Aortic Stenosis
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Cardiac Amyloidosis Prevalence and Outcome in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Implantation [NA]
This completed study evaluated the prevalence of cardiac amyloidosis in patients with aortic stenosis undergoing transcatheter aortic valve …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Safety & Efficacy of the J-Valve Ausper System in Patients With Severe Aortic Stenosis and/or Aortic Regurgitation [NA]
A completed clinical trial evaluated the safety and efficacy of the J-Valve Ausper System in patients with severe aortic stenosis and/or aor…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Interpectoral-pectoserratus Plane Block for Minimally Invasive Aortic Valve Replacement Via Right Anterior Minithoracotomy [Phase 4]
Phase 4 clinical trial update evaluating the analgesic effectiveness of the interpectoral-pectoserratus plane block for pain control during …
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis [EARLY_Phase 1]
An early-phase Phase 1 study evaluated the prevalence of transthyretin cardiac amyloidosis among patients with clinically significant aortic…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1:1) [Phase 4]
This Phase 4 trial update notes the completion of a study comparing anticoagulation alone versus anticoagulation plus aspirin following tran…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Portico Next Generation Approval Study [NA]
Clinical trial update for Abbott's Portico Next Generation Transcatheter Aortic Valve in symptomatic severe aortic stenosis; results were po…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Reversibility of Cardiac Conduction Disturbances Following TAVI [NA]
A clinical trial is evaluating whether cardiac conduction disturbances after transcatheter aortic valve implantation are reversible. The stu…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis
This trial update describes the feasibility, safety, and effectiveness evaluation of the ACURATE neo2 transcatheter heart valve for severe b…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Positron Emission Tomography / Magnetic Resonance Imaging in Aortic Stenosis
An update on a completed clinical trial evaluating the use of PET/MRI imaging in patients with Aortic stenosis and Transthyretin amyloidosis…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: PERIGON Pivotal Trial [NA]
Update on the PERIGON pivotal trial for aortic stenosis with results posted as of 2024-06-04; trial status is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic Stenosis [NA]
This clinical trial update notes the completion of a feasibility study evaluating transcatheter aortic valve replacement (TAVR) in low-risk …
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Mechanism of Decompensation Evaluation - Aortic Stenosis
A completed University of Edinburgh clinical trial evaluating the mechanism of decompensation in aortic stenosis, with investigation into my…
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: PERIGON Japan Trial [NA]
Clinical trial update for the PERIGON Japan trial has completed; results were posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure [Phase 4]
Phase 4 trial evaluating the effects of levosimendan on cardiac function after transcatheter aortic valve replacement in patients with heart…
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR). [Phase 4]
Phase 4 clinical trial examining glucocorticoid treatment in transcatheter aortic valve replacement (TAVR) to reduce conduction disturbances…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 clinical trial comparing procedural sedation using propofol versus dexmedetomidine during transcatheter aortic valve implantation ha…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve Replacement
Clinical trial assessing how the type of anesthesia influences outcomes in transfemoral aortic valve replacement for aortic stenosis has com…
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Replacement [NA]
Trial update for a transcaval closure device used in transcaval access ports during transcatheter aortic valve replacement; study status ter…
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CLINICAL_TRIALS trial_result · 2023-01-05Clinical Trial Update: A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis [NA]
Clinical trial update on using fractional flow reserve to assess intermediate coronary stenoses in patients with severe aortic stenosis; the…
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation [Phase 3]
Phase 3 trial comparing anticoagulation versus acetylsalicylic acid after transcatheter aortic valve implantation is currently recruiting.
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CLINICAL_TRIALS trial_result · 2022-10-27Clinical Trial Update: IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVI [Phase 4]
Phase 4 trial update for IV sodium ferric gluconate complex in patients undergoing transcatheter aortic valve implantation (TAVI).
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CLINICAL_TRIALS trial_result · 2022-09-15Clinical Trial Update: Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease [Phase 4]
Phase 4 clinical trial evaluating the effect of blood pressure control on improvement of left ventricular hypertrophy in hypertension patien…
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement [NA]
A terminated clinical trial comparing Perceval sutureless aortic valve replacement with standard AVR; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: Inflammation and Thrombosis in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (TAVR) [Phase 4]
Phase 4 trial update on inflammation and thrombosis in patients with severe aortic stenosis after transcatheter aortic valve replacement (TA…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden [Phase 3]
Phase 3 trial evaluating antifibrotic therapy to induce regression of myocardial fibrosis after TAVI in patients with severe aortic stenosis…