Anaplastic Oligoastrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA [Phase 2]
Phase 2 clinical trial investigating super selective intra-arterial cetuximab with reirradiation for relapsed or refractory glioblastoma, an…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas [Phase 2]
A Phase 2 clinical trial from MD Anderson is evaluating chemotherapy and radiation therapy for IDH-wildtype gliomas and non-histological (mo…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas
The clinical trial investigating microRNA-10b expression in glioma patients has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma [Phase 2]
Phase 2 trial comparing proton beam therapy with intensity-modulated radiation therapy for preserving brain function in IDH-mutant grade II/…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma [Phase 1]
Phase 1 study evaluating Ad-RTS-hIL-12 in combination with Veledimex for glioblastoma and malignant glioma has completed enrollment, with re…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS trial_result · 2024-01-03Clinical Trial Update: Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas [Phase 1]
Phase 1 trial evaluating adavosertib with local radiation in children with newly diagnosed diffuse intrinsic pontine glioma; results are pos…
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas [Phase 1, Phase 2]
Phase I/II trial of AXL1717 in recurrent malignant astrocytomas (glioblastoma, gliosarcoma) with terminated status and results posted.
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CLINICAL_TRIALS trial_result · 2023-01-20Clinical Trial Update: Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma [Phase 1]
Phase 1 trial update of neural stem cell–based virotherapy for newly diagnosed malignant glioma; study completed with results posted in 2023…
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CLINICAL_TRIALS trial_result · 2022-10-31Clinical Trial Update: A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme [Phase 3]
Phase III study investigating postoperative early temozolomide with the STUPP regimen for newly diagnosed glioblastoma multiforme; current s…
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CLINICAL_TRIALS trial_result · 2022-03-17Clinical Trial Update: Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors [Phase 1, Phase 2]
Phase 1/2 trial investigating a combination chemotherapy regimen (carboplatin, melphalan, etoposide phosphate, mannitol, and sodium thiosulf…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating Vorinostat with radiation followed by maintenance therapy in younger patients with newly diagnosed diffuse intrin…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor [Phase 1]
Phase 1 study evaluating Tocagen's retroviral replicating vector Toca 511 in combination with the prodrug 5-fluorocytosine for recurrent mal…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor [Phase 1]
This document reports the completion of a Phase 1 trial evaluating a retroviral replicating vector (Toca 511) given intravenously to patient…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma [Phase 1]
Phase 1 study evaluating the safety and feasibility of Toca 511, a retroviral replicating vector, in combination with the prodrug Toca FC in…
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas [Phase 3]
Phase 3 trial update on β-elemene as maintenance therapy for newly diagnosed malignant gliomas is ongoing, status currently unknown.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas [Phase 1]
Phase 1 feasibility trial evaluating oral 5-fluorocytosine in combination with genetically modified neural stem cells expressing E. coli cyt…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma [Phase 1]
Phase 1 clinical trial evaluating a vaccine therapy in combination with sargramostim (GM-CSF) for malignant glioma, including several glioma…
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CLINICAL_TRIALS research · 2016-06-10Clinical Trial Update: Study About the Validity of MRS-guided Resection on Prognosis High-grade Glioma Gliomas [NA]
An update on a clinical trial assessing whether magnetic resonance spectroscopy-guided resection improves prognosis for high-grade gliomas.
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery [Phase 1]
This clinical trial update reports on a Phase 1 study of the oncolytic herpes simplex virus HSV-1716 in children with refractory or recurren…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Temozolomide in Relapsed or Advanced Anaplastic Oligodendroglioma and Oligoastrocytoma: Single-arm, Phase II Trial [Phase 2]
A single-arm Phase II trial evaluated Temozolomide in relapsed or advanced anaplastic oligodendroglioma and anaplastic oligoastrocytoma. The…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas [Phase 2]
Results from a Phase II randomized trial in adults with recurrent high-grade gliomas comparing vandetanib with carboplatin followed by vande…
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CLINICAL_TRIALS withdrawal · 2015-05-12Clinical Trial Update: Re-irradiation of High Grade Gliomas: a Quality of Life Study
A clinical trial studying re-irradiation for high-grade gliomas with a quality-of-life focus has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Sorafenib in Newly Diagnosed High Grade Glioma [Phase 1]
Phase 1 trial update evaluating sorafenib in newly diagnosed high-grade glioma, including glioblastoma, gliosarcoma, and various anaplastic …
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CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: BIBF 1120 for Recurrent High-Grade Gliomas [Phase 2]
Phase 2 trial update on BIBF 1120 (nintedanib) for recurrent high-grade gliomas, with the study status now completed and results posted in 2…