Aplastic Anemia
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CLINICAL_TRIALS trial_result · 2020-04-02Clinical Trial Update: King's Invasive Aspergillosis Study II [Phase 4]
A Phase 4 clinical trial update for King's Invasive Aspergillosis Study II (NCT02875743) from King's College Hospital NHS Trust, with condit…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/Disorders [Phase 2]
Phase 2 trial update of an allogeneic hematopoietic cell transplant in hematologic cancers/disorders; status completed with results posted i…
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CLINICAL_TRIALS trial_result · 2019-08-16Clinical Trial Update: Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia Patients [Phase 4]
Phase 4 trial update on safety and efficacy of Exjade for transfusion-dependent iron overload in patients with aplastic anemia; study termin…
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Alemtuzumab to Treat Severe Aplastic Anemia [Phase 2]
Phase 2 trial evaluating alemtuzumab for severe aplastic anemia (refractory/relapse) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A in Naive Aplastic Anemia (AA) Subjects [Phase 2]
Phase 2 trial evaluating eltrombopag in combination with rabbit anti-thymocyte globulin and cyclosporine A in naive aplastic anemia patients…
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CLINICAL_TRIALS trial_result · 2019-05-03Clinical Trial Update: A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic Anemia [Phase 2]
Phase 2 trial assessing safety and efficacy of eltrombopag in Japanese patients with refractory, moderate or more severe aplastic anemia (co…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Eltrombopag for Moderate Aplastic Anemia [Phase 2]
This document summarizes Phase 2 results from a trial of eltrombopag in moderate aplastic anemia, with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: Study of High Dose Cyclophosphamide in Patients With Severe Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria [Phase 2]
A Phase 2 study evaluated high-dose cyclophosphamide in patients with severe aplastic anemia and paroxysmal nocturnal hemoglobinuria. The tr…
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: Extended Dosing With Eltrombopag for Severe Aplastic Anemia [Phase 2]
Phase 2 trial update on extended dosing of eltrombopag for severe aplastic anemia completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients [Phase 2, Phase 3]
Clinical trial update for peripheral blood allogenic stem cell transplantation using non-anti thymocyte globulin regimens in severe aplastic…
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients [Phase 2]
Phase 2 pilot study of eltrombopag in refractory aplastic anemia completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: Danazol for Genetic Bone Marrow and Lung Disorders [Phase 1, Phase 2]
Phase 1/2 trial update for danazol in aplastic anemia and related bone marrow/lung disorders; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine [Phase 2]
Phase 2 trial evaluating hematopoietic stem cell transplantation after a chemotherapy-only cytoreduction with busulfan, cyclophosphamide, an…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease
A NICHD-sponsored clinical trial on fertility preservation for women undergoing gonadotoxic therapy or hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Phase III Randomized Study of Cyclophosphamide With or Without Antithymocyte Globulin Before Bone Marrow Transplantation in Patients With Aplastic Anemia [Phase 3]
Phase III randomized trial comparing cyclophosphamide with or without antithymocyte globulin before bone marrow transplantation in patients …
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Efficacy and Safety of Eltrombopag In Patients With Severe and Very Severe Aplastic Anemia [Phase 2]
Phase 2 trial evaluating eltrombopag for severe, very severe, and moderate aplastic anemia reports efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias [Phase 2]
Phase 2 study of deferasirox for iron overload in beta-thalassemia patients who cannot be treated with deferoxamine, as well as related chro…
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia
A multi-center case-control study investigating multiple risk factors for aplastic anemia has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Neuropsychological Effects of Immunosuppressive Treatment in Subjects With Aplastic Anemia
This clinical trial update reports on the neuropsychological effects of immunosuppressive treatment in subjects with aplastic anemia; the st…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells [Phase 1]
A Phase 1 trial of unrelated umbilical cord blood transplantation augmented with ALDHbr cord blood cells has completed, with the update desc…
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CLINICAL_TRIALS trial_result · 2017-06-15Clinical Trial Update: Cord Blood Transplantation in Severe Aplastic Anemia [Phase 2]
Phase 2 clinical trial evaluating cord blood transplantation for severe aplastic anemia has completed, including patients with hereditary di…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies [NA]
Clinical trial update for fludarabine-based conditioning prior to allogeneic transplantation in advanced hematologic malignancies; study com…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia [Phase 2]
Phase 2 trial comparing three immunosuppressive regimens for severe aplastic anemia; results of the study have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA [Phase 2, Phase 3]
Completed Phase 2 and Phase 3 clinical trial evaluating stem cell transplant for Dyskeratosis Congenita and Aplastic Anemia; results posted …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL) [Phase 2]
A phase 2 trial of alemtuzumab in myelodysplastic syndrome, aplastic anemia, and T-cell large granular lymphocytic leukemia was terminated, …