Ankle Osteoarthritis
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CLINICAL_TRIALS trial_result · 2026-08-07Clinical Trial Results: Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects With Ankle Osteoarthritis [Phase 1, Phase 2]
Phase 1/2 trial evaluating intra-articular Axolotl Ambient versus saline in ankle osteoarthritis; study terminated with results posted.
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Effects of Graded Motor Imagery in Individuals With Foot/Ankle Osteoarthritis [NA]
A clinical trial is evaluating graded motor imagery as a treatment for ankle and foot osteoarthritis and is currently recruiting participant…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Pragmatic Clinical Trial [NA]
This is a completed pragmatic clinical trial funded by the Department of Defense evaluating ultrasound-guided percutaneous peripheral nerve …
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Comparison of Customized and Standard Total Ankle Prostheses [NA]
A clinical trial comparing customized and standard total ankle prostheses for ankle osteoarthritis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells
A clinical trial evaluating adipose-derived regenerative cells for treating osteoarthritis in multiple joints has been terminated.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Clinical and Radiological Evaluation of Total Ankle Replacement (ProtesiTT)
A clinical trial assessing the clinical and radiological outcomes of a total ankle replacement device (ProtesiTT) is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Evaluation of the Single Injection of BMAC vs HA in the Treatment of the Ankle Osteoarthritis [NA]
A clinical trial comparing a single injection of bone marrow aspirate concentrate (BMAC) to hyaluronic acid (HA) for ankle osteoarthritis ha…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles
The clinical trial evaluating detection, classification, and treatment of misaligned arthritic ankles in ankle osteoarthritis was terminated…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients [NA]
A completed clinical trial evaluated whether rocker bottom shoes and ankle-foot orthoses reduce pain and improve mobility in people with ank…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Validation of the Italian Version of the Forgotten Joint Score (FJS-12) in Total Ankle Replacement
The trial update reports validation of the Italian version of the Forgotten Joint Score (FJS-12) for patients undergoing total ankle replace…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Early MOtion Total Ankle Artroplasty [NA]
A clinical trial update for an early motion total ankle arthroplasty study, currently recruiting to treat ankle osteoarthritis and associate…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Post- Approval Hintermann Series H® Study 1
Post-approval study of the Hintermann Series H device for ankle osteoarthritis conditions is currently active and not recruiting.
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Orthotic Dose Response Study [NA]
A completed clinical trial evaluating the dose-response of foot orthotics for ankle osteoarthritis and pes planus (flat foot).
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Cryoneurolysis for Improvements in Pain, ADL and QOL in Patients With Ankle Osteoarthritis [NA]
Clinical trial update reports completed results for cryoneurolysis addressing pain, activities of daily living, and quality of life in patie…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Development of Stance Control Orthotic Knee Joint For Improvement of KAFO Users
Update on development of a stance-control orthotic knee joint to improve KAFO users; the trial is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2021-05-05Clinical Trial Update: Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement [NA]
A completed randomized clinical trial evaluating two- and three-piece total ankle replacement for ankle osteoarthritis; results posted.
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen
This clinical trial update compares three dosage regimens of tranexamic acid in major orthopedic surgery, focusing on knee osteoarthritis an…
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Gait Analysis Following Total Ankle Replacement and Subtalar Fusion
This clinical trial update reports gait analysis findings following total ankle replacement and subtalar fusion in patients with ankle osteo…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Safety and Effectiveness of Agilus (Hyaluronic Acid) for Ankle Osteoarthritis [NA]
A terminated clinical trial evaluating Agilus, hyaluronic acid, for ankle osteoarthritis has posted results assessing safety and effectivene…
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CLINICAL_TRIALS other · 2017-05-17Clinical Trial Update: Ankle Osteoarthritis
This is a clinical trial update for ankle osteoarthritis. The sponsor is Hospices Civils de Lyon and the study status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Post-Approval Study to Investigate the Long Term (8 Year) Survivorship of STAR Ankle Among Continued Access Study Patients
Post-approval study update examining the long-term eight-year survivorship of the STAR Ankle implant among continued access study patients.
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CLINICAL_TRIALS research · 2015-07-24Clinical Trial Update: Cross-cultural Adaptation and Validation of the Ankle Osteoarthritis Scale (AOS) for Use in French-speaking Populations
A cross-cultural adaptation and validation study of the Ankle Osteoarthritis Scale for French-speaking populations has completed.
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: Effects of Intraarticular Botulinum Toxin A in Ankle Osteoarthritis [NA]
Clinical trial update on the effects of intraarticular botulinum toxin A for ankle osteoarthritis, status completed.
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CLINICAL_TRIALS trial_result · 2009-06-11Clinical Trial Update: Efficacy of 3 Weekly Injections of Hyaluronate in Patients With Ankle Osteoarthritis [Phase 2]
Phase 2 trial results evaluate the efficacy of three weekly injections of sodium hyaluronate in patients with ankle osteoarthritis.