Anhedonia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-09Clinical Trial Results: Prevention of Anhedonia in Children [NA]
Clinical trial results on preventing anhedonia in children have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Results: A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure [Phase 3]
Phase 3 trial evaluating aticaprant plus antidepressant to prevent return of depressive symptoms in adults with Major Depressive Disorder an…
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Update: Pramipexole for Anhedonic Depression [Phase 3]
Phase 3 trial update for pramipexole in anhedonic depression has completed enrollment and status is completed.
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Update: Long-term Efficacy of Pramipexole in Anhedonic Depression [Phase 3]
Phase 3 trial assessing long-term efficacy of pramipexole in anhedonic depression has completed.
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Anhedonia, Development, and Emotions: Phenotyping and Therapeutics [Phase 4]
Phase 4 clinical trial update examining anhedonia, development, and emotions, including phenotyping and therapeutic approaches; results have…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Prevention of Anhedonia in Children [NA]
The document reports the completed status of a clinical trial focused on preventing anhedonia in children, related to depression.
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Individualized Neuromodulation for Anhedonic Depression [NA]
A clinical trial evaluating individualized neuromodulation for anhedonic depression has completed.
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy [Phase 3]
Phase 3 study of Aticaprant 10 mg as adjunctive therapy for adults with major depressive disorder and anhedonia has completed, with results …
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Investigating LIFUP in Anhedonic Depression [NA]
A UCLA-sponsored clinical trial evaluating low-intensity focused ultrasound (LIFUP) for anhedonic depression has completed.
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Sleep and Healthy Aging Research on Depression for Younger Women [Phase 1]
Phase 1 clinical trial update on sleep and healthy aging research addressing depression and anhedonia in younger women. Results have been po…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: DTA (Dopaminergic Therapy for Anhedonia) Study [Phase 4]
Phase 4 trial of Dopaminergic Therapy for Anhedonia has completed, with results posted on 2024-12-16.
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: TMS Alteration of the Reward Positivity [NA]
Completed clinical trial evaluating the effect of transcranial magnetic stimulation (TMS) on reward processing in individuals with anhedonia…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Text Based Digital Interventions Prompting Enjoyable and Healthy Behaviors [NA]
This completed clinical trial evaluated text-based digital interventions designed to promote enjoyable and healthy behaviors in people with …
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia [NA]
A completed clinical trial from the University of North Carolina investigated the causal role of prefrontal control in decision-making among…
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: REward Processing And Citalopram Study [Phase 1, Phase 2]
Phase 1 and Phase 2 trial update for a study investigating reward processing and citalopram in individuals with anhedonia.
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Serotonin-receptor Agonism in Reward Processing [Phase 2]
Phase 2 clinical trial evaluating serotonin-receptor agonism for anhedonia has completed.
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Translational Model of Anhedonia [NA]
Clinical trial update for a translational model of anhedonia; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine Treatment [Phase 4]
Phase 4 trial evaluating reward processing in major depressive disorder before and after desvenlafaxine treatment.
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Development of a Novel Transdiagnostic Intervention for Anhedonia - R61 Phase [NA]
A completed clinical trial investigating a novel transdiagnostic intervention for anhedonia; results were posted in 2020.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: The Effect of CBT- Based Weight Loss Program on Obesity [NA]
This document reports the completed status of a clinical trial evaluating a cognitive-behavioral therapy-based weight loss program for obesi…
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CLINICAL_TRIALS trial_result · 2016-08-17Clinical Trial Update: Kappa Opioid Receptor Imaging in Depression (KOR Depression)
A clinical trial investigating kappa opioid receptor imaging in major depressive disorder and anhedonia has been terminated.
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Dopamine Neurotransmission in Major Depression
A completed clinical trial update from McLean Hospital examining dopamine neurotransmission in Major Depressive Disorder and Anhedonia.