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Sarpogrelate SR in Patients With Chronic Artery Occlusive Disease [Phase 4]
Phase 4 trial assessing the efficacy and safety of Sarpogrelate SR in chronic arterial occlusive disease and intermittent claudication has b…
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CLINICAL_TRIALS trial_result · 2022-07-29Clinical Trial Update: Sildenafil Efficacy Study on Time Walk From Peripheral Arterial Desease Patients (Stade II) With Arterial Claudication [Phase 3]
Phase 3 clinical trial evaluating sildenafil efficacy for time to walk in patients with peripheral arterial occlusive disease and arterial c…
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CLINICAL_TRIALS withdrawal · 2020-12-02Clinical Trial Update: Postoperative Hyperbaric Oxygen Treatments to Reduce Complications in Diabetic Patients Undergoing Vascular Surgery [Phase 2, Phase 3]
Clinical trial evaluating postoperative hyperbaric oxygen to reduce complications in diabetic patients undergoing vascular surgery was withd…
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease [NA]
Clinical trial update for the BARD LIFESTREAM balloon expandable covered stent in iliac arterial occlusive disease; completed with results p…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia [Phase 2]
Phase 2 safety and efficacy study of a gene therapy for critical limb ischemia has completed.
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CLINICAL_TRIALS withdrawal · 2019-06-13Clinical Trial Update: ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion [Phase 4]
A Phase 4 trial titled 'ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion' was withdrawn.
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Angio-Seal Evolution Device Registry
Completed registry study evaluating the Angio-Seal Evolution vascular closure device sponsored by Abbott Medical Devices. The registry cover…
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CLINICAL_TRIALS trial_result · 2017-07-14Clinical Trial Update: Edwards Lifesciences Self-Expanding Stent Peripheral Vascular Disease Study [NA]
Completed clinical trial evaluating Edwards Lifesciences’ self-expanding peripheral vascular stent for arterial disease; sponsor listed as C…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: The COPPER-B Trial [NA]
The COPPER-B trial has completed enrollment/status, but this update provides no results.
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion [Phase 1]
A Phase 1 dose-escalation and safety study of human plasmin in acute lower-extremity arterial occlusion due to native arteries or bypass gra…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Blood Factors and Peripheral Arterial Disease Outcomes
An NHLBI-sponsored clinical trial evaluating blood factors and outcomes in peripheral arterial disease has completed. The document notes the…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Mechanisms of Disability in Peripheral Arterial Disease
This clinical trial update indicates that the study on mechanisms of disability in Peripheral Arterial Disease has completed.
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Imaging of Plaque With Magnetic Resonance Imaging (MRI) [NA]
An update on a trial evaluating magnetic resonance imaging to image arterial plaque in arterial occlusive disease, with the study status lis…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease [Phase 1]
A Phase 1 safety study of adult stem cell therapy for severe leg artery disease has been terminated.
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CLINICAL_TRIALS withdrawal · 2014-10-15Clinical Trial Update: Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients [Phase 4]
A Phase 4 clinical trial investigating adenosine-induced myocardial blood flow in patients with peripheral artery disease was withdrawn.
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Cholesterol-Lowering Atherosclerosis Study (CLAS) [Phase 3]
Phase 3 Cholesterol-Lowering Atherosclerosis Study (CLAS) has completed the trial, per the update; the snippet provides status but no effica…
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CLINICAL_TRIALS trial_result · 2012-03-09Clinical Trial Update: Feasability Study of Autologous Bone Marrow Aspirate Concentrate for Treatment of CLI [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 feasibility study evaluating autologous bone marrow aspirate concentrate for treatment of …
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CLINICAL_TRIALS trial_result · 2011-08-19Clinical Trial Update: Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers [Phase 2]
Phase 2 trial evaluating hepatocyte growth factor via plasmid vector to improve perfusion in critical limb ischemia with peripheral ischemic…
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CLINICAL_TRIALS trial_result · 2010-03-31Clinical Trial Update: SIMPADICO - Study of Immune Modulation Therapy in Peripheral Arterial Disease and Intermittent Claudication Outcomes [Phase 3]
Phase 3 trial SIMPADICO investigating immune modulation therapy in peripheral arterial disease and intermittent claudication was terminated.
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CLINICAL_TRIALS trial_result · 2008-11-26Clinical Trial Update: A Clinical Study of Gadoteric Acid in Non-Coronary Magnetic Resonance (MR) Angiography [Phase 4]
Phase 4 clinical trial of Dotarem (gadoterate meglumine) for non-coronary MR angiography has completed, sponsored by Guerbet.
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CLINICAL_TRIALS trial_result · 2008-01-15Clinical Trial Update: Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery [Phase 3]
A Phase 3 trial evaluating Alfimeprase to dissolve leg blood clots and possibly avoid surgery was terminated.