Anaplastic Ependymoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (lutetium-177 dotatate) for recurrent or progressive high-grade central nervous system tumor…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1]
A Phase 1 pediatric trial of SurVaxM for progressive or relapsed medulloblastoma, high-grade glioma, ependymoma, and newly diagnosed diffuse…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: LET Optimized IMPT in Treating Pediatric Patients With Ependymoma [Phase 1]
A Phase 1 clinical trial from MD Anderson is evaluating LET-optimized intensity-modulated proton therapy (IMPT) for pediatric ependymoma and…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine [Phase 1]
A Phase 1 trial of the Heat Shock Protein Peptide Complex-96 (HSPPC-96) vaccine for glioblastoma and related CNS tumors was terminated. The …
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
A Phase 1 trial evaluating Lapatinib Ditosylate before surgical resection in adults with recurrent high-grade glioma has completed. The stud…
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CLINICAL_TRIALS withdrawal · 2024-10-26Clinical Trial Update: Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer [Phase 1]
A Phase 1 trial investigating chemotherapy and donor stem cell transplantation for high-grade brain cancers has been withdrawn. The study in…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors [Phase 1]
The SJDAWN Phase 1 trial at St. Jude evaluated molecularly-driven doublet therapies for children and young adults with recurrent brain tumor…
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas [Phase 1, Phase 2]
Phase I/II trial of AXL1717 in recurrent malignant astrocytomas (glioblastoma, gliosarcoma) with terminated status and results posted.
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CLINICAL_TRIALS trial_result · 2021-12-28Clinical Trial Update: Carboplatin and Bevacizumab for Recurrent Ependymoma [Phase 2]
Phase 2 trial of carboplatin plus bevacizumab for recurrent ependymoma has completed, and results have been posted. The study evaluated effi…
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma [Phase 2]
Phase 2 trial of marizomib for recurrent ependymoma in various locations was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-03-12Clinical Trial Update: Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas [Phase 2]
Phase 2 trial evaluating hypofractionated external radiotherapy with bevacizumab and temozolomide for recurrent gliomas; the study was termi…
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CLINICAL_TRIALS trial_result · 2019-09-09Clinical Trial Update: Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas [Phase 1]
Phase 1 trial evaluating alisertib in combination with fractionated stereotactic radiosurgery for adults with recurrent high-grade gliomas h…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors [Phase 2]
A Phase 2 trial evaluating imetelstat in younger patients with recurrent or refractory brain tumors was terminated, with results posted in J…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases [Phase 1]
This Phase 1 trial assessing bafetinib in adults with recurrent high-grade glioma or brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: 3T MRI Biomarkers of Glioma Treatment Response [EARLY_Phase 1]
An early-phase 1 trial evaluating 3T MRI biomarkers for glioma treatment response, sponsored by Vanderbilt-Ingram Cancer Center, has been te…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 [Phase 1]
Phase I trial evaluating intratumoral GRm13Z40-2 T-cell therapy (genetically modified allogeneic CD8+ T cells expressing IL-13-Zetakine and …
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated the combination of RO4929097, a gamma-secretase inhibitor, with Cediranib maleate in adults with advanced solid…
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CLINICAL_TRIALS trial_result · 2013-06-14Clinical Trial Update: Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating bevacizumab to reduce central nervous system side effects after brain radiotherapy in patients with various brain t…
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CLINICAL_TRIALS trial_result · 2013-06-10Clinical Trial Update: Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma [Phase 2]
A Phase 2 clinical trial evaluating ritonavir and lopinavir for progressive or recurrent high-grade glioma was terminated, with results post…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction [Phase 1]
Phase 1 clinical trial evaluating erlotinib in patients with solid tumors and liver or kidney dysfunction has been completed.
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CLINICAL_TRIALS withdrawal · 2010-01-12Clinical Trial Update: Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors [Phase 2]
Phase 2 trial of photodynamic therapy for malignant intracranial tumors has been withdrawn from ClinicalTrials.gov.