Arrhythmogenic Right Ventricular Cardiomyopathy
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: IC14 (Atibuclimab) in Arrhythmogenic Cardiomyopathy [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating IC14 (Atibuclimab) in arrhythmogenic cardiomyopathy.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Arrhythmogenic Activity During Exercise in ARVC Patients [NA]
This clinical trial update notes a study on arrhythmic activity during exercise in patients with Arrhythmogenic Right Ventricular Cardiomyop…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Catheter Ablation Versus Anti-arrhythmic Drugs for Ventricular Tachycardia [NA]
Clinical trial update comparing catheter ablation to anti-arrhythmic drugs for ventricular tachycardia is active but not recruiting, involvi…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy [Phase 2]
A Phase 2 clinical trial is evaluating a glycogen synthase kinase-3 inhibitor as a targeted therapy for arrhythmogenic cardiomyopathy, curre…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Application of T1 Mapping in Real-World
A real-world study evaluating the use of T1 mapping in patients with myocardial infarction, hypertrophic cardiomyopathy, dilated cardiomyopa…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry
A multicenter registry in Brazil's public health system aims to improve care for hereditary cardiovascular diseases by enrolling patients ac…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia [NA]
A completed study evaluating DNA analysis from isolated cardiomyocytes for molecular diagnosis of arrhythmogenic right ventricular cardiomyo…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Gene Therapy for ACM Due to a PKP2 Pathogenic Variant [Phase 1, Phase 2]
A Phase 1/Phase 2 gene therapy trial for arrhythmogenic cardiomyopathy caused by PKP2 pathogenic variants is currently active but not recrui…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
Enrollment by invitation continues for a long-term follow-up study of an investigational gene therapy targeting PKP2-related arrhythmogenic …
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
A University of Edinburgh-led clinical trial update describing a recruiting study that uses cardiac imaging to evaluate myocardial fibrosis …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Pediatric Cardiomyopathy Mutation Analysis
A pediatric study at Indiana University is recruiting to analyze genetic mutations associated with various forms of cardiomyopathy.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM
The document summarizes a recruiting real-world observational study to characterize patient characteristics and the clinical course of sympt…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations [NA]
Completed clinical trial assessing health-related quality of life and physical activity in children with cardiac malformations, sponsored by…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Mayo AVC Registry and Biobank
This entry describes Mayo Clinic's AVC Registry and Biobank (NCT03049254), an ongoing registry and biobank focused on arrhythmogenic right v…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Distribution of Cell-cell Junction Proteins in Arrhythmic Disorders
This update reports results from a study on the distribution of cell-cell junction proteins in arrhythmic disorders, focusing on arrhythmoge…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Cardiovascular Multimodality Imaging Study
Montefiore Medical Center is conducting a cardiovascular multimodality imaging study that is currently recruiting participants. The study co…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC [Phase 1]
Open-label Phase 1 dose-escalation study to assess safety and preliminary efficacy of TN-401 in adults with PKP2 mutation-associated Arrhyth…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA
A clinical trial update describes an AI-enabled screening and diagnosis approach for cardiomyopathies using Coronary CT angiography, evaluat…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
An observational, non-interventional study sponsored by Tenaya Therapeutics to assess pre-existing antibodies against AAV9 and disease progr…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Local Inflammation in Arrhythmogenic Right Ventricular Cardiomyopathy [NA]
A clinical trial investigating local inflammation in patients with arrhythmogenic right ventricular cardiomyopathy is currently recruiting a…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Pilot Randomized Trial With Flecainide in ARVC Patients [Phase 2]
A Phase 2 pilot randomized trial evaluated flecainide in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC); the study is …
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: Risk Stratification in Children and Adolescents With Primary Cardiomyopathy
The update describes risk stratification efforts in pediatric patients with primary cardiomyopathy, including multiple cardiomyopathy subtyp…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
A clinical trial in China is exploring an integrative 'omics' approach to diagnose and prognosticate various forms of cardiomyopathy, includ…
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Metabolomic Study of All-age Cardiomyopathy
An update on an ongoing metabolomic study investigating molecular profiles across multiple cardiomyopathy types, including dilated and hyper…
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CLINICAL_TRIALS research · 2016-03-25Clinical Trial Update: German Centre for Cardiovascular Research Cardiomyopathy Register
The document reports an update to the German Centre for Cardiovascular Research Cardiomyopathy Register, a clinical trial registry tracking …