Appendiceal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies [Phase 1]
This is a Phase 1 clinical trial evaluating individual responses to hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcino…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating JAB-21822 in combination with cetuximab for KRAS G12C-mutant advanced colorectal cancer and other soli…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis [NA]
This clinical trial update describes a feasibility study to guide personalized hyperthermic intraperitoneal chemotherapy (HIPEC) for high-gr…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer [Phase 1]
Clinical trial update indicating a Phase 1 study of PIPAC (pressurized intraperitoneal aerosol chemotherapy) to treat peritoneal carcinomato…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial [Phase 3]
A Phase 3 study of pressurized intraperitoneal aerosolized chemotherapy with mitomycin for unresectable appendiceal or colorectal cancer wit…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis
This clinical trial update reports on a study evaluating plasma 5hmC DNA signatures as biomarkers for metastasis in colorectal and appendice…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei [NA]
A crossover trial of systemic chemotherapy for metastatic well-differentiated mucinous appendiceal adenocarcinoma with pseudomyxoma peritone…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer [NA]
This clinical trial update describes an individualized dose-escalation approach using 5-fluorouracil for gastrointestinal cancers and is cur…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Biweekly Intraperitoneal Oxaliplatin With Systemic Capecitabine and Bevacizumab for Patients With Peritoneal Carcinomatosis From Appendiceal or Colorectal Cancer [Phase 1]
Phase 1 clinical trial evaluating biweekly intraperitoneal oxaliplatin with systemic capecitabine and bevacizumab for peritoneal carcinomato…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™) [Phase 4]
Phase 4 study evaluating intraoperative imaging of gastrointestinal cancers using pafolacianine (CYTALUX); recruitment is ongoing. The spons…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers [Phase 1]
Phase 1 clinical trial update evaluating the NALIRIFOX regimen (nal-IRI plus 5-FU/LV plus oxaliplatin) as first-line therapy for advanced sm…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer [Phase 1]
Phase 1 trial evaluating intraperitoneal aerosolized nanoliposomal irinotecan (Nal-IRI) for peritoneal carcinomatosis from gastrointestinal …
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer. [NA]
This is a prospective study (EQUITY GI) to improve quality, inclusivity, and trial participation for Black patients with gastrointestinal ca…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Genetics of Appendix Cancer Study
A clinical trial is currently recruiting to investigate the genetics of appendiceal cancers.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms [NA]
Clinical trial update evaluating the diagnostic value of diffusion-weighted MRI for high-risk colorectal and appendiceal neoplasms; the stud…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer [Phase 2]
Phase 2 clinical trial evaluating Taxol (paclitaxel) given intravenously and intraperitoneally with Tasigna (nilotinib) taken orally for per…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) [NA]
The LIVELONG trial from University of California, Davis is an ongoing study evaluating locally ablative therapy for oligoprogressive gastroi…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Molecular Characterisation of Appendiceal Cancer
A clinical trial focusing on molecular characterization of appendiceal cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: HIPEC for Peritoneal Carcinomatosis [Phase 2]
This update reports results from a Phase 2 clinical trial evaluating hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcin…
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CLINICAL_TRIALS withdrawal · 2024-08-20Clinical Trial Update: Intraperitoneal LSTA1 in CRS-HIPEC [Phase 1]
The document reports the withdrawal of a Phase 1 trial of intraperitoneal LSTA1 for peritoneal cancers. The conditions include colorectal ca…
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: Value of Right-sided Hemicolectomy for Chldren With High-risk Neuroendocrine Tumors of the Appendix
A pediatric surgical trial evaluating the value of right-sided hemicolectomy for high-risk appendiceal neuroendocrine tumors; the study is c…
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis [Phase 2]
Phase 2 trial comparing CRS-HIPEC using mitomycin-C vs. melphalan for colorectal peritoneal carcinomatosis (appendiceal/colorectal cancers).
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies [Phase 1, Phase 2]
Phase 1/2 trial evaluating ONCOS-102 in combination with durvalumab in advanced peritoneal malignancies (colorectal, ovarian, and appendicea…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix [Phase 2]
Phase 2 trial evaluating surgery with either oxaliplatin or mitomycin C for appendiceal tumors and primary peritoneal cancer; the study comp…
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer [Phase 1]
Phase 1 trial evaluating the combination of oxaliplatin and capecitabine in patients with colorectal cancer, appendiceal cancer, or small in…