Aplastic Anemia
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Study on the Short-term Efficacy and Safety of Recombinant Human Thrombopoietin Combined With Immunosuppressant Sequential Eltrombopag Ethanolamine Dry Suspension in the Treatment of SAA/TD-NSAA [Phase 3]
Phase 3 clinical trial evaluating short-term efficacy and safety of combining recombinant human thrombopoietin with sequential eltrombopag e…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Real-world Outcomes of Aplastic Anemia Patients Treated With Eltrombopag: A Medical Claims Database Study
This study analyzes real-world outcomes of aplastic anemia patients treated with eltrombopag using a medical claims database.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Treatment of Transfusion-dependent Nonsevere Aplastic Anemia With Luspatercept: a Multicenter Prospective Clinical Study [NA]
A multicenter prospective trial evaluating luspatercept for transfusion-dependent non-severe aplastic anemia is currently not recruiting.
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Reduced-dose Conditioning Regimen Containing TBI in HSCT Treating Elderly Patients With Aplastic Anemia [Phase 2]
Phase 2 trial assessing a reduced-dose conditioning regimen that includes total body irradiation (TBI) for hematopoietic stem cell transplan…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Standard Immunosuppressive Therapy Combined With Romiplostim N01 as First-line Treatment for Severe Aplastic Anemia [Phase 2]
A phase 2 clinical trial investigates using standard immunosuppressive therapy with Romiplostim as a first-line treatment for severe aplasti…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia [Phase 2]
A Phase 2 clinical trial is evaluating a reduced-dose cyclophosphamide regimen combined with standard immunosuppressive therapy for severe a…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years [Phase 2]
This Phase 2 clinical trial update discusses using hematopoietic stem cell transplantation for patients with refractory or relapsed aplastic…
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia [EARLY_Phase 1]
Early-phase 1 clinical trial update announcing recruitment for CD7 CAR-T cells as a bridge to allogeneic stem cell transplantation in severe…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: REscuing Bone Marrow Function in Patients with AplaStic AnaEmia and Bone Marrow FaiLure Post AllogEneiC Transplantation 2 [Phase 1, Phase 2]
A Phase 1/2 clinical trial in Melbourne Health is investigating rescue of bone marrow function in patients with aplastic anemia and bone mar…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation [NA]
This ClinicalTrials.gov update reports a completed feasibility study evaluating an adapted physical activity program for children, adolescen…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: A Study of Romiplostim for the Treatment of Refractory Transfusion-dependent NSAA [Phase 4]
Phase 4 clinical trial evaluating romiplostim for refractory transfusion-dependent aplastic anemia; currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: NAC for Hematopoietic Recovery in SAA [Phase 2]
Phase 2 clinical trial evaluating N-acetylcysteine for hematopoietic recovery in aplastic anemia; sponsored by Peking University People's Ho…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Ropustin for Refractory Aplastic Anaemia After Radiotherapy - a Single-centre, Prospective, Open-label, Single-arm Study [Phase 4]
A Phase 4, single-centre, open-label, single-arm trial evaluating Ropustin for refractory aplastic anemia after radiotherapy; currently not …
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag [Phase 4]
This is a Phase 4 prospective study evaluating lusutrombopag for aplastic anemia, with status NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2024-05-22Clinical Trial Update: Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA [Phase 4]
This clinical trial update describes a Phase 4 study comparing luspatercept plus cyclosporine vs cyclosporine alone for newly diagnosed non-…
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CLINICAL_TRIALS research · 2017-07-26Clinical Trial Update: Clinical Study of Non Severe Aplastic Anemia Treated With Cyclosporine, Androgen and Levamisole [NA]
A clinical study is evaluating cyclosporine, an androgen, and levamisole for non-severe aplastic anemia, with the current status listed as U…
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CLINICAL_TRIALS research · 2017-04-07Clinical Trial Update: Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Aplastic Anemia [Phase 1]
Phase 1 clinical trial evaluating umbilical cord-derived mesenchymal stem cell therapy for aplastic anemia, sponsored by Hebei Medical Unive…
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CLINICAL_TRIALS research · 2016-07-14Clinical Trial Update: Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
This clinical trial update outlines the use of MRI monitoring in patients with aplastic anemia and low- to intermediate-1-risk myelodysplast…
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CLINICAL_TRIALS research · 2016-05-13Clinical Trial Update: Etiology of Blood Dyscrasias: Analysis of the International Agranulocytosis and Aplastic Anemia Study Data
This trial update analyzes data from the International Agranulocytosis and Aplastic Anemia Study to explore the etiology of blood dyscrasias…
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CLINICAL_TRIALS research · 2016-04-05Clinical Trial Update: Comparison of Two Different Doses of Rabbit ATG-Fresenius With Cyclosporin in the Treatment of Acquired Aplastic Anaemia [NA]
A clinical trial update evaluating two different doses of rabbit ATG-Fresenius with cyclosporin for acquired aplastic anemia.
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CLINICAL_TRIALS research · 2014-10-08Clinical Trial Update: Safety Study of CD3/CD19 Depleted Haploidentical Stem Cells [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating CD3/CD19 depleted haploidentical stem cell transplants in pediatric patients with acute leukemia, aplast…
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CLINICAL_TRIALS research · 2014-09-25Clinical Trial Update: Mesenchymal Stem Cells Co-transplantation in Alternative Donor Transplantation of Severe Aplastic Anemia. [Phase 2]
Phase 2 clinical trial evaluating co-transplantation of mesenchymal stem cells in alternative donor transplantation for severe aplastic anem…
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CLINICAL_TRIALS research · 2014-08-20Clinical Trial Update: Pharmacokinetic Study of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 pharmacokinetic study of fludarabine in pediatric patients undergoing hematopoietic stem cell transplantation, sponsored by Seoul Na…
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CLINICAL_TRIALS research · 2014-08-18Clinical Trial Update: Treatment Protocol of Child SAA With the Injection of Mesenchymal Stem Cells（Umbilical Cord Derived） [Phase 4]
Phase 4 clinical trial protocol update evaluating infusion of umbilical cord-derived mesenchymal stem cells to treat children with severe ap…
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CLINICAL_TRIALS research · 2014-03-26Clinical Trial Update: Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial evaluating the safety and tolerability of donor-derived allogeneic B-cell concentrates to support immune…