Aplastic Anemia
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia [Phase 1]
Phase 1 trial evaluating allogeneic stem cell transplantation for severe aplastic anemia; the study status is completed.
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow Transplant [Phase 2]
Phase 2 study evaluating a conditioning regimen of cyclophosphamide and anti-thymocyte globulin followed by methotrexate and cyclosporine to…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Treatment [Phase 2]
Phase 2 trial evaluating horse T-cell leukemia/lymphoma ATG and cyclosporine in patients with aplastic anemia unresponsive to or suboptimall…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders [Phase 1, Phase 2]
A completed Phase 1/2 study from Singapore General Hospital evaluated a Traditional Chinese Medicine formulation for supportive management o…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: ATG Combined With Cyclophosphamide And Cord Blood Transfusion in Treating Patients With Severe Aplastic Anemia [Phase 4]
This entry provides a Phase 4 clinical trial update evaluating ATG-based therapy with cyclophosphamide and cord blood transfusion for severe…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Bone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia [Phase 2]
Phase 2 bone marrow transplant trial for patients with refractory severe aplastic anemia was terminated.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301) [Phase 1, Phase 2]
A phase 1/2 trial evaluating fludarabine-based conditioning for severe aplastic anemia has completed recruitment with results posted.
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: High-Tc Susceptometer to Monitor Transfusional Iron Overload
Clinical trial update reporting that the study evaluating a High-Tc Susceptometer to monitor transfusional iron overload has completed, in p…
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CLINICAL_TRIALS trial_result · 2016-08-05Clinical Trial Update: Efficacy and Safety of Thrombopoietin In Patients With Severe and Very Severe Aplastic Anemia [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of thrombopoietin in patients with severe and very severe aplastic anemia.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: A Phase II Study of Umbilical Cord Blood Transplantation [Phase 2]
A Phase II study of Umbilical Cord Blood Transplantation was terminated, with results posted in 2016 for diseases including leukemia, lympho…
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders [Phase 2]
A Phase 2 trial testing nonmyeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors for multiple hematologic dis…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Extended Platelet Parameters as a Means to Differentiate Immune Thrombocytopenia From Hypo-proliferative Thrombocytopenias.
This completed clinical trial from Beth Israel Medical Center evaluated whether extended platelet parameters can distinguish immune thromboc…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Drug Etiology of Aplastic Anemia and Related Dyscrasias
NHLBI-sponsored clinical trial evaluating etiologies of aplastic anemia and related dyscrasias has completed.
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Cord Blood Stem Cell Transplantation Study (COBLT) [Phase 2]
Phase 2 COBLT cord blood stem cell transplantation trial sponsored by NHLBI has completed, studying transplantation for aplastic anemia, Fan…
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors [Phase 2]
Phase 2 results from a trial of peripheral blood stem cell transplantation using haploidentical related donors were completed, led by the Un…
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia [Phase 2]
Phase 2 trial comparing Rabbit Antithymocyte Globulin to Campath-1H for severe aplastic anemia; study completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia [Phase 1, Phase 2]
A pilot study evaluating fludarabine plus cyclophosphamide in refractory severe aplastic anemia completed phases 1 and 2 with results posted…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Aplastic Anemia Epidemiology: Incidence and Case-control
This ClinicalTrials.gov entry reports a completed epidemiological study on aplastic anemia, focusing on its incidence and a case-control ana…
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic Anemia [Phase 2]
Phase 2 clinical trial update evaluating T-cell-depleted bone marrow and G-CSF-stimulated peripheral stem cell transplantation from related …
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CLINICAL_TRIALS trial_result · 2015-11-11Clinical Trial Update: Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cyclophosphamide plus cyclosporine in treatment-naive severe aplastic anemia; the study status is comple…
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CLINICAL_TRIALS trial_result · 2015-05-14Clinical Trial Update: A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure [Phase 2]
Phase 2 trial evaluating daclizumab for bone marrow failure (aplastic anemia and related conditions) was terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia [Phase 1, Phase 2]
This clinical trial update discusses the safety and efficacy of autologous adipose-derived mesenchymal stem cells (AD-MSC) and autologous ad…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Safety and Efficacy of Desferasirox in Chinese Patients With Iron Overload and Aplastic Anemia [Phase 4]
Phase 4 study assessing the safety and efficacy of Desferasirox in Chinese patients with iron overload and aplastic anemia.
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CLINICAL_TRIALS trial_result · 2014-09-11Clinical Trial Update: Investigation of the Cylex® ImmuKnow® Assay
A completed clinical trial investigating the Cylex ImmuKnow immune function assay across several hematologic diseases.
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia [Phase 2]
Phase 2 trial update for rituximab in treating moderate aplastic anemia, pure red cell aplasia, or Diamond-Blackfan anemia with completed st…