Anaplastic Large Cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-24Clinical Trial Results: Brentuximab Vedotin and Bendamustine for the Treatment of Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma (ALCL) [Phase 1, Phase 2]
Phase 1/2 trial evaluating brentuximab vedotin in combination with bendamustine for Hodgkin lymphoma and anaplastic large cell lymphoma comp…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Safety Study of PF-08046044/SGN-35C in Adults With Advanced Cancers [Phase 1]
Phase 1 safety study update for PF-08046044/SGN-35C in adults with advanced cancers; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies. [Phase 1, Phase 2]
This document describes a Phase 1/Phase 2 clinical trial evaluating AZD3470 as a monotherapy or in combination with other anticancer agents …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma [Phase 1]
A Phase 1 clinical trial evaluating the VSV-hIFNβ-NIS vaccine with or without cyclophosphamide and in combination with ipilimumab, nivolumab…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers [Phase 2]
This Phase 2 clinical trial update evaluates the combination of talimogene laherparepvec (T-VEC) and nivolumab for patients with refractory …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma [Phase 1]
A Phase 1 clinical trial is evaluating intravenous vesicular stomatitis virus in patients with peripheral T-cell lymphoma and related condit…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL) [Phase 1]
Phase 1 study evaluating the combination of alectinib and duvelisib in ALK-positive anaplastic large cell lymphoma (ALK+ ALCL) is currently …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies [Phase 1]
Phase 1 trial evaluating an anti-CD30 bispecific antibody (AATC) in relapsed/refractory CD30-positive hematologic malignancies; currently re…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Nivolumab for Pediatric and Adult Relapsing/Refractory ALK+, for Evaluation of Response in Patients With Progressive Disease (Cohort 1) or as Consolidative Immunotherapy in Patients in Complete Remission After Relapse (Cohort 2) [Phase 2]
A Phase 2 trial evaluating nivolumab in pediatric and adult patients with relapsed/refractory ALK-positive anaplastic large cell lymphoma, a…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma [Phase 1]
Phase 1 trial evaluating azacitidine with abatacept for relapsed or refractory T-cell lymphomas is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: BV-CHP Real-life and Biological Evidences in Patients With sALCL
This trial update from Fondazione Italiana Linfomi- ETS describes real-life and biological evidence regarding the BV-CHP regimen (brentuxima…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Crizotinib Continuation Clinical Study [Phase 4]
A Phase 4 continuation study of crizotinib sponsored by Pfizer is currently active but not recruiting. The study investigates crizotinib in …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: CCCG-ALCL-2020 for Chinese Children and Adolescents With Newly Diagnosed High-risk ALCL [Phase 3]
A Phase 3 clinical trial (CCCG-ALCL-2020) in Chinese children and adolescents with newly diagnosed high-risk anaplastic large cell lymphoma …
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma [Phase 1, Phase 2]
Clinical trial update for AUTO4 in TRBC1-positive T-cell lymphomas shows Phase 1/2 results with the study terminated and results posted.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) [Phase 1]
A Phase 1 clinical trial is evaluating CCR4-directed CAR T cells in CCR4-expressing mature T-cell malignancies, including peripheral T-cell …
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: A Safety Study of PF-08046045/SGN-35T in Adults With Advanced Cancers [Phase 1]
A Phase 1 safety study of PF-08046045/SGN-35T sponsored by Seagen has been terminated in adults with advanced lymphomas and Hodgkin disease.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Combination With Romidepsin [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pembrolizumab in combination with romidepsin for recurrent or refractory T-cell lymphomas; the study i…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency [NA]
A Mayo Clinic-sponsored clinical trial evaluates cholecalciferol (vitamin D3) for improving survival in patients with newly diagnosed cancer…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors [Phase 1, Phase 2]
A phase 1/2 clinical trial update indicates brigatinib is currently recruiting pediatric and young adult patients with ALK-positive Anaplast…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers [Phase 2, Phase 3]
The DETERMINE trial treatment arm 01 is evaluating Alectinib in adult, paediatric and teenage/young adult patients with ALK-positive cancers…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Chemoimmunotherapy for ALK+ Relapsed/Refractory ALCL [Phase 2]
Phase 2 trial update for chemoimmunotherapy in relapsed/refractory ALK-positive anaplastic large cell lymphoma; the study is currently activ…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial from MD Anderson evaluating AFM13 and AFM13-NK in patients with recurrent or refractory CD30-po…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Previously Untreated Aggressive Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial evaluating dose-adjusted EPOCH chemotherapy plus Rituximab in previously untreated aggressive non-Hodgkin lymphoma has complet…
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CLINICAL_TRIALS withdrawal · 2025-06-12Clinical Trial Update: Triamcinolone Acetonide Injections in Primary Cutaneous Lymphoma Plaques With a Novel Needle-free Drug-delivery System. [NA]
A clinical trial evaluating Triamcinolone acetonide injections with a novel needle-free delivery system for primary cutaneous lymphoma plaqu…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies [Phase 1]
Phase 1 trial evaluating anti-CD7 CAR-T cell therapy for relapsed/refractory CD7-positive T-cell malignancies has completed, assessing safet…