Anca-associated Vasculitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: An Exploratory Study of MT-2990 in Patients With AAV [Phase 1]
A completed Phase 1 exploratory study of MT-2990 in patients with ANCA-associated vasculitis (AAV).
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Comparison of ANCA and Anti-GBM Auto-antibodies Removal Kinetics Between Plasma Exchanges and Immunoadsorption in Patients With ANCA-associated Vasculitis or Anti-GBM Disease [NA]
A completed clinical trial comparing removal kinetics of ANCA and anti-GBM autoantibodies using plasma exchange versus immunoadsorption in p…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases [EARLY_Phase 1]
A Phase 1 targeted CD19 CAR-T therapy trial for autoimmune diseases has been suspended.
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: the Safety and Efficacy of Targeted BCMA In Vivo LV Injection for Recurrent or Refractory Autoimmune Diseases [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating the safety and efficacy of a targeted BCMA in vivo lentiviral vector injection for recurrent or r…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Biosimilars of Rituximab in ANCA-associated Vasculitis Compared to the Originator
A completed clinical trial comparing rituximab biosimilars to the originator in ANCA-associated vasculitis, including granulomatosis with po…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis [NA]
This entry reports the termination of a clinical trial evaluating maintenance therapy tailored to CD5+ regulatory B cell recovery in ANCA-as…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Innovative Anti-pneumococcal Vaccine Strategies in Patients With ANCA-associated Vasculitis Receiving Rituximab Therapy [Phase 2]
A Phase 2 trial update on innovative pneumococcal vaccine strategies for patients with ANCA-associated vasculitis receiving rituximab therap…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Comparison Between a Long Term and a Conventional Maintenance Treatment With Rituximab [Phase 3]
A Phase 3 trial comparing long-term versus conventional rituximab maintenance in ANCA-associated vasculitis has completed, with results repo…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides [Phase 3]
A Phase 3 multicenter, randomized, double-blind trial evaluated whether rosuvastatin affects subclinical markers of atherosclerosis in patie…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Efficacy and Safety of Substitution of Glucocorticoid for BDB-001 Injection in Patients With Anti-neutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis [Phase 1, Phase 2]
Phase 1/2 trials evaluating substitution of glucocorticoid for BDB-001 in ANCA-associated vasculitis have completed, with reported efficacy …
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases [Phase 2]
Phase 2 clinical trial update on BCMA-CD19 CAR-T therapy for refractory autoimmune diseases, currently recruiting. The study targets several…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Anti-CD 19 CAR-T Cell Therapy in Patients With ANCA Vasculitis [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating an anti-CD19 CAR-T cell therapy for ANCA-associated vasculitis, with recruitment not yet started.
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease [NA]
This clinical trial update reports a study of YTS109 cell injection for recurrent or refractory autoimmune diseases that is currently recrui…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: PR3-AAV Resilient Remission or PRRR [Phase 2]
A Phase 2 trial of PR3-AAV Resilient Remission (PRRR) for ANCA-associated vasculitis, including granulomatosis with polyangiitis and microsc…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Hydroxychloroquine in ANCA Vasculitis Evaluation [Phase 4]
Phase 4 trial update evaluating hydroxychloroquine for ANCA-associated vasculitis, including microscopic polyangiitis, eosinophilic granulom…
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis [Phase 3]
A Phase 3 clinical trial update exploring rituximab for durable remission in ANCA-associated vasculitis.
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CLINICAL_TRIALS trial_result · 2023-08-16Clinical Trial Update: Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis [Phase 2]
Phase 2 trial evaluating CCX168 for ANCA-associated vasculitis has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM) [Phase 4]
Phase 4 trial update evaluating efficacy and safety of telitacicept as maintenance treatment for ANCA-associated vasculitis in remission.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM) [Phase 4]
Phase 4 trial update exploring rituximab combined with telitacicept for ANCA-associated vasculitis, focusing on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis [Phase 3]
Phase 3 trial of avacopan (CCX168) in ANCA-associated vasculitis has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Rituximab and Belimumab Combination Therapy in PR3 Vasculitis [Phase 2]
A Phase 2 trial evaluating Rituximab and Belimumab combination therapy for ANCA-associated vasculitis, including granulomatosis with polyang…
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CLINICAL_TRIALS trial_result · 2020-07-27Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With ANCA-Associated Vasculitis [Phase 2]
Phase 2 study of avacopan (CCX168) in ANCA-associated vasculitis has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: The ANCA Vasculitis Questionnaire (AAV-PRO©)
The ANCA Vasculitis Questionnaire (AAV-PRO©) trial update notes that the study evaluating a patient-reported outcome instrument for ANCA-ass…
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Residual Anti-pneumococcal Immunity After Pneumococcal Immunization in ANCA-associated Vasculitis
This clinical trial update reports on residual anti-pneumococcal immunity following pneumococcal vaccination in patients with ANCA-associate…
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CLINICAL_TRIALS trial_result · 2016-05-20Clinical Trial Update: Defining Immune Tolerance in ANCA-associated Vasculitis (AAV)
The ANCA-associated vasculitis immune tolerance trial sponsored by NIAID was terminated, with results posted in 2016.